4.6 Article

First Report of OXA-181-Producing Klebsiella pneumoniae in China

期刊

INFECTION AND DRUG RESISTANCE
卷 13, 期 -, 页码 995-998

出版社

DOVE MEDICAL PRESS LTD
DOI: 10.2147/IDR.S237793

关键词

OXA-181; Klebsiella pneumoniae; IncX3 plasmid; China; human

资金

  1. National Natural Science Foundation of China [81772250, 81861138052, 31761133004]

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We present here the first report of an OXA-181-producing Klebsiella pneumoniae isolated from the fecal specimen of a patient in China. The OXA-181-encoding gene bla(OXA-181) was located on a 51 kb IncX3-type plasmid. Conjugation assay and whole-genome sequencing analysis revealed that this transferrable plasmid in the K. pneumoniae isolate might have originated from Escherichia coli and have the potential to mediate the spread of bla(OXA-181).

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