期刊
CELLS
卷 9, 期 3, 页码 -出版社
MDPI
DOI: 10.3390/cells9030696
关键词
homologous chromosomes; pairing; synaptonemal complex; cytoskeleton; LINC
类别
资金
- CNRS
- Inserm
- FRM [Equipe FRM DEQ20160334884]
- ANR [ANR-15-CE13-0001-01]
- College de France
- Bettencourt-Schueller foundations
- Agence Nationale de la Recherche (ANR) [ANR-15-CE13-0001] Funding Source: Agence Nationale de la Recherche (ANR)
Meiosis is a key event in the manufacturing of an oocyte. During this process, the oocyte creates a set of unique chromosomes by recombining paternal and maternal copies of homologous chromosomes, and by eliminating one set of chromosomes to become haploid. While meiosis is conserved among sexually reproducing eukaryotes, there is a bewildering diversity of strategies among species, and sometimes within sexes of the same species, to achieve proper segregation of chromosomes. Here, we review the very first steps of meiosis in females, when the maternal and paternal copies of each homologous chromosomes have to move, find each other and pair. We explore the similarities and differences observed in C. elegans, Drosophila, zebrafish and mouse females.
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