相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Organoids for Drug Discovery and Personalized Medicine
Toshio Takahashi
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 59 (2019)
Establishing Cerebral Organoids as Models of Human-Specific Brain Evolution
Alex A. Pollen et al.
CELL (2019)
OLIG2 Drives Abnormal Neurodevelopmental Phenotypes in Human iPSC-Based Organoid and Chimeric Mouse Models of Down Syndrome
Ranjie Xu et al.
CELL STEM CELL (2019)
Specification of positional identity in forebrain organoids
Gustav Y. Cederquist et al.
NATURE BIOTECHNOLOGY (2019)
Individual brain organoids reproducibly form cell diversity of the human cerebral cortex
Silvia Velasco et al.
NATURE (2019)
Modeling microcephaly with cerebral organoids reveals a WDR62-CEP170-KIF2A pathway promoting cilium disassembly in neural progenitors
Wei Zhang et al.
NATURE COMMUNICATIONS (2019)
Gain of 20q11.21 in Human Pluripotent Stem Cells Impairs TGF-β-Dependent Neuroectodermal Commitment
C. Markouli et al.
STEM CELL REPORTS (2019)
Organoid single-cell genomic atlas uncovers human-specific features of brain development
Sabina Kanton et al.
NATURE (2019)
Organoids required! A new path to understanding human brain development and disease
Paola Arlotta
NATURE METHODS (2018)
Generation of human brain region-specific organoids using a miniaturized spinning bioreactor
Xuyu Qian et al.
NATURE PROTOCOLS (2018)
Six-month cultured cerebral organoids from human ES cells contain matured neural cells
Takeshi K. Matsui et al.
NEUROSCIENCE LETTERS (2018)
Progress and potential in organoid research
Giuliana Rossi et al.
NATURE REVIEWS GENETICS (2018)
Brain Organoids and the Study of Neurodevelopment
Cleber A. Trujillo et al.
TRENDS IN MOLECULAR MEDICINE (2018)
Dlk1-Dio3 locus-derived lncRNAs perpetuate postmitotic motor neuron cell fate and subtype identity
Ya-Ping Yen et al.
ELIFE (2018)
CYP3A5 Mediates Effects of Cocaine on Human Neocorticogenesis: Studies using an In Vitro 3D Self-Organized hPSC Model with a Single Cortex-Like Unit
Chun-Ting Lee et al.
NEUROPSYCHOPHARMACOLOGY (2017)
Cell diversity and network dynamics in photosensitive human brain organoids
Giorgia Quadrato et al.
NATURE (2017)
Self-patterning of rostral-caudal neuroectoderm requires dual role of Fgf signaling for localized Wnt antagonism
Nozomu Takata et al.
NATURE COMMUNICATIONS (2017)
Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection
Momoko Watanabe et al.
CELL REPORTS (2017)
Short term changes in the proteome of human cerebral organoids induced by 5-MeO-DMT
Vanja Dakic et al.
SCIENTIFIC REPORTS (2017)
Present and future of modeling human brain development in 3D organoids
Giorgia Quadrato et al.
CURRENT OPINION IN CELL BIOLOGY (2017)
Self-organized developmental patterning and differentiation in cerebral organoids
Magdalena Renner et al.
EMBO JOURNAL (2017)
Human iPSC-Derived Cerebral Organoids Model Cellular Features of Lissencephaly and Reveal Prolonged Mitosis of Outer Radial Glia
Marina Bershteyn et al.
CELL STEM CELL (2017)
The hope and the hype of organoid research
Meritxell Huch et al.
DEVELOPMENT (2017)
Induction of Expansion and Folding in Human Cerebral Organoids
Yun Li et al.
CELL STEM CELL (2017)
The mitochondrial protein CHCHD2 primes the differentiation potential of human induced pluripotent stem cells to neuroectodermal lineages
Lili Zhu et al.
JOURNAL OF CELL BIOLOGY (2016)
Enhanced Generation of Integration-free iPSCs from Human Adult Peripheral Blood Mononuclear Cells with an Optimal Combination of Episomal Vectors
Wei Wen et al.
STEM CELL REPORTS (2016)
Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture
Anca M. Pasca et al.
NATURE METHODS (2015)
Human cerebral organoids recapitulate gene expression programs of fetal neocortex development
J. Gray Camp et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Self-Organization of Polarized Cerebellar Tissue in 3D Culture of Human Pluripotent Stem Cells
Keiko Muguruma et al.
CELL REPORTS (2015)
CHCHD2 inhibits apoptosis by interacting with Bcl-x L to regulate Bax activation
Y. Liu et al.
CELL DEATH AND DIFFERENTIATION (2015)
A comparison of non-integrating reprogramming methods
Thorsten M. Schlaeger et al.
NATURE BIOTECHNOLOGY (2015)
Cerebral organoids model human brain development and microcephaly
Nobutaka Hattori
MOVEMENT DISORDERS (2014)
Tgfβ Signaling Regulates Temporal Neurogenesis and Potency of Neural Stem Cells in the CNS
Jose M. Dias et al.
NEURON (2014)
Comparative study of human-induced pluripotent stem cells derived from bone marrow cells, hair keratinocytes, and skin fibroblasts
Katrin Streckfuss-Boemeke et al.
EUROPEAN HEART JOURNAL (2013)
Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell-derived neocortex
Taisuke Kadoshima et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Histone Acetyl Transferase 1 Is Essential for Mammalian Development, Genome Stability, and the Processing of Newly Synthesized Histones H3 and H4
Prabakaran Nagarajan et al.
PLOS GENETICS (2013)
The dynamic role of bone morphogenetic proteins in neural stem cell fate and maturation
Allison M. Bond et al.
DEVELOPMENTAL NEUROBIOLOGY (2012)
Application of Rho-associated protein kinase (ROCK) inhibitor to human pluripotent stem cells
Hiroshi Kurosawa
JOURNAL OF BIOSCIENCE AND BIOENGINEERING (2012)
Generation of human induced pluripotent stem cells from urine samples
Ting Zhou et al.
NATURE PROTOCOLS (2012)
A Genome-Wide RNAi Screen Reveals MAP Kinase Phosphatases as Key ERK Pathway Regulators during Embryonic Stem Cell Differentiation
Shen-Hsi Yang et al.
PLOS GENETICS (2012)
Specific lectin biomarkers for isolation of human pluripotent stem cells identified through array-based glycomic analysis
Yu-Chieh Wang et al.
CELL RESEARCH (2011)
Wnt Signaling Regulates Neuronal Differentiation of Cortical Intermediate Progenitors
Roeben N. Munji et al.
JOURNAL OF NEUROSCIENCE (2011)
A bioinformatic assay for pluripotency in human cells
Franz-Josef Mueller et al.
NATURE METHODS (2011)
Targeting endoplasmic reticulum stress and Akt with OSU-03012 and gefitinib or erlotinib to overcome resistance to epidermal growth factor receptor inhibitors
Yu-Chieh Wang et al.
CANCER RESEARCH (2008)
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
Kazutoshi Takahashi et al.
CELL (2007)
Molecular mechanisms controlling cortical gliogenesis
CM Sauvageot et al.
CURRENT OPINION IN NEUROBIOLOGY (2002)
分享论文
