New Hybrid Bioactive Composites for Bone Substitution

Recently, intensive efforts have been undertaken to find new, superior biomaterial solutions in the field of hybrid inorganic-organic materials. In our studies, biomicroconcretes containing hydroxyapatite (HAp)-chitosan (CTS) granules dispersed in an ff tricalcium phospahate (ffTCP) matrix were investigated. The influence of CTS content and the size of granules on the physicochemical properties of final bone implant materials (setting time, porosity, mechanical strength, and phase composition) were evaluated. The obtained materials were found to be promising bone substitutes for use in non-load bearing applications.