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miRNA-29b Suppresses Prostate Cancer Metastasis by Regulating Epithelial-Mesenchymal Transition Signaling
Peng Ru et al.
MOLECULAR CANCER THERAPEUTICS (2012)
Expression of GLUT1 and GLUT3 Glucose Transporters in Endometrial and Breast Cancers
Anna Krzeslak et al.
PATHOLOGY & ONCOLOGY RESEARCH (2012)
Foxa1 Reduces Lipid Accumulation in Human Hepatocytes and Is Down-Regulated in Nonalcoholic Fatty Liver
Marta Moya et al.
PLOS ONE (2012)
A Novel Network Integrating a miRNA-203/SNAI1 Feedback Loop which Regulates Epithelial to Mesenchymal Transition
Michele Moes et al.
PLOS ONE (2012)
Differential Expression of MicroRNAs in Adipose Tissue after Long-Term High-Fat Diet-Induced Obesity in Mice
Dionysios V. Chartoumpekis et al.
PLOS ONE (2012)
Epithelial Mesenchymal Transition and Pancreatic Tumor Initiating CD44+/EpCAM+ Cells Are Inhibited by γ-Secretase Inhibitor IX
Vindhya Palagani et al.
PLOS ONE (2012)
De-Meaning of Metabolism
Mitchell A. Lazar et al.
SCIENCE (2012)
Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation
Mohit Jain et al.
SCIENCE (2012)
A tale with a Twist: a developmental gene with potential relevance for metabolic dysfunction and inflammation in adipose tissue
Anca D. Dobrian
Frontiers in Endocrinology (2012)
Epithelial to Mesenchymal Transition Is a Determinant of Sensitivity to Chemoradiotherapy in Non-Small Cell Lung Cancer
Yasushi Shintani et al.
ANNALS OF THORACIC SURGERY (2011)
The ins and Outs of the Epithelial to Mesenchymal Transition in Health and Disease
M. Angela Nieto
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 27 (2011)
Phosphoglucose Isomerase/Autocrine Motility Factor Mediates Epithelial-Mesenchymal Transition Regulated by miR-200 in Breast Cancer Cells
Aamir Ahmad et al.
CANCER RESEARCH (2011)
Phosphorylation of Serine 68 of Twist1 by MAPKs Stabilizes Twist1 Protein and Promotes Breast Cancer Cell Invasiveness
Jun Hong et al.
CANCER RESEARCH (2011)
miR-34 and SNAIL form a double-negative feedback loop to regulate epithelial-mesenchymal transitions
Helge Siemens et al.
CELL CYCLE (2011)
Tracking the intermediate stages of epithelial-mesenchymal transition in epithelial stem cells and cancer
Nicole Vincent Jordan et al.
CELL CYCLE (2011)
The Adipocyte-Expressed Forkhead Transcription Factor Foxc2 Regulates Metabolism Through Altered Mitochondrial Function
Martin E. Lidell et al.
DIABETES (2011)
The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells
Simone Brabletz et al.
EMBO JOURNAL (2011)
Withaferin A inhibits breast cancer invasion and metastasis at sub-cytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation
Jose T. Thaiparambil et al.
INTERNATIONAL JOURNAL OF CANCER (2011)
Functional Cooperation between Snail1 and Twist in the Regulation of ZEB1 Expression during Epithelial to Mesenchymal Transition
Natlia Dave et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
p53 regulates epithelial-mesenchymal transition through microRNAs targeting ZEB1 and ZEB2
Taewan Kim et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Redundant or separate entities?-roles of Twist1 and Twist2 as molecular switches during gene transcription
Hector L. Franco et al.
NUCLEIC ACIDS RESEARCH (2011)
KLF8 promotes human breast cancer cell invasion and metastasis by transcriptional activation of MMP9
X. Wang et al.
ONCOGENE (2011)
Proteomics characterization of gastrokine 1-induced growth inhibition of gastric cancer cells
Guang-Rong Yan et al.
PROTEOMICS (2011)
A Perspective on Cancer Cell Metastasis
Christine L. Chaffer et al.
SCIENCE (2011)
Loss of FOXA1/2 Is Essential for the Epithelial-to-Mesenchymal Transition in Pancreatic Cancer
Yan Song et al.
CANCER RESEARCH (2010)
R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer
Sacha J. Holland et al.
CANCER RESEARCH (2010)
The transcription factor grainyhead-like 2 regulates the molecular composition of the epithelial apical junctional complex
Max Werth et al.
DEVELOPMENT (2010)
ENO1, a potential prognostic head and neck cancer marker, promotes transformation partly via chemokine CCL20 induction
Sen-Tien Tsai et al.
EUROPEAN JOURNAL OF CANCER (2010)
GATA3 Inhibits Breast Cancer Metastasis through the Reversal of Epithelial-Mesenchymal Transition
Wei Yan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Isocitrate Dehydrogenase 1 and 2 Mutations in Cancer: Alterations at a Crossroads of Cellular Metabolism
Zachary J. Reitman et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2010)
Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model
Li Ma et al.
NATURE BIOTECHNOLOGY (2010)
miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis
Li Ma et al.
NATURE CELL BIOLOGY (2010)
Monoclonal antibody targeting of N-cadherin inhibits prostate cancer growth, metastasis and castration resistance
Hiroshi Tanaka et al.
NATURE MEDICINE (2010)
Snail expression is an independent predictor of tumor recurrence in superficial bladder cancers
Franck Bruyere et al.
UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS (2010)
An emerging role for class I bHLH E2-2 proteins in EMT regulation and tumor progression
Amparo Cano et al.
CELL ADHESION & MIGRATION (2010)
Stabilization of Snail by NF-κB Is Required for Inflammation-Induced Cell Migration and Invasion
Yadi Wu et al.
CANCER CELL (2009)
Up-regulation of miR-200 and let-7 by Natural Agents Leads to the Reversal of Epithelial-to-Mesenchymal Transition in Gemcitabine-Resistant Pancreatic Cancer Cells
Yiwei Li et al.
CANCER RESEARCH (2009)
Epithelial-Mesenchymal Transitions in Development and Disease
Jean Paul Thiery et al.
CELL (2009)
High expression of Snail mRNA in blood from hepatocellular carcinoma patients with extra-hepatic metastasis
Ae Lyoung Min et al.
CLINICAL & EXPERIMENTAL METASTASIS (2009)
A developmentally regulated inducer of EMT, LBX1, contributes to breast cancer progression
Min Yu et al.
GENES & DEVELOPMENT (2009)
Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression
Don L. Gibbons et al.
GENES & DEVELOPMENT (2009)
Small C-terminal Domain Phosphatase Enhances Snail Activity through Dephosphorylation
Yadi Wu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
The class I bHLH factors E2-2A and E2-2B regulate EMT
Veronica R. Sobrado et al.
JOURNAL OF CELL SCIENCE (2009)
Biomarkers for epithelial-mesenchymal transitions
Michael Zeisberg et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
The basics of epithelial-mesenchymal transition
Raghu Kalluri et al.
JOURNAL OF CLINICAL INVESTIGATION (2009)
The triad of paragangliomas, gastric stromal tumours and pulmonary chondromas (Carney triad), and the dyad of paragangliomas and gastric stromal sarcomas (Carney-Stratakis syndrome): molecular genetics and clinical implications
C. A. Stratakis et al.
JOURNAL OF INTERNAL MEDICINE (2009)
HIF-1 alpha Modulates Energy Metabolism in Cancer Cells by Inducing Over-Expression of Specific Glycolytic Isoforms
Alvaro Marin-Hernandez et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2009)
Downregulated MicroRNA-200a in Meningiomas Promotes Tumor Growth by Reducing E-Cadherin and Activating the Wnt/β-Catenin Signaling Pathway
Okay Saydam et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Recurring Mutations Found by Sequencing an Acute Myeloid Leukemia Genome
Elaine R. Mardis et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
IDH1 and IDH2 Mutations in Gliomas
Hai Yan et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Meta-regulation: microRNA regulation of glucose and lipid metabolism
Francis C. Lynn
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2009)
Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits
Kornelia Polyak et al.
NATURE REVIEWS CANCER (2009)
The transcriptional repressor ZEB1 promotes metastasis and loss of cell polarity in cancer
Simone Spaderna et al.
CANCER RESEARCH (2008)
The epithelial-mesenchymal transition generates cells with properties of stem cells
Sendurai A. Mani et al.
CELL (2008)
Epithelial-mesenchymal transition: At the crossroads of development and tumor metastasis
Jing Yang et al.
DEVELOPMENTAL CELL (2008)
A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cells
Ulrike Burk et al.
EMBO REPORTS (2008)
A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial-mesenchymal transition
Manuel Beltran et al.
GENES & DEVELOPMENT (2008)
The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
Sun-Mi Park et al.
GENES & DEVELOPMENT (2008)
The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2
Manav Korpal et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Polycomb complex 2 is required for E-cadherin repression by the snail1 transcription factor
Nicolas Herranz et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
Erk5 Controls Slug Expression and Keratinocyte Activation during Wound Healing
Valerie Arnoux et al.
MOLECULAR BIOLOGY OF THE CELL (2008)
A novel inhibitor of glucose uptake sensitizes cells to FAS-induced cell death
Tabitha E. Wood et al.
MOLECULAR CANCER THERAPEUTICS (2008)
The mir-200 family and mir-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1
Philip A. Gregory et al.
NATURE CELL BIOLOGY (2008)
The transcription factor snail represses Crumbs3 expression and disrupts apico-basal polarity complexes
E. L. Whiteman et al.
ONCOGENE (2008)
Generation of Breast Cancer Stem Cells through Epithelial-Mesenchymal Transition
Anne-Pierre Morel et al.
PLOS ONE (2008)
The E-cadherin repressor Snail is associated with lower overall survival of ovarian cancer patients
K. Blechschmidt et al.
BRITISH JOURNAL OF CANCER (2008)
Tumour invasion and metastasis initiated by microRNA 10b in breast cancer
Li Ma et al.
NATURE (2007)
Epidermal growth factor receptor cooperates with signal transducer and activator of transcription 3 to induce epithelial-mesenchymal transition in cancer cells via up-regulation of TWIST gene expression
Hui-Wen Lo et al.
CANCER RESEARCH (2007)
The transcription factor ZEB1 (δEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity
K. Aigner et al.
ONCOGENE (2007)
Snail family transcription factors are implicated in thyroid carcinogenesis
Robert G. Hardy et al.
AMERICAN JOURNAL OF PATHOLOGY (2007)
Epithelial to mesenchymal transition: Expression of the regulators snail, slug, and twist in pancreatic cancer
Birgit Hotz et al.
CLINICAL CANCER RESEARCH (2007)
Kruppel-like factor 8 induces epithelial to mesenchymal transition and epithelial cell invasion
Xianhui Wang et al.
CANCER RESEARCH (2007)
Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers
Sendurai A. Mani et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Snail, ZEB and bHLH factors in tumour progression: an alliance against the epithelial phenotype?
Hector Peinado et al.
NATURE REVIEWS CANCER (2007)
Wnt-dependent de novo hair follicle regeneration in adult mouse skin after wounding
Mayumi Ito et al.
NATURE (2007)
Down-regulation of phosphoglucose isomerase/autocrine motility factor results in mesenchymal-to-epithelial transition of human lung fibrosarcoma cells
Tatsuyoshi Funasaka et al.
CANCER RESEARCH (2007)
miR-21-mediated tumor growth
M.-L. Si et al.
ONCOGENE (2007)
The Spemann organizer gene, Goosecoid, promotes tumor metastasis
Kimberly A. Hartwell et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
A Wnt-Axin2-GSK3β cascade regulates Snail1 activity in breast cancer cells
Jong In Yook et al.
NATURE CELL BIOLOGY (2006)
Snail activation disrupts tissue homeostasis and induces fibrosis in the adult kidney
Agnes Boutet et al.
EMBO JOURNAL (2006)
Identification of α-enolase as an autoantigen in lung cancer:: Its overexpression is associated with clinical outcomes
Gee-Chen Chang et al.
CLINICAL CANCER RESEARCH (2006)
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
Kazutoshi Takahashi et al.
CELL (2006)
Increased lipogenesis in cancer cells: new players, novel targets
Johannes V. Swinnen et al.
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2006)
Slug expression is an independent prognostic parameter for poor survival in colorectal carcinoma patients
M. Shioiri et al.
BRITISH JOURNAL OF CANCER (2006)
Reassessing epithelial to mesenchymal transition as a prerequisite for carcinoma invasion and metastasis
Jason J. Christiansen et al.
CANCER RESEARCH (2006)
ATP citrate lyase inhibition can suppress tumor cell growth
G Hatzivassiliou et al.
CANCER CELL (2005)
The fallacy of epithelial mesenchymal transition in neoplasia
D Tarin
CANCER RESEARCH (2005)
The Snail genes as inducers of cell movement and survival: implications in development and cancer
A Barrallo-Gimeno et al.
DEVELOPMENT (2005)
Fumarate hydratase mutations and predisposition to cutaneous leiomyomas, uterine leiomyomas and renal cancer
NA Alam et al.
BRITISH JOURNAL OF DERMATOLOGY (2005)
A specific inhibitor of TGF-β receptor kinase, SB-431542, as a potent antitumor agent for human cancers
SK Halder et al.
NEOPLASIA (2005)
Pak1 phosphorylation of snail, a master regulator of epithelial-to-mesenchyme transition, modulates snail's subcellular localization and functions
ZB Yang et al.
CANCER RESEARCH (2005)
DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells
A Eger et al.
ONCOGENE (2005)
Wnt-dependent regulation of the E-cadherin repressor snail
JI Yook et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Transient overexpression of TGF-β1 induces epithelial mesenchymal transition in the rodent peritoneum
PJ Margetts et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2005)
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
BP Lewis et al.
CELL (2005)
Glycogen synthase kinase-3 is an endogenous inhibitor of snail transcription: implications for the epithelial-mesenchymal transition
RE Bachelder et al.
JOURNAL OF CELL BIOLOGY (2005)
A signaling pathway involving TGF-beta 2 and snail in hair follicle morphogenesis
C Jamora et al.
PLOS BIOLOGY (2005)
MicroRNAs: Genomics, biogenesis, mechanism, and function
DP Bartel
CELL (2004)
Snail family members and cell survival in physiological and pathological cleft palates
C Martinez-Alvarez et al.
DEVELOPMENTAL BIOLOGY (2004)
Phosphorylation regulates the subcellular location and activity of the snail transcriptional repressor
D Domínguez et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins
AA Postigo et al.
EMBO JOURNAL (2003)
MTA3, a Mi-2/NuRD complex subunit, an invasive growth pathway in breast
N Fujita et al.
CELL (2003)
Mice lacking Zfhx1b, the gene that codes for Smad- interacting protein-1, reveal a role for multiple neural crest cell defects in the etiology of Hirschsprung disease-mental retardation syndrome
T Van de Putte et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2003)
The zinc finger/homeodomain protein δEF1 mediates estrogen-specific induction of the ovalbumin gene
NB Dillner et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2002)
FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance
A Cederberg et al.
CELL (2001)
Snail/Slug family of repressors: slowly going into the fast lane of development and cancer
K Hemavathy et al.
GENE (2000)
Identification of a novel FAS/ER-α fusion transcript expressed in human cancer cells
QN Ye et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION (2000)
Slug is an essential target of TGFβ2 signaling in the developing chicken heart
LA Romano et al.
DEVELOPMENTAL BIOLOGY (2000)
Differential expression and function of members of the zfh-1 family of zinc finger/homeodomain repressors
AA Postigo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
The transcription factor Snail is a repressor of E-cadherin gene expression in epithelial tumour cells
E Batlle et al.
NATURE CELL BIOLOGY (2000)
Minimal phenotype of mice homozygous for a null mutation in the forkhead/winged helix gene, Mf2
T Kume et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
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