期刊
ENVIRONMENTAL SCIENCES EUROPE
卷 32, 期 1, 页码 -出版社
SPRINGER
DOI: 10.1186/s12302-020-00357-y
关键词
Antibiotic resistance genes; Drinking water reservoir; Antibiotic residues
资金
- National Natural Science Foundation of China [21906121, 21876135, 21876136]
- Foundation of Key Laboratory of Yangtze River Water Environment (Tongji University), Ministry of Education, China [YRWEF201803]
- International Science and Technology Cooperation Program of China [2016YFE0123700]
Background Aquatic ecosystems are considered to be among the most important reservoirs of antibiotic resistance genes (ARGs). Drinking water sources could serve as critical points of ARGs transfer from environment to human. In this study, the distribution of antibiotics and ARGs across Qingcaosha Reservoir located in the Yangtze River Delta during three seasons was investigated to characterize the pollution patterns. Results Sulfamethoxazole, sulfamonomethoxine and penicillin G potassium salt were the dominant antibiotics in this reservoir. Sulfonamide resistance genes (sul1 and sul2) were the most prevalent and predominant genes. Higher total relative abundance of the ARGs was detected in the site closest to the inflow than those in other sites. Overall, the concentrations of antibiotics in May were relatively lower than those in November and February. Correlation analysis indicated sul1, ermB and mphA had positive correlation with corresponding antibiotics in February and sul1, sul2, ermB and mphA was also positively correlated to intI1. Conclusion In conclusion, antibiotics and ARGs were widespread in Qingcaosha Reservoir. Our results indicated that the drinking water reservoir might serve as gene reservoir for antibiotic resistance and mobile gene element intI1 can serve as a medium to contribute to the widespread of various ARGs. As the ARGs abundance was found to be higher in the inflow of the reservoir compared to the outflow, it is considered that reservoir could serve as a functional area contributing to the elimination or dilution of ARGs.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据