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Atsushi Nakamura et al.
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B W Higgs et al.
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Aaron M. Goodman et al.
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Daniel S. Chen et al.
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Collin M. Blakely et al.
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D. P. Carbone et al.
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Isidro Cortes-Ciriano et al.
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Correlation of tumor mutation burden and chemotherapy outcomes in colorectal cancer
Sachin G. Pai et al.
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Peter M. Scarbrough et al.
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David A. Braun et al.
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Jeffrey C. Thompson et al.
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Predictive biomarkers for checkpoint inhibitor-based immunotherapy
Geoffrey T. Gibney et al.
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Axel Hoos
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William D. Travis et al.
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Sang Yun Ha et al.
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Caicun Zhou et al.
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New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)
E. A. Eisenhauer et al.
EUROPEAN JOURNAL OF CANCER (2009)