相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Tumor Microenvironment: A Metabolic Player that Shapes the Immune Response
Shamir Cassim et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Lactate: A Metabolic Driver in the Tumour Landscape
Luigi Ippolito et al.
TRENDS IN BIOCHEMICAL SCIENCES (2019)
Clinical significance of metabolism-related biomarkers in non-Hodgkin lymphoma-MCT1 as potential target in diffuse large B cell lymphoma
Julieta Afonso et al.
CELLULAR ONCOLOGY (2019)
Expression of Monocarboxylate Transporter 1 Is Associated With Better Prognosis and Reduced Nodal Metastasis in Pancreatic Ductal Adenocarcinoma
Aoi Sukeda et al.
PANCREAS (2019)
Metabolic regulation of gene expression by histone lactylation
Di Zhang et al.
NATURE (2019)
Lactate in the Regulation of Tumor Microenvironment and Therapeutic Approaches
Karen G. de la Cruz-Lopez et al.
FRONTIERS IN ONCOLOGY (2019)
Cancer-associated fibroblasts modify lung cancer metabolism involving ROS and TGF-β signaling
Alberto Cruz-Bermudez et al.
FREE RADICAL BIOLOGY AND MEDICINE (2019)
MCT4 has a potential to be used as a prognostic biomarker - a systematic review and meta-analysis
Arslaan Javaeed et al.
ONCOLOGY REVIEWS (2019)
The prognostic significance of the expression of monocarboxylate transporter 4 in patients with right- or left-sided colorectal cancer
Yukio Abe et al.
ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY (2019)
Stromal-epithelial lactate shuttle induced by tumor-derived interleukin-1β promotes cell proliferation in oral squamous cell carcinoma
Jie Wu et al.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2018)
Colorectal cancer cell-derived exosomes containing miR-10b regulate fibroblast cells via the PI3K/Akt pathway
Guangyao Dai et al.
BULLETIN DU CANCER (2018)
Cancer-Associated Fibroblasts Drive Glycolysis in a Targetable Signaling Loop Implicated in Head and Neck Squamous Cell Carcinoma Progression
Dhruv Kumar et al.
CANCER RESEARCH (2018)
Including the mitochondrial metabolism of L-lactate in cancer metabolic reprogramming
Lidia de Bari et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2018)
Meta-analysis of serum lactate dehydrogenase and prognosis for osteosarcoma
Yucheng Fu et al.
MEDICINE (2018)
The two glycolytic markers GLUT1 and MCT1 correlate with tumor grade and survival in clear-cell renal cell carcinoma
Damien Ambrosetti et al.
PLOS ONE (2018)
Monocarboxylate transporters MCT1 and MCT4 are independent prognostic biomarkers for the survival of patients with clear cell renal cell carcinoma and those receiving therapy targeting angiogenesis
Yan-Wei Cao et al.
UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS (2018)
Phosphoinositide 3-Kinase/Akt Signaling and Redox Metabolism in Cancer
Nikos Koundouros et al.
FRONTIERS IN ONCOLOGY (2018)
Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies
Maria Apicella et al.
CELL METABOLISM (2018)
Tumor immunoevasion via acidosis-dependent induction of regulatory tumor-associated macrophages
Toszka Bohn et al.
NATURE IMMUNOLOGY (2018)
Lactate dehydrogenase A: A key player in carcinogenesis and potential target in cancer therapy
Yangbo Feng et al.
CANCER MEDICINE (2018)
Higher pretreatment lactate dehydrogenase concentration predicts worse overall survival in patients with lung cancer
Taibing Deng et al.
MEDICINE (2018)
Reexamining cancer metabolism: lactate production for carcinogenesis could be the purpose and explanation of the Warburg Effect
Inigo San-Millan et al.
CARCINOGENESIS (2017)
Lactate at the crossroads of metabolism, inflammation, and autoimmunity
Valentina Pucino et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2017)
Metabolic Pathways of the Warburg Effect in Health and Disease: Perspectives of Choice, Chain or Chance
Jorge S. Burns et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Metabolic cooperation between co-cultured lung cancer cells and lung fibroblasts
Michael I. Koukourakis et al.
LABORATORY INVESTIGATION (2017)
Monocarboxylate transporter 1 is a key player in glioma-endothelial cell crosstalk
Vera Miranda-Goncalves et al.
MOLECULAR CARCINOGENESIS (2017)
Tumor cell-derived lactate induces TAZ-dependent upregulation of PD-L1 through GPR81 in human lung cancer cells
J. Feng et al.
ONCOGENE (2017)
Cancer-associated fibroblasts enhance pancreatic cancer cell invasion by remodeling the metabolic conversion mechanism
Tao Shan et al.
ONCOLOGY REPORTS (2017)
Lactic Acid: No Longer an Inert and End-Product of Glycolysis
Shiren Sun et al.
PHYSIOLOGY (2017)
Gpr132 sensing of lactate mediates tumor-macrophage interplay to promote breast cancer metastasis
Peiwen Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Value of pH regulators in the diagnosis, prognosis and treatment of cancer
Sara Granja et al.
SEMINARS IN CANCER BIOLOGY (2017)
Mitochondrial and glycolytic metabolic compartmentalization in diffuse large B-cell lymphoma
Mahasweta Gooptu et al.
SEMINARS IN ONCOLOGY (2017)
Lactate-activated macrophages induced aerobic glycolysis and epithelial-mesenchymal transition in breast cancer by regulation of CCL5-CCR5 axis: a positive metabolic feedback loop
Sensen Lin et al.
ONCOTARGET (2017)
Radiosynthesis and validation of (±)-[18F]-3-fluoro-2-hydroxypropionate ([18F]-FLac) as a PET tracer of lactate to monitor MCT1-dependent lactate uptake in tumors
Vincent F. Van Hee et al.
ONCOTARGET (2017)
The Glycolytic Switch in Tumors: How Many Players Are Involved?
Li Yu et al.
JOURNAL OF CANCER (2017)
Lactate Shuttles in Neuroenergetics - Homeostasis, Allostasis and Beyond
Shayne Mason
FRONTIERS IN NEUROSCIENCE (2017)
Strategies to improve the efficacy of Dendritic Cell-Based immunotherapy for Melanoma
Kristian M. Hargadon
FRONTIERS IN IMMUNOLOGY (2017)
Metabolic Hallmarks of Tumor and immune Cells in the Tumor Microenvironment
Kathrin Renner et al.
FRONTIERS IN IMMUNOLOGY (2017)
Metabolic zonation of the liver: The oxygen gradient revisited
Thomas Kietzmann
REDOX BIOLOGY (2017)
Tumor LDH-A expression and serum LDH status are two metabolic predictors for triple negative breast cancer brain metastasis
Tieying Dong et al.
SCIENTIFIC REPORTS (2017)
GLUT1, MCT1/4 and CD147 overexpression supports the metabolic reprogramming in papillary renal cell carcinoma
L. M. C. A. Almeida et al.
HISTOLOGY AND HISTOPATHOLOGY (2017)
Cell-surface G-protein-coupled receptors for tumor-associated metabolites: A direct link to mitochondrial dysfunction in cancer
Bojana Ristic et al.
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER (2017)
A first-in-human first-in-class (FIC) trial of the monocarboxylate transporter 1 (MCT1) inhibitor AZD3965 in patients with advanced solid tumours.
Sarah E. R. Halford et al.
JOURNAL OF CLINICAL ONCOLOGY (2017)
Metabolic coupling in urothelial bladder cancer compartments and its correlation to tumor aggressiveness
Julieta Afonso et al.
CELL CYCLE (2016)
Lactate promotes glutamine uptake and metabolism in oxidative cancer cells
Jhudit Perez-Escuredo et al.
CELL CYCLE (2016)
Basigin (CD147), a multifunctional transmembrane glycoprotein with various binding partners
Takashi Muramatsu
JOURNAL OF BIOCHEMISTRY (2016)
Prognostic significance of monocarboxylate transporter expression in oral cavity tumors
Susana Simoes-Sousa et al.
CELL CYCLE (2016)
The metabolic microenvironment of melanomas: Prognostic value of MCT1 and MCT4
Celine Pinheiro et al.
CELL CYCLE (2016)
In Vivo Evidence for a Lactate Gradient from Astrocytes to Neurons
Philipp Machler et al.
CELL METABOLISM (2016)
Proteomics Unveils Fibroblast-Cardiomyocyte Lactate Shuttle and Hexokinase Paradox in Mouse Muscles
Dariusz Rakus et al.
JOURNAL OF PROTEOME RESEARCH (2016)
Proteomic identification of the lactate dehydrogenase A in a radioresistant prostate cancer xenograft mouse model for improving radiotherapy
Jingli Hao et al.
ONCOTARGET (2016)
G-protein-coupled receptor 81 promotes a malignant phenotype in breast cancer through angiogenic factor secretion
Yu Jin Lee et al.
ONCOTARGET (2016)
Metabolic Symbiosis Enables Adaptive Resistance to Anti-angiogenic Therapy that Is Dependent on mTOR Signaling
Elizabeth Allen et al.
CELL REPORTS (2016)
Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism
Hongyun Zhao et al.
ELIFE (2016)
Prognostic Role of Lactate Dehydrogenase Expression in Urologic Cancers: A Systematic Review and Meta-Analysis
Yong Zhang et al.
ONCOLOGY RESEARCH AND TREATMENT (2016)
Lactate Contribution to the Tumor Microenvironment: Mechanisms, effects on immune Cells and Therapeutic Relevance
Susana Romero-Garcia et al.
FRONTIERS IN IMMUNOLOGY (2016)
Prognostic role of lactate dehydrogenase in solid tumors: A systematic review and meta-analysis of 76 studies
Fausto Petrelli et al.
ACTA ONCOLOGICA (2015)
A Lactate-Induced Response to Hypoxia
Dong Chul Lee et al.
CELL (2015)
L- and D-lactate enhance DNA repair and modulate the resistance of cervical carcinoma cells to anticancer drugs via histone deacetylase inhibition and hydroxycarboxylic acid receptor 1 activation
Waldemar Wagner et al.
CELL COMMUNICATION AND SIGNALING (2015)
Expression of lactate/H+ symporters MCT1 and MCT4 and their chaperone CD147 predicts tumor progression in clear cell renal cell carcinoma: immunohistochemicat and The Cancer Genome Atlas data analyses
Younghye Kim et al.
HUMAN PATHOLOGY (2015)
Warburg-like Glycolysis and Lactate Shuttle in Mouse Decidua during Early Pregnancy
Ru-Juan Zuo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Hyperpolarized 13C NMR observation of lactate kinetics in skeletal muscle
Jae Mo Park et al.
JOURNAL OF EXPERIMENTAL BIOLOGY (2015)
Metabolic reprogramming: a new relevant pathway in adult adrenocortical tumors
Celine Pinheiro et al.
ONCOTARGET (2015)
Targeting stromal-induced pyruvate kinase M2 nuclear translocation impairs OXPHOS and prostate cancer metastatic spread
Elisa Giannoni et al.
ONCOTARGET (2015)
Bladder cancer cells re-educate TAMs through lactate shuttling in the microfluidic cancer microenvironment
Yang Zhao et al.
ONCOTARGET (2015)
Lactate Regulates Metabolic and Proinflammatory Circuits in Control of T Cell Migration and Effector Functions
Robert Haas et al.
PLOS BIOLOGY (2015)
Prognostic Indications of Elevated MCT4 and CD147 across Cancer Types: A Meta-Analysis
Cory D. Bovenzi et al.
BIOMED RESEARCH INTERNATIONAL (2015)
Glucose metabolism regulatesT cell activation, differentiation, and functions
Clovis S. Palmer et al.
FRONTIERS IN IMMUNOLOGY (2015)
Monocarboxylate transporter 4 predicts poor prognosis in hepatocellular carcinoma and is associated with cell proliferation and migration
Heng-Jun Gao et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2015)
CD147 and MCT1-potential partners in bladder cancer aggressiveness and cisplatin resistance
Julieta Afonso et al.
MOLECULAR CARCINOGENESIS (2015)
A Pilot Proteogenomic Study with Data Integration Identifies MCT1 and GLUT1 as Prognostic Markers in Lung Adenocarcinoma
Paul A. Stewart et al.
PLOS ONE (2015)
Disruption of BASIGIN decreases lactic acid export and sensitizes non-small cell lung cancer to biguanides independently of the LKB1 status
Sara Granja et al.
ONCOTARGET (2015)
T-cell metabolism in autoimmune disease
Zhen Yang et al.
ARTHRITIS RESEARCH & THERAPY (2015)
Expression of the hypoxia-inducible monocarboxylate transporter MCT4 is increased in triple negative breast cancer and correlates independently with clinical outcome
J. Doyen et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
A lactate shuttle system between tumour and stromal cells is associated with poor prognosis in prostate cancer
Nelma Pertega-Gomes et al.
BMC CANCER (2014)
Cell Surface Lactate Receptor GPR81 Is Crucial for Cancer Cell Survival
Christina L. Roland et al.
CANCER RESEARCH (2014)
FOXM1 Promotes the Warburg Effect and Pancreatic Cancer Progression via Transactivation of LDHA Expression
Jiujie Cui et al.
CLINICAL CANCER RESEARCH (2014)
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
Oscar R. Colegio et al.
NATURE (2014)
β2-ADRENERGIC RECEPTORS PROTECT AXONS DURING ENERGETIC STRESS BUT DO NOT INFLUENCE BASAL GLIO-AXONAL LACTATE SHUTTLING IN MOUSE WHITE MATTER
G. Laureys et al.
NEUROSCIENCE (2014)
Synergistic Anti-Cancer Effect of Phenformin and Oxamate
W. Keith Miskimins et al.
PLOS ONE (2014)
Monocarboxylate Transporters 1-4 in NSCLC: MCT1 Is an Independent Prognostic Marker for Survival
Marte Eilertsen et al.
PLOS ONE (2014)
Prognostic Significance of Lactate/Proton Symporters MCT1, MCT4, and Their Chaperone CD147 Expressions in Urothelial Carcinoma of the Bladder
Jung-Woo Choi et al.
UROLOGY (2014)
Characterization of monocarboxylate transporter activity in hepatocellular carcinoma
Venancio A. Alves et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2014)
Acidity Generated by the Tumor Microenvironment Drives Local Invasion
Veronica Estrella et al.
CANCER RESEARCH (2013)
Cancer metabolism, stemness and tumor recurrence: MCT1 and MCT4 are functional biomarkers of metabolic symbiosis in head and neck cancer
Joseph M. Curry et al.
CELL CYCLE (2013)
The SLC16 gene family - Structure, role and regulation in health and disease
Andrew P. Halestrap
MOLECULAR ASPECTS OF MEDICINE (2013)
Etiology and Therapeutic Approach to Elevated Lactate Levels
Lars W. Andersen et al.
MAYO CLINIC PROCEEDINGS (2013)
Monocarboxylate transporters (MCTs) in gliomas: expression and exploitation as therapeutic targets
Vera Miranda-Goncalves et al.
NEURO-ONCOLOGY (2013)
Reverse Warburg Effect in a Patient With Aggressive B-Cell Lymphoma: Is Lactic Acidosis a Paraneoplastic Syndrome?
Ubaldo E. Martinez-Outschoorn et al.
SEMINARS IN ONCOLOGY (2013)
LDHA is necessary for the tumorigenicity of esophageal squamous cell carcinoma
Feng Yao et al.
TUMOR BIOLOGY (2013)
Lactate dehydrogenase A is overexpressed in pancreatic cancer and promotes the growth of pancreatic cancer cells
Yefei Rong et al.
TUMOR BIOLOGY (2013)
Tumor lactic acidosis suppresses CTL function by inhibition of p38 and JNK/c-Jun activation
Anna N. Mendler et al.
INTERNATIONAL JOURNAL OF CANCER (2012)
Brain lactate metabolism: the discoveries and the controversies
Gerald A. Dienel
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2012)
Importance of glycolysis and oxidative phosphorylation in advanced melanoma
Jonhan Ho et al.
MOLECULAR CANCER (2012)
Synthesis of cytochrome c oxidase 2: a p53-dependent metabolic regulator that promotes respiratory function and protects glioma and colon cancer cells from hypoxia-induced cell death
C. Wanka et al.
ONCOGENE (2012)
Targeting the Lactate Transporter MCT1 in Endothelial Cells Inhibits Lactate-Induced HIF-1 Activation and Tumor Angiogenesis
Pierre Sonveaux et al.
PLOS ONE (2012)
Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation
Sophia Y. Lunt et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 27 (2011)
Monocarboxylate transporter 4 (MCT4) and CD147 overexpression is associated with poor prognosis in prostate cancer
Nelma Pertega-Gomes et al.
BMC CANCER (2011)
Lactate Influx through the Endothelial Cell Monocarboxylate Transporter MCT1 Supports an NF-κB/IL-8 Pathway that Drives Tumor Angiogenesis
Frederique Vegran et al.
CANCER RESEARCH (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Cellular expression of monocarboxylate transporters in the female reproductive organ of mice: implications for the genital lactate shuttle
Takuya Kuchiiwa et al.
HISTOCHEMISTRY AND CELL BIOLOGY (2011)
Lactate enhances motility of tumor cells and inhibits monocyte migration and cytokine release
Kristina Goetze et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2011)
Adipose Tissue Lipolysis Revisited (Again!): Lactate Involvement in Insulin Antilipolytic Action
Dominique Langin
CELL METABOLISM (2010)
Co-expression of CD147/EMMPRIN with monocarboxylate transporters and multiple drug resistance proteins is associated with epithelial ovarian cancer progression
Hongmin Chen et al.
CLINICAL & EXPERIMENTAL METASTASIS (2010)
HIF-1: upstream and downstream of cancer metabolism
Gregg L. Semenza
CURRENT OPINION IN GENETICS & DEVELOPMENT (2010)
Lactate-Dehydrogenase 5 is overexpressed in non-small cell lung cancer and correlates with the expression of the transketolase-like protein 1
Gian Kayser et al.
DIAGNOSTIC PATHOLOGY (2010)
Monocarboxylate transporter 1 is up-regulated in basal-like breast carcinoma
Celine Pinheiro et al.
HISTOPATHOLOGY (2010)
The reverse Warburg effect Aerobic glycolysis in cancer associated fibroblasts and the tumor stroma
Stephanos Pavlides et al.
CELL CYCLE (2009)
Monocarboxylate transporters 1 and 4 are associated with CD147 in cervical carcinoma
Celine Pinheiro et al.
DISEASE MARKERS (2009)
The prognostic value of CD147/EMMPRIN is associated with monocarboxylate transporter 1 co-expression in gastric cancer
Celine Pinheiro et al.
EUROPEAN JOURNAL OF CANCER (2009)
CD147 silencing inhibits lactate transport and reduces malignant potential of pancreatic cancer cells in in vivo and in vitro models
W. Schneiderhan et al.
GUT (2009)
Lactate Inhibits Lipolysis in Fat Cells through Activation of an Orphan G-protein-coupled Receptor, GPR81
Changlu Liu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Metabolic Enzymes as Oncogenes or Tumor Suppressors
Craig B. Thompson
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
Matthew G. Vander Heiden et al.
SCIENCE (2009)
Overview of the proton-coupled MCT (SLC16A) family of transporters:: Characterization, function and role in the transport of the drug of abuse γ-hydroxybutyric acid
Marilyn E. Morris et al.
AAPS JOURNAL (2008)
Tumor cell metabolism: Cancer's Achilles' heel
Guido Kroemer et al.
CANCER CELL (2008)
Increasing expression of monocarboxylate transporters 1 and 4 along progression to invasive cervical carcinoma
Celine Pinheiro et al.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY (2008)
Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice
Pierre Sonveaux et al.
JOURNAL OF CLINICAL INVESTIGATION (2008)
Tumor-secreted lactic acid promotes IL-23/IL-17 proinflammatory pathway
Hiroaki Shime et al.
JOURNAL OF IMMUNOLOGY (2008)
Increased expression of monocarboxylate transporters 1, 2, and 4 in colorectal carcinomas
Celine Pinheiro et al.
VIRCHOWS ARCHIV (2008)
Acidic extracellular pH increases calcium influx-triggered phospholipase D activity along with acidic sphingomyelinase activation to induce matrix metalloproteinase-9 expression in mouse metastatic melanoma
Yasumasa Kato et al.
FEBS JOURNAL (2007)
The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1α-dependent mechanism
MS Ullah et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
JW Kim et al.
CELL METABOLISM (2006)
Lactate physiology in health and disease
Barrie Phypers et al.
BJA EDUCATION (2006)
Reversible inactivation of HIF-1 prolyl hydroxylases allows cell metabolism to control basal HIF-1
HS Lu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Lactate: Mirror and motor of tumor malignancy
S Walenta et al.
SEMINARS IN RADIATION ONCOLOGY (2004)
Metabolic classification of human rectal adenocarcinomas: a novel guideline for clinical oncologists?
S Walenta et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2003)
No evidence of an intracellular lactate shuttle in rat skeletal muscle
K Sahlin et al.
JOURNAL OF PHYSIOLOGY-LONDON (2002)
Lactate stimulates fibroblast expression of hyaluronan and CD44: The Warburg effect revisited
R Stern et al.
EXPERIMENTAL CELL RESEARCH (2002)
分享论文
