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Qian Liu et al.
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S. Baldacci et al.
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Federica Papaccio et al.
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Sai-Hong Ignatius et al.
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FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2017)
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Giorgio Scagliotti et al.
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[Anonymous]
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MOLECULAR ONCOLOGY (2014)
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CELL DEATH & DISEASE (2014)
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BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
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BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2013)
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CURRENT OPINION IN PHARMACOLOGY (2013)
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SCIENCE TRANSLATIONAL MEDICINE (2012)
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MOLECULAR CANCER RESEARCH (2010)
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BLOOD (2008)
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EUROPEAN JOURNAL OF CANCER (2008)
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K Okunishi et al.
JOURNAL OF IMMUNOLOGY (2005)
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KA Furge et al.
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