4.8 Editorial Material

Why does caloric restriction increase life and healthspan? The 'clean cupboards' hypothesis

期刊

NATIONAL SCIENCE REVIEW
卷 7, 期 7, 页码 1153-1156

出版社

OXFORD UNIV PRESS
DOI: 10.1093/nsr/nwaa078

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资金

  1. National Natural Science Foundation of China [91731303, 91649108]
  2. Royal Society (Wolfson Merit Award)
  3. Biotechnology and Biological Sciences Research Council of the UK [BB/P009875/1]
  4. KC Wong Education Foundation
  5. Chinese Academy of Sciences [XDB 13030100]
  6. BBSRC [BB/P009875/1] Funding Source: UKRI

向作者/读者索取更多资源

The disposable soma hypothesis explanation of the effects of caloric restriction (CR) on lifespan fails to explain why CR generates negative impacts alongside the positive effects and does not work in all species. I propose here a novel idea called the clean cupboards hypothesis which overcomes these problems.

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