相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Molecular insights into kinase mediated signaling pathways of chemokines and their cognate G protein coupled receptors
Deepak Kumar Tripathi et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2020)
Adaptor Protein p66Shc: A Link Between Cytosolic and Mitochondrial Dysfunction in the Development of Diabetic Retinopathy
Manish Mishra et al.
ANTIOXIDANTS & REDOX SIGNALING (2019)
p66Shc deficiency in the Eμ-TCL1 mouse model of chronic lymphocytic leukemia enhances leukemogenesis by altering the chemokine receptor landscape
Laura Patrussi et al.
HAEMATOLOGICA (2019)
BCL-2 family isoforms in apoptosis and cancer
Chloe F. A. Warren et al.
CELL DEATH & DISEASE (2019)
P66shc and its role in ischemic cardiovascular diseases
Kerstin Boengler et al.
BASIC RESEARCH IN CARDIOLOGY (2019)
Chronic lymphocytic leukaemia: from genetics to treatment
Francesc Bosch et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2019)
Orchestration of Immunological Synapse Assembly by Vesicular Trafficking
Anna Onnis et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2019)
p66Shc deficiency sets the scene for clinically aggressive chronic lymphocytic leukemia
Richard Rosenquist
HAEMATOLOGICA (2019)
Overview of non-coding mutations in chronic lymphocytic leukemia
Valeria Spina et al.
MOLECULAR ONCOLOGY (2019)
p66Shc Contributes to Liver Fibrosis through the Regulation of Mitochondrial Reactive Oxygen Species
Yan Zhao et al.
THERANOSTICS (2019)
Abnormalities in chemokine receptor recycling in chronic lymphocytic leukemia
Laura Patrussi et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2019)
Oxidative Stress and Cancer: The Role of Nrf2
Soraya Sajadimajd et al.
CURRENT CANCER DRUG TARGETS (2018)
ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia-update on methodological approaches and results interpretation
J. Malcikova et al.
LEUKEMIA (2018)
Critical molecular pathways in CLL therapy
Gerardo Ferrer et al.
MOLECULAR MEDICINE (2018)
p66Shc deficiency enhances CXCR4 and CCR7 recycling in CLL B cells by facilitating their dephosphorylation-dependent release from β-arrestin at early endosomes
Laura Patrussi et al.
ONCOGENE (2018)
TCR Signaling: Mechanisms of Initiation and Propagation
Adam H. Courtney et al.
TRENDS IN BIOCHEMICAL SCIENCES (2018)
The pro-oxidant adaptor p66SHC promotes B cell mitophagy by disrupting mitochondrial integrity and recruiting LC3-II
Anna Onnis et al.
AUTOPHAGY (2018)
p66Shc activation promotes increased oxidative phosphorylation and renders CNS cells more vulnerable to amyloid beta toxicity
Asad Lone et al.
SCIENTIFIC REPORTS (2018)
Isotype Specific Assembly of B Cell Antigen Receptors and Synergism With Chemokine Receptor CXCR4
Palash C. Maity et al.
FRONTIERS IN IMMUNOLOGY (2018)
The Role of STAT Signaling Pathways in the Pathogenesis of Systemic Lupus Erythematosus
Ales Goropevsek et al.
CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY (2017)
CXCR4 signaling and function require the expression of the IgD-class B-cell antigen receptor
Martin Becker et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Differences between chronic lymphocytic leukaemia and small lymphocytic lymphoma cells by proteomic profiling and SNP microarray analysis
Jennifer A. Tooze et al.
CANCER GENETICS (2017)
Chronic lymphocytic leukemia: 2017 update on diagnosis, risk stratification, and treatment
Michael Hallek
AMERICAN JOURNAL OF HEMATOLOGY (2017)
Microenvironment interactions and B-cell receptor signaling in Chronic Lymphocytic Leukemia: Implications for disease pathogenesis and treatment
Elisa ten Hacken et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2016)
Gambogic Acid Inhibits Malignant Melanoma Cell Proliferation Through Mitochondrial p66shc/ROS-p53/Bax-Mediated Apoptosis
Lili Liang et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2016)
ROS and ROS-Mediated Cellular Signaling
Jixiang Zhang et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)
Role of interleukin-6 in cancer progression and therapeutic resistance
Neeraj Kumari et al.
TUMOR BIOLOGY (2016)
Expression of the p66Shc protein adaptor is regulated by the activator of transcription STAT4 in normal and chronic lymphocytic leukemia B cells
Francesca Cattaneo et al.
ONCOTARGET (2016)
Protein kinase D-dependent CXCR4 down-regulation upon BCR triggering is linked to lymphadenopathy in chronic lymphocytic leukaemia
Stephane Saint-Georges et al.
ONCOTARGET (2016)
Genomic and epigenomic heterogeneity in chronic lymphocytic leukemia
Romain Guieze et al.
BLOOD (2015)
Perturbation of the normal immune system in patients with CLL
Francesco Forconi et al.
BLOOD (2015)
Enhanced Chemokine Receptor Recycling and Impaired S1P1 Expression Promote Leukemic Cell Infiltration of Lymph Nodes in Chronic Lymphocytic Leukemia
Laura Patrussi et al.
CANCER RESEARCH (2015)
Chemokines, their receptors and human disease: the good, the bad and the itchy
Vanessa L. Bryant et al.
IMMUNOLOGY AND CELL BIOLOGY (2015)
Redox regulation of FoxO transcription factors
Lars-Oliver Klotz et al.
REDOX BIOLOGY (2015)
Role of miR-15/16 in CLL
Y. Pekarsky et al.
CELL DEATH AND DIFFERENTIATION (2015)
Mitochondrial metabolism contributes to oxidative stress and reveals therapeutic targets in chronic lymphocytic leukemia
Regina Jitschin et al.
BLOOD (2014)
Prolonged lymphocytosis during ibrutinib therapy is associated with distinct molecular characteristics and does not indicate a suboptimal response to therapy
Jennifer A. Woyach et al.
BLOOD (2014)
Endocytic trafficking of chemokine receptors
Adriano Marchese
CURRENT OPINION IN CELL BIOLOGY (2014)
β-arrestin-1 mediates the TCR-triggered re-routing of distal receptors to the immunological synapse by a PKC-mediated mechanism
Elena Fernandez-Arenas et al.
EMBO JOURNAL (2014)
p66Shc regulates vesicle-mediated secretion in mast cells by affecting F-actin dynamics
Giulia Masi et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2014)
The Adaptor Protein p66Shc Inhibits mTOR-Dependent Anabolic Metabolism
Mohamed A. Soliman et al.
SCIENCE SIGNALING (2014)
The microenvironment in chronic lymphocytic leukemia (CLL) and other B cell malignancies: Insight into disease biology and new targeted therapies
Jan A. Burger et al.
SEMINARS IN CANCER BIOLOGY (2014)
The Meaning and Relevance of B-Cell Receptor Structure and Function in Chronic Lymphocytic Leukemia
Freda K. Stevenson et al.
SEMINARS IN HEMATOLOGY (2014)
Negative regulation of chemokine receptor signaling and B-cell chemotaxis by p66Shc
L. Patrussi et al.
CELL DEATH & DISEASE (2014)
The Pathogenesis of Chronic Lymphocytic Leukemia
Suping Zhang et al.
Annual Review of Pathology-Mechanisms of Disease (2013)
ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets
Andrew J. Souers et al.
NATURE MEDICINE (2013)
Modulation of oxidative stress as an anticancer strategy
Chiara Gorrini et al.
NATURE REVIEWS DRUG DISCOVERY (2013)
B cell receptor signaling in chronic lymphocytic leukemia
Jan A. Burger et al.
TRENDS IN IMMUNOLOGY (2013)
p66Shc-dependent apoptosis requires Lck and CamKII activity
Laura Patrussi et al.
APOPTOSIS (2012)
S1P1 expression is controlled by the pro-oxidant activity of p66Shc and is impaired in B-CLL patients with unfavorable prognosis
Nagaja Capitani et al.
BLOOD (2012)
Novel Insights in Molecular Mechanisms of CLL
Nicola Zanesi et al.
CURRENT PHARMACEUTICAL DESIGN (2012)
Recruitment mechanisms of primary and malignant B cells to the human liver
Shishir Shetty et al.
HEPATOLOGY (2012)
CD38 and chronic lymphocytic leukemia: a decade later
Fabio Malavasi et al.
BLOOD (2011)
p66Shc Is a Negative Regulator of FcεRI-Dependent Signaling in Mast Cells
Cristina Ulivieri et al.
JOURNAL OF IMMUNOLOGY (2011)
Nurture versus Nature: The Microenvironment in Chronic Lymphocytic Leukemia
Jan A. Burger
HEMATOLOGY-AMERICAN SOCIETY OF HEMATOLOGY EDUCATION PROGRAM (2011)
Impaired expression of p66Shc, a novel regulator of B-cell survival, in chronic lymphocytic leukemia
Nagaja Capitani et al.
BLOOD (2010)
Down-regulation of CXCR4 and CD62L in Chronic Lymphocytic Leukemia Cells Is Triggered by B-Cell Receptor Ligation and Associated with Progressive Disease
Amalia Vlad et al.
CANCER RESEARCH (2009)
Positive and negative regulation of antigen receptor signaling by the Shc family of protein adapters
Francesca Finetti et al.
IMMUNOLOGICAL REVIEWS (2009)
Epigenetic changes during disease progression in a murine model of human chronic lymphocytic leukemia
Shih-Shih Chen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Final common molecular pathways of aging and cardiovascular disease - Role of the p66(Shc) protein
Francesco Cosentino et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2008)
The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells
Pablo G. Longo et al.
BLOOD (2008)
The proapoptotic and antimitogenic protein p66SHC acts as a negative regulator of lymphocyte activation and autoimmunity
Francesca Finetti et al.
BLOOD (2008)
Pharmacological PKA Inhibition: All May Not Be What It Seems
Andrew J. Murray
SCIENCE SIGNALING (2008)
Overexpression of the CXCR5 chemokine receptor, and its ligand, CXCL13 in B-cell chronic lymphocytic leukemia
Andrea Buerkle et al.
BLOOD (2007)
P52Shc is required for CXCR4-dependent signaling and chemotaxis in T cells
Laura Patrussi et al.
BLOOD (2007)
The prognostic role of CXCR3 expression by chronic lymphocytic leukemia B cells
Esther Ocana et al.
HAEMATOLOGICA (2007)
Protein kinase C β and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66Shc
Paolo Pinton et al.
SCIENCE (2007)
p66SHC promotes T cell apoptosis by inducing mitochondrial dysfunction and impaired Ca2+ homeostasis
M. Pellegrini et al.
CELL DEATH AND DIFFERENTIATION (2007)
Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737
Victoria Del Gaizo Moore et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Expression in T-cells of the proapoptotic protein p66SHC is controlled by promoter demethylation
Alfredo Pezzicoli et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
CXCR4 physically associates with the T cell receptor to signal in T cells
Ashok Kumar et al.
IMMUNITY (2006)
Clinical implications of ZAP-70 expression in chronic lymphocytic leukemia
Francesc Bosch et al.
CYTOMETRY PART B-CLINICAL CYTOMETRY (2006)
ZAP-70 expression is associated with enhanced ability to respond to migratory and survival signals in B-cell chronic lymphocytic leukemia (B-CLL)
SJ Richardson et al.
BLOOD (2006)
Apoptosis and aging:: Role of p66Shc Redox protein
Enrica Migliaccio et al.
ANTIOXIDANTS & REDOX SIGNALING (2006)
miR-15 and miR-16 induce apoptosis by targeting BCL2
A Cimmino et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis
M Giorgio et al.
CELL (2005)
Bodyguards and assassins: Bcl-2 family proteins and apoptosis control in chronic lymphocytic leukaemia
G Packham et al.
IMMUNOLOGY (2005)
p66SHC promotes apoptosis and antagonizes mitogenic signaling in T cells
S Pacini et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1
M Matloubian et al.
NATURE (2004)
Chemokine receptors that mediate B cell homing to secondary lymphoid tissues are highly expressed in B cell chronic lymphocytic leukemia and non-Hodgkin lymphomas with widespread nodular dissemination
S López-Giral et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2004)
Homeostatic chemokines drive migration of malignant B cells in patients with non-Hodgkin lymphomas
L Trentin et al.
BLOOD (2004)
The life span determinant p66Shc localizes to mitochondria where it associates with mitochondrial heat shock protein 70 and regulates trans-membrane potential
F Orsini et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
GA Calin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
The p66Shc longevity gene is silenced through epigenetic modifications of an alternative promoter
A Ventura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
B-cell chronic lymphocytic leukemia cells express a surface membrane phenotype of activated, antigen-experienced B lymphocytes
RN Damle et al.
BLOOD (2002)
Human chronic lymphocytic leukemia modeled in mouse by targeted TCL1 expression
R Bichi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Downstream of kinase, p62dok, is a mediator of FcγRIIB inhibition of FcεRI signaling
VL Ott et al.
JOURNAL OF IMMUNOLOGY (2002)
The chemokine receptor CCR7 and α4 integrin are important for migration of chronic lymphocytic leukemia cells into lymph nodes
KJ Till et al.
BLOOD (2002)
Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway
S Nemoto et al.
SCIENCE (2002)
Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells
U Klein et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2001)
Effects of Src homology domain 2 (SH2)-containing inositol phosphatase (SHIP), SH2-containing phosphotyrosine phosphatase (SHP)-1, and SHP-2SH2 decoy proteins on FcγRIIB1-effector interactions and inhibitory functions
K Nakamura et al.
JOURNAL OF IMMUNOLOGY (2000)