期刊
ACS CHEMICAL NEUROSCIENCE
卷 11, 期 15, 页码 2137-2144出版社
AMER CHEMICAL SOC
DOI: 10.1021/acschemneuro.0c00335
关键词
SARS-CoV-2; COVID19; CNS infection; drug treatment; log P; CNS penetration
Now, it has been evidenced that Covid19 (SARS-CoV-2) infects the brain tissues. Along with this, a challenge has been raised for research professionals to find effective drugs for its treatment since the recent spread of this virus from Wuhan, China. Targeting the treatment of brain infection, it has also been a challenge that the clinical drug should have good CNS penetration ability to cross the blood-brain barrier.
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