相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Autism-like social deficit generated by Dock4 deficiency is rescued by restoration of Rac1 activity and NMDA receptor function
Daji Guo et al.
MOLECULAR PSYCHIATRY (2021)
Opposite Modulation of RAC1 by Mutations in TRIO Is Associated with Distinct, Domain-Specific Neurodevelopmental Disorders
Sonia Barbosa et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2020)
Two Autism/Dyslexia Linked Variations of DOCK4 Disrupt the Gene Function on Rac1/Rap1 Activation, Neurite Outgrowth, and Synapse Development
Miaoqi Huang et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2020)
DOCK family proteins: key players in immune surveillance mechanisms
Kazufumi Kunimura et al.
INTERNATIONAL IMMUNOLOGY (2020)
Autism spectrum disorder in females with ARHGEF9 alterations and a random pattern of X chromosome inactivation
Mahmoud Aarabi et al.
EUROPEAN JOURNAL OF MEDICAL GENETICS (2019)
De novo single-nucleotide and copy number variation in discordant monozygotic twins reveals disease-related genes
Nirmal Vadgama et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2019)
Regulators of Rho GTPases in the Nervous System: Molecular Implication in Axon Guidance and Neurological Disorders
Sadig Niftullayev et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Autism and Schizophrenia-Associated CYFIP1 Regulates the Balance of Synaptic Excitation and Inhibition
Elizabeth C. Davenport et al.
CELL REPORTS (2019)
Trio Haploinsufficiency Causes Neurodevelopmental Disease-Associated Deficits
Sara Marie Katrancha et al.
CELL REPORTS (2019)
The influence of neuroinflammation in Autism Spectrum Disorder
Samantha M. Matta et al.
BRAIN BEHAVIOR AND IMMUNITY (2019)
Neurological Diseases With Autism Spectrum Disorder: Role of ASD Risk Genes
Juan Xiong et al.
FRONTIERS IN NEUROSCIENCE (2019)
p190RhoGAPs, the ARHGAP35-and ARHGAP5-Encoded Proteins, in Health and Disease
Capucine Heraud et al.
CELLS (2019)
DOCK8 is expressed in microglia, and it regulates microglial activity during neurodegeneration in murine disease models
Kazuhiko Namekata et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
The autism- and schizophrenia-associated protein CYFIP1 regulates bilateral brain connectivity and behaviour
Nuria Dominguez-Iturza et al.
NATURE COMMUNICATIONS (2019)
Cyfip1 haploinsufficient rats show white matter changes, myelin thinning, abnormal oligodendrocytes and behavioural inflexibility
Ana Silva et al.
NATURE COMMUNICATIONS (2019)
CYFIP1 overexpression increases fear response in mice but does not affect social or repetitive behavioral phenotypes
Catherine Fricano-Kugler et al.
MOLECULAR AUTISM (2019)
Inherited and De Novo Genetic Risk for Autism Impacts Shared Networks
Elizabeth K. Ruzzo et al.
CELL (2019)
Characterization of intellectual disability and autism comorbidity through gene panel sequencing
Maria C. Aspromonte et al.
HUMAN MUTATION (2019)
Genome sequencing identifies multiple deleterious variants in autism patients with more severe phenotypes
Hui Guo et al.
GENETICS IN MEDICINE (2019)
OCRL deficiency impairs endolysosomal function in a humanized mouse model for Lowe syndrome and Dent disease
Beatrice Paola Festa et al.
HUMAN MOLECULAR GENETICS (2019)
Behavioral training rescues motor deficits in Cyfip1 haploinsufficiency mouse model of autism spectrum disorders
Sven O. Bachmann et al.
TRANSLATIONAL PSYCHIATRY (2019)
Prevalence of co-occurring mental health diagnoses in the autism population: a systematic review and meta-analysis
Meng-Chuan Lai et al.
LANCET PSYCHIATRY (2019)
Rho GTPase signaling complexes in cell migration and invasion
Campbell D. Lawson et al.
JOURNAL OF CELL BIOLOGY (2018)
Biochemical and Morphological Characterization of a Guanine Nucleotide Exchange Factor ARHGEF9 in Mouse Tissues
Kyoko Ibaraki et al.
ACTA HISTOCHEMICA ET CYTOCHEMICA (2018)
De Novo Truncating Mutations in WASF1 Cause Intellectual Disability with Seizures
Yoko Ito et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2018)
Rho GTPases in Intellectual Disability: From Genetics to Therapeutic Opportunities
Valentina Zamboni et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Cytoplasmic FMRP interacting protein 1/2 (CYFIP1/2) expression analysis in autism
Rezvan Noroozi et al.
METABOLIC BRAIN DISEASE (2018)
Dendritic spine actin cytoskeleton in autism spectrum disorder
Merja Joensuu et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2018)
Rare structural variants in the DOCK8 gene identified in a cohort of 439 patients with neurodevelopmental disorders
Danijela Krgovic et al.
SCIENTIFIC REPORTS (2018)
Integrative Analyses of De Novo Mutations Provide Deeper Biological Insights into Autism Spectrum Disorder
Atsushi Takata et al.
CELL REPORTS (2018)
Impairment of social behaviors in Arhgef10 knockout mice
Dai-Hua Lu et al.
MOLECULAR AUTISM (2018)
Synaptic Plasticity and Excitation-Inhibition Balance in the Dentate Gyrus: Insights from In Vivo Recordings in Neuroligin-1, Neuroligin-2, and Collybistin Knockouts
Peter Jedlicka et al.
NEURAL PLASTICITY (2018)
The Autism-Related Protein PX-RICS Mediates GABAergic Synaptic Plasticity in Hippocampal Neurons and Emotional Learning in Mice
Tsutomu Nakamura et al.
EBIOMEDICINE (2018)
PAK2 Haploinsufficiency Results in Synaptic Cytoskeleton Impairment and Autism-Related Behavior
Yan Wang et al.
CELL REPORTS (2018)
Inherited and multiple de novo mutations in autism/developmental delay risk genes suggest a multifactorial model
Hui Guo et al.
MOLECULAR AUTISM (2018)
Prevalence of Autism Spectrum Disorder Among Children Aged 8 Years - Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2014
Jon Baio et al.
MMWR SURVEILLANCE SUMMARIES (2018)
The Evolutionary Landscape of Dbl-Like RhoGEF Families: Adapting Eukaryotic Cells to Environmental Signals
Philippe Fort et al.
GENOME BIOLOGY AND EVOLUTION (2017)
Protein Kinase A Deregulation in the Medial Prefrontal Cortex Impairs Working Memory in Murine Oligophrenin-1 Deficiency
Chun-Lei Zhang et al.
JOURNAL OF NEUROSCIENCE (2017)
Rho GTPase-activating proteins: Regulators of Rho GTPase activity in neuronal development and CNS diseases
Guo-Hui Huang et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2017)
Targeted sequencing and functional analysis reveal brain-size-related genes and their networks in autism spectrum disorders
Jinchen Li et al.
MOLECULAR PSYCHIATRY (2017)
Targeted sequencing identifies 91 neurodevelopmental-disorder risk genes with autism and developmental-disability biases
Holly A. F. Stessman et al.
NATURE GENETICS (2017)
Hotspots of missense mutation identify neurodevelopmental disorder genes and functional domains
Madeleine R. Geisheker et al.
NATURE NEUROSCIENCE (2017)
Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder
Ryan K. C. Yuen et al.
NATURE NEUROSCIENCE (2017)
WAVE1 in neurons expressing the D1 dopamine receptor regulates cellular and behavioral actions of cocaine
Ilaria Ceglia et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
p190RhoGAP proteins contain pseudoGTPase domains
Amy L. Stiegler et al.
NATURE COMMUNICATIONS (2017)
p190-B RhoGAP and intracellular cytokine signals balance hematopoietic stem and progenitor cell self-renewal and differentiation
Ashwini Hinge et al.
NATURE COMMUNICATIONS (2017)
An autism spectrum disorder-related de novo mutation hotspot discovered in the GEF1 domain of Trio
Anastasiia Sadybekov et al.
NATURE COMMUNICATIONS (2017)
Rho GTPases as therapeutic targets in Alzheimer's disease
Byron J. Aguilar et al.
ALZHEIMERS RESEARCH & THERAPY (2017)
Copy number variation meta-analysis reveals a novel duplication at 9p24 associated with multiple neurodevelopmental disorders
Joseph T. Glessner et al.
GENOME MEDICINE (2017)
RhoGEF9 splice isoforms influence neuronal maturation and synapse formation downstream of α2 GABAA receptors
Claire de Groot et al.
PLOS GENETICS (2017)
ARHGEF9 disease Phenotype clarification and genotype-phenotype correlation
Michael Alber et al.
NEUROLOGY-GENETICS (2017)
Novel gene function and regulation in neocortex expansion
Michael Heide et al.
CURRENT OPINION IN CELL BIOLOGY (2017)
Autism spectrum disorder: neuropathology and animal models
Merina Varghese et al.
ACTA NEUROPATHOLOGICA (2017)
RAC1 Missense Mutations in Developmental Disorders with Diverse Phenotypes
Margot R. F. Reijnders et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2017)
DOCK8 deficiency: Insights into pathophysiology, clinical features and management
Catherine M. Biggs et al.
CLINICAL IMMUNOLOGY (2017)
Novel Unbalanced Translocations Affecting the Long Arms of Chromosomes 10 and 22 Cause Complex Syndromes with Very Severe Neurodevelopmental Delay, Speech Impairment, Autistic Behavior, and Epilepsy
Emanuele G. Coci et al.
CYTOGENETIC AND GENOME RESEARCH (2017)
Loss of Either Rac1 or Rac3 GTPase Differentially Affects the Behavior of Mutant Mice and the Development of Functional GABAergic Networks
Roberta Pennucci et al.
CEREBRAL CORTEX (2016)
Collybistin binds and inhibits mTORC1 signaling: a potential novel mechanism contributing to intellectual disability and autism
Camila Oliveira Freitas Machado et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2016)
Heritability of autism spectrum disorders: a meta-analysis of twin studies
Beata Tick et al.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY (2016)
Genome Sequencing of Autism-Affected Families Reveals Disruption of Putative Noncoding Regulatory DNA
Tychele N. Turner et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2016)
Novel features of 3q29 deletion syndrome: Results from the 3q29 registry
Megan R. Glassford et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2016)
Recurrent 15q11.2 BP1-BP2 Microdeletions and Microduplications in the Etiology of Neurodevelopmental Disorders
Chiara Picinelli et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2016)
Morphological and behavioral characterization of adult mice deficient for SrGAP3
Jonathan Bertram et al.
CELL AND TISSUE RESEARCH (2016)
Neocortex expansion in development and evolution - from cell biology to single genes
Michaela Wilsch-Braeuninger et al.
CURRENT OPINION IN NEUROBIOLOGY (2016)
Xq11.1-11.2 deletion involving ARHGEF9 in a girl with autism spectrum disorder
Gifty Bhat et al.
EUROPEAN JOURNAL OF MEDICAL GENETICS (2016)
Oligophrenin-1 regulates number, morphology and synaptic properties of adult-born inhibitory interneurons in the olfactory bulb
Nelly Redolfi et al.
HUMAN MOLECULAR GENETICS (2016)
Fasudil treatment in adult reverses behavioural changes and brain ventricular enlargement in Oligophrenin-1 mouse model of intellectual disability
Hamid Meziane et al.
HUMAN MOLECULAR GENETICS (2016)
Deciphering the Molecular and Functional Basis of RHOGAP Family Proteins: A SYSTEMATIC APPROACH TOWARD SELECTIVE INACTIVATION OF RHO FAMILY PROTEINS
Ehsan Amin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Cyfip1 Regulates Presynaptic Activity during Development
Kuangfu Hsiao et al.
JOURNAL OF NEUROSCIENCE (2016)
Comprehensive molecular testing in patients with high functioning autism spectrum disorder
Maria Isabel Alvarez-Mora et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2016)
Regulating Rho GTPases and their regulators
Richard G. Hodge et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2016)
IRSp53/BAIAP2 in dendritic spine development, NMDA receptor regulation, and psychiatric disorders
Jaeseung Kang et al.
NEUROPHARMACOLOGY (2016)
Astrocytes and Microglia and Their Potential Link with Autism Spectrum Disorders
Francesco Petrelli et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2016)
PX-RICS-deficient mice mimic autism spectrum disorder in Jacobsen syndrome through impaired GABAA receptor trafficking
Tsutomu Nakamura et al.
NATURE COMMUNICATIONS (2016)
De novo genic mutations among a Chinese autism spectrum disorder cohort
Tianyun Wang et al.
NATURE COMMUNICATIONS (2016)
MYO9B gene polymorphisms are associated with the risk of inflammatory bowel diseases
Ming-Jie Wang et al.
ONCOTARGET (2016)
The Contribution of Mosaic Variants to Autism Spectrum Disorder
Donald Freed et al.
PLOS GENETICS (2016)
MicroRNA-132 Interact with p250GAP/Cdc42 Pathway in the Hippocampal Neuronal Culture Model of Acquired Epilepsy and Associated with Epileptogenesis Process
Jinxian Yuan et al.
NEURAL PLASTICITY (2016)
A pilot study on commonality and specificity of copy number variants in schizophrenia and bipolar disorder
J. Chen et al.
TRANSLATIONAL PSYCHIATRY (2016)
A single splice site mutation in human-specific ARHGAP11B causes basal progenitor amplification
Marta Florio et al.
SCIENCE ADVANCES (2016)
Common Regulatory Variants of CYFIP1 Contribute to Susceptibility for Autism Spectrum Disorder (ASD) and Classical Autism
Jian Wang et al.
ANNALS OF HUMAN GENETICS (2015)
Parental origin impairment of synaptic functions and behaviors in cytoplasmic FMRP interacting protein 1 (Cyfip1) deficient mice
Leeyup Chung et al.
BRAIN RESEARCH (2015)
Trio gene is required for mouse learning ability
Wen Zong et al.
BRAIN RESEARCH (2015)
A single PXXP motif in the C-terminal region of srGAP3 mediates binding to multiple SH3 domains
Silvia Wuertenberger et al.
FEBS LETTERS (2015)
Fragile X mental retardation protein (FMRP) interacting proteins exhibit different expression patterns during development
C. M. Bonaccorso et al.
INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE (2015)
The 15q11.2 BP1-BP2 Microdeletion Syndrome: A Review
Devin M. Cox et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)
From the genetic architecture to synaptic plasticity in autism spectrum disorder
Thomas Bourgeron
NATURE REVIEWS NEUROSCIENCE (2015)
Rac1 plays an essential role in axon growth and guidance and in neuronal survival in the central and peripheral nervous systems
Zhong L. Hua et al.
NEURAL DEVELOPMENT (2015)
Low load for disruptive mutations in autism genes and their biased transmission
Ivan Iossifov et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Synaptic P-Rex1 signaling regulates hippocampal long-term depression and autism-like social behavior
Jun Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion
Marta Florio et al.
SCIENCE (2015)
Regulating Rac in the Nervous System: Molecular Function and Disease Implication of Rac GEFs and GAPs
Yanyang Bai et al.
BIOMED RESEARCH INTERNATIONAL (2015)
Heritability of Autism Spectrum Disorder in a UK Population-Based Twin Sample
Emma Colvert et al.
JAMA PSYCHIATRY (2015)
Targeted massively parallel sequencing of autism spectrum disorder-associated genes in a case control cohort reveals rare loss-of-function risk variants
Anthony J. Griswold et al.
MOLECULAR AUTISM (2015)
Evidence for autism spectrum disorder in Jacobsen syndrome: identification of a candidate gene in distal 11q
Natacha Akshoomoff et al.
GENETICS IN MEDICINE (2015)
Common variants in genes of the postsynaptic FMRP signalling pathway are risk factors for autism spectrum disorders
Regina Waltes et al.
HUMAN GENETICS (2014)
Dendritic Cell Motility and T Cell Activation Requires Regulation of Rho-Cofilin Signaling by the Rho-GTPase Activating Protein Myosin IXb
Yan Xu et al.
JOURNAL OF IMMUNOLOGY (2014)
Family-based association study of ZNF533, DOCK4 and IMMP2L gene polymorphisms linked to autism in a northeastern Chinese Han population
Shuang Liang et al.
JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B (2014)
Exome sequencing in multiplex autism families suggests a major role for heterozygous truncating mutations
C. Toma et al.
MOLECULAR PSYCHIATRY (2014)
Synaptic, transcriptional and chromatin genes disrupted in autism
Silvia De Rubeis et al.
NATURE (2014)
The contribution of de novo coding mutations to autism spectrum disorder
Ivan Iossifov et al.
NATURE (2014)
Oligophrenin-1 (OPHN1), a Gene Involved in X-Linked Intellectual Disability, Undergoes RNA Editing and Alternative Splicing during Human Brain Development
Sabina Barresi et al.
PLOS ONE (2014)
Lack of the presynaptic RhoGAP protein oligophrenin1 leads to cognitive disabilities through dysregulation of the cAMP/PKA signalling pathway
Malik Khelfaoui et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2014)
Dock GEFs and their therapeutic potential: Neuroprotection and axon regeneration
Kazuhiko Namekata et al.
PROGRESS IN RETINAL AND EYE RESEARCH (2014)
Rho family GTPases: key players in neuronal development neuronal survival, and neurodegeneration
Trisha R. Stankiewicz et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2014)
The autism and schizophrenia associated gene CYFIP1 is critical for the maintenance of dendritic complexity and the stabilization of mature spines
M. Pathania et al.
TRANSLATIONAL PSYCHIATRY (2014)
Myo9b and RICS Modulate Dendritic Morphology of Cortical Neurons
Hui Long et al.
CEREBRAL CORTEX (2013)
Dysfunction of SHANK2 and CHRNA7 in a patient with intellectual disability and language impairment supports genetic epistasis of the two loci
B. Chiliana et al.
CLINICAL GENETICS (2013)
Immune regulatory functions of DOCK family proteins in health and disease
Akihiko Nishikimi et al.
EXPERIMENTAL CELL RESEARCH (2013)
The Atypical Guanine Nucleotide Exchange Factor Dock4 Regulates Neurite Differentiation through Modulation of Rac1 GTPase and Actin Dynamics
Yangui Xiao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Type 1 Inositol Trisphosphate Receptor Regulates Cerebellar Circuits by Maintaining the Spine Morphology of Purkinje Cells in Adult Mice
Takeyuki Sugawara et al.
JOURNAL OF NEUROSCIENCE (2013)
Neuronal Rac1 Is Required for Learning-Evoked Neurogenesis
Ursula Haditsch et al.
JOURNAL OF NEUROSCIENCE (2013)
p190-B RhoGAP regulates the functional composition of the mesenchymal microenvironment
R. Raman et al.
LEUKEMIA (2013)
Activity-dependent neuronal signalling and autism spectrum disorder
Daniel H. Ebert et al.
NATURE (2013)
Progress toward treatments for synaptic defects in autism
Richard Delorme et al.
NATURE MEDICINE (2013)
The cellular function of srGAP3 and its role in neuronal morphogenesis
Claire Bacon et al.
MECHANISMS OF DEVELOPMENT (2013)
CYFIP1 Coordinates mRNA Translation and Cytoskeleton Remodeling to Ensure Proper Dendritic Spine Formation
Silvia De Rubeis et al.
NEURON (2013)
The Inverse F-BAR Domain Protein srGAP2 Acts through srGAP3 to Modulate Neuronal Differentiation and Neurite Outgrowth of Mouse Neuroblastoma Cells
Yue Ma et al.
PLOS ONE (2013)
IP3R1 deficiency in the cerebellum/brainstem causes basal ganglia-independent dystonia by triggering tonic Purkinje cell firings in mice
Chihiro Hisatsune et al.
FRONTIERS IN NEURAL CIRCUITS (2013)
Prevalence of autism in mainland China, Hong Kong and Taiwan: a systematic review and meta-analysis
Xiang Sun et al.
MOLECULAR AUTISM (2013)
SFARI Gene 2.0: a community-driven knowledgebase for the autism spectrum disorders (ASDs)
Brett S. Abrahams et al.
MOLECULAR AUTISM (2013)
Duplication of OCRL and Adjacent Genes Associated With Autism but not Lowe Syndrome
Richard J. Schroer et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2012)
Global Prevalence of Autism and Other Pervasive Developmental Disorders
Mayada Elsabbagh et al.
AUTISM RESEARCH (2012)
DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses
Yosuke Harada et al.
BLOOD (2012)
Rac1-Dependent Cell Cycle Exit of MGE Precursors and GABAergic Interneuron Migration to the Cortex
Marina Vidaki et al.
CEREBRAL CORTEX (2012)
Srgap3-/- mice present a neurodevelopmental disorder with schizophrenia-related intermediate phenotypes
Robert Waltereit et al.
FASEB JOURNAL (2012)
De Novo Gene Disruptions in Children on the Autistic Spectrum
Ivan Iossifov et al.
NEURON (2012)
Haploinsufficiency of Cyfip1 Produces Fragile X-Like Phenotypes in Mice
Ozlem Bozdagi et al.
PLOS ONE (2012)
Genetic and Functional Analyses of SHANK2 Mutations Suggest a Multiple Hit Model of Autism Spectrum Disorders
Claire S. Leblond et al.
PLOS GENETICS (2012)
The Rising Prevalence of Autism: A Prospective Longitudinal Study in the Faroe Islands
Eva Kocovska et al.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS (2012)
Prevalence of Autism Spectrum Disorders in a Total Population Sample
Young Shin Kim et al.
AMERICAN JOURNAL OF PSYCHIATRY (2011)
Use of array CGH to detect exonic copy number variants throughout the genome in autism families detects a novel deletion in TMLHE
Patricia B. S. Celestino-Soper et al.
HUMAN MOLECULAR GENETICS (2011)
The RhoG/ELMO1/Dock180 Signaling Module Is Required for Spine Morphogenesis in Hippocampal Neurons
Jeong-Yoon Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Identification of a Negative Regulatory Region for the Exchange Activity and Characterization of T332I Mutant of Rho Guanine Nucleotide Exchange Factor 10 (ARHGEF10)
Taro Chaya et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
WRP/srGAP3 Facilitates the Initiation of Spine Development by an Inverse F-BAR Domain, and Its Loss Impairs Long-Term Memory
Benjamin R. Carlson et al.
JOURNAL OF NEUROSCIENCE (2011)
Mouse Model for Lowe Syndrome/Dent Disease 2 Renal Tubulopathy
Susan P. Bothwell et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2011)
Systematic resequencing of X-chromosome synaptic genes in autism spectrum disorder and schizophrenia
A. Piton et al.
MOLECULAR PSYCHIATRY (2011)
Functional PAK-2 knockout and replacement with a caspase cleavage-deficient mutant in mice reveals differential requirements of full-length PAK-2 and caspase-activated PAK-2p34
Jerry W. Marlin et al.
MAMMALIAN GENOME (2011)
Control of synapse development and plasticity by Rho GTPase regulatory proteins
Kimberley F. Tolias et al.
PROGRESS IN NEUROBIOLOGY (2011)
Delineation of Behavioral Phenotypes in Genetic Syndromes: Characteristics of Autism Spectrum Disorder, Affect and Hyperactivity
Chris Oliver et al.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS (2011)
Autistic and Psychiatric Findings Associated With the 3q29 Microdeletion Syndrome: Case Report and Review
Fabiola Quintero-Rivera et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART A (2010)
A Co-segregating Microduplication of Chromosome 15q11.2 Pinpoints Two Risk Genes for Autism Spectrum Disorder
Bert van der Zwaag et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2010)
Characterization of a Family with Rare Deletions in CNTNAP5 and DOCK4 Suggests Novel Risk Loci for Autism and Dyslexia
Alistair T. Pagnamenta et al.
BIOLOGICAL PSYCHIATRY (2010)
SFARI Gene: an evolving database for the autism research community
Sharmila Banerjee-Basu et al.
DISEASE MODELS & MECHANISMS (2010)
Trio Is a Key Guanine Nucleotide Exchange Factor Coordinating Regulation of the Migration and Morphogenesis of Granule Cells in the Developing Cerebellum
Ya-Jing Peng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Rac1 Regulates Neuronal Polarization through the WAVE Complex
Sabina Tahirovic et al.
JOURNAL OF NEUROSCIENCE (2010)
High-density SNP association study and copy number variation analysis of the AUTS1 and AUTS5 loci implicate the IMMP2L-DOCK4 gene region in autism susceptibility
E. Maestrini et al.
MOLECULAR PSYCHIATRY (2010)
Motorized RhoGAP myosin IXb (Myo9b) controls cell shape and motility
Peter J. Hanley et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Genome-wide linkage using the Social Responsiveness Scale in Utah autism pedigrees
Hilary Coon et al.
MOLECULAR AUTISM (2010)
Prevalence of autism-spectrum conditions: UK school-based population study
Simon Baron-Cohen et al.
BRITISH JOURNAL OF PSYCHIATRY (2009)
DOG 1.0: illustrator of protein domain structures
Jian Ren et al.
CELL RESEARCH (2009)
PAK signalling in neuronal physiology
Patricia Kreis et al.
CELLULAR SIGNALLING (2009)
Rac1 deficiency in the forebrain results in neural progenitor reduction and microcephaly
Lei Chen et al.
DEVELOPMENTAL BIOLOGY (2009)
A PH domain within OCRL bridges clathrin-mediated membrane trafficking to phosphoinositide metabolism
Yuxin Mao et al.
EMBO JOURNAL (2009)
Nine patients with a microdeletion 15q11.2 between breakpoints 1 and 2 of the Prader-Willi critical region, possibly associated with behavioural disturbances
Marianne Doornbos et al.
EUROPEAN JOURNAL OF MEDICAL GENETICS (2009)
Dynamic Expression of the Slit-Robo GTPase Activating Protein Genes during Development of the Murine Nervous System
Claire Bacon et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2009)
A central role for the small GTPase Rac1 in hippocampal plasticity and spatial learning and memory
Ursula Haditsch et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2009)
Increased network excitability and impaired induction of long-term potentiation in the dentate gyrus of collybistin-deficient mice in vivo
Peter Jedlicka et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2009)
A high-density SNP genome-wide linkage scan in a large autism extended pedigree
K. Allen-Brady et al.
MOLECULAR PSYCHIATRY (2009)
AutDB: a gene reference resource for autism research
Saumyendra N. Basu et al.
NUCLEIC ACIDS RESEARCH (2009)
Coordination of Rho and Rac GTPase Function via p190B RhoGAP
Rodrigo I. Bustos et al.
CURRENT BIOLOGY (2008)
Expression of MEGAP mRNA during embryonic development
Robert Waltereit et al.
GENE EXPRESSION PATTERNS (2008)
PX-RICS mediates ER-to-Golgi transport of the N-cadherin/β-catenin complex
Tsutomu Nakamura et al.
GENES & DEVELOPMENT (2008)
Mammalian Rho GTPases:: new insights into their functions from in vivo studies
Sarah J. Heasman et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Structural basis of protein kinase C isoform function
Susan F. Steinberg
PHYSIOLOGICAL REVIEWS (2008)
The atypical Rac activator Dock180 (Dock1) regulates myoblast fusion in vivo
Melanie Laurin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
P-Rex2 regulates Purkinje cell dendrite morphology and motor coordination
Sarah Donald et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Regulated shuttling of Slit-Robo-GTPase activating proteins between nucleus and cytoplasm during brain development
Qin Yao et al.
CELLULAR AND MOLECULAR NEUROBIOLOGY (2008)
Impaired GABAergic transmission and altered hippocampal synaptic plasticity in collybistin-deficient mice
Theofilos Papadopoulos et al.
EMBO JOURNAL (2007)
Crosstalk between the p 1 90-B RhoGAP and lGF signaling pathways is required for embryonic mammary bud development
Brandy M. Heckman et al.
DEVELOPMENTAL BIOLOGY (2007)
A role of the Lowe syndrome protein OCRL in early steps of the endocytic pathway
Kai S. Erdmann et al.
DEVELOPMENTAL CELL (2007)
Loss of X-linked mental retardation gene oligophrenin 1 in mice impairs spatial memory and leads to ventricular enlargement and dendritic spine immaturity
Malik Khelfaoui et al.
JOURNAL OF NEUROSCIENCE (2007)
PX-RICS, a novel splicing variant of RICS, is a main isoform expressed during neural development
Tomoatsu Hayashi et al.
GENES TO CELLS (2007)
Nap1-regulated neuronal cytoskeletal dynamics is essential for the final differentiation of neurons in cerebral cortex
Yukako Yokota et al.
NEURON (2007)
Rac1 controls the formation of midline commissures and the competency of tangential migration in ventral telencephalic neurons
Lei Chen et al.
JOURNAL OF NEUROSCIENCE (2007)
Current knowledge of the large RhoGAP family of proteins
Joseph Tcherkezian et al.
BIOLOGY OF THE CELL (2007)
Catching a GEF by its tail
Rafael Garcia-Mata et al.
TRENDS IN CELL BIOLOGY (2007)
GTP-binding proteins of the Rho/Rac family: regulation, effectors and functions in vivo
Xose R. Bustelo et al.
BIOESSAYS (2007)
Genetic targeting of principal neurons in neocortex and hippocampus of NEX-Cre mice
Sandra Goebbels et al.
GENESIS (2006)
Lack of association of MYO9B genetic variants with coeliac disease in a British cohort
K. A. Hunt et al.
GUT (2006)
Role of the Rho GTPase-activating protein RICS in neurite outgrowth
Yukiko Nasu-Nishimura et al.
GENES TO CELLS (2006)
Identification of novel neuronal isoforms of the Rho-GEF Trio
E Portales-Casamar et al.
BIOLOGY OF THE CELL (2006)
Distinct but overlapping functions for the closely related p190 RhoGAPs in neural development
Stephen F. Matheson et al.
DEVELOPMENTAL NEUROSCIENCE (2006)
Oligophrenin 1 mutations frequently cause X-linked mental retardation with cerebellar hypoplasia
G Zanni et al.
NEUROLOGY (2005)
3q29 Microdeletion syndrome: Clinical and molecular characterization of a new syndrome
L Willatt et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2005)
Generation and characterization of Rac3 knockout mice
S Corbetta et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Involvement of a Rac activator, P-Rex1, in neurotrophin-derived signaling and neuronal migration
M Yoshizawa et al.
JOURNAL OF NEUROSCIENCE (2005)
Multiple novel isoforms of Trio are expressed in the developing rat brain
CE McPherson et al.
GENE (2005)
GEF means go: Turning on Rho GTPases with guanine nucleotide-exchange factors
KL Rossman et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
The role of the Rho GTPases in neuronal development
EE Govek et al.
GENES & DEVELOPMENT (2005)
The X-linked mental retardation protein oligophrenin-1 is required for dendritic spine morphogenesis
EE Govek et al.
NATURE NEUROSCIENCE (2004)
Differential distribution of Rac1 and Rac3 GTPases in the developing mouse brain: implications for a role of Rac3 in Purkinje cell differentiation
A Bolis et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2003)
Slowed conduction and thin myelination of peripheral nerves associated with mutant Rho guanine-nucleotide exchange factor 10
K Verhoeven et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2003)
Lowe syndrome protein OCRL1 interacts with Rac GTPase in the trans-Golgi network
A Faucherre et al.
HUMAN MOLECULAR GENETICS (2003)
GC-GAP, a Rho family GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2
CM Zhao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The RhoGAP activity of OPHN1, a new F-actin-binding protein, is negatively controlled by its amino-terminal domain
F Fauchereau et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2003)
p250GAP, a novel brain-enriched GTPase-activating protein for Rho family GTPases, is involved in the N-methyl-D-aspartate receptor signaling
T Nakazawa et al.
MOLECULAR BIOLOGY OF THE CELL (2003)
RICS, a novel GTPase-activating protein for Cdc42 and Rac1, is involved in the β-catenin-N-cadherin and N-methyl-D-aspartate receptor signaling
T Okabe et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Loss of WAVE-1 causes sensorimotor retardation and reduced learning and memory in mice
SH Soderling et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Characterization of a brain-specific Rho GTPase-activating protein, p200RhoGAP
SY Moon et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Long-term potentiation and long-term depression in hippocampal CA1 neurons of mice lacking the IP3 type 1 receptor
T Nagase et al.
NEUROSCIENCE (2003)
Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity
JF Côté et al.
JOURNAL OF CELL SCIENCE (2002)
Grit, a GTPase-activating protein for the Rho family, regulates neurite extension through association with the TrkA receptor and N-Shc and CrkL/Crk adapter molecules
T Nakamura et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
The novel Rho-GTPase activating gene MEGAP/srGAP3 has a putative role in severe mental retardation
V Endris et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
p21-activated kinases: three more join the Pak
ZM Jaffer et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2002)
Characterization and expression analyses of the mouse Wiskott-Aldrich syndrome protein (WASP) family member Wave1/Scar
N Benachenhou et al.
GENE (2002)
Modulation of CREB activity by the Rho GTPase regulates cell and organism size during mouse embryonic development
R Sordella et al.
DEVELOPMENTAL CELL (2002)
P-Rex1, a PtdIns(3,4,5)P3- and Gβγ-regulated guanine-nucleotide exchange factor for Rac
HCE Welch et al.
CELL (2002)
Motor discoordination in mutant mice heterozygous for the type 1 inositol 1,4,5-trisphosphate receptor
H Ogura et al.
BEHAVIOURAL BRAIN RESEARCH (2001)
Distribution of transcripts for the brain-specific GDP/GTP exchange factor collybistin in the developing mouse brain
M Kneussel et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2001)
The Trio guanine nucleotide exchange factor is a RhoA target -: Binding of RhoA to the Trio immunoglobulin-like domain
QG Medley et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Skeletal muscle deformity and neuronal disorder in Trio exchange factor-deficient mouse embryos
SP O'Brien et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Synaptic plasticity in hippocampal CA1 neurons of mice lacking type 1 inositol-1,4,5-trisphosphate receptors
S Fujii et al.
LEARNING & MEMORY (2000)
Molecular cloning of a novel apoptosis-related gene, human Nap1 (NCKAP1), and its possible relation to Alzheimer disease
T Suzuki et al.
GENOMICS (2000)
Collybistin, a newly identified brain-specific GEF, induces submembrane clustering of gephyrin
S Kins et al.
NATURE NEUROSCIENCE (2000)