4.6 Article

The Location of the Pseudoautosomal Boundary in Silene latifolia

期刊

GENES
卷 11, 期 6, 页码 -

出版社

MDPI
DOI: 10.3390/genes11060610

关键词

sex chromosome; Silene latifolia; pseudoautosomal region; recombination

资金

  1. BBSRC [BB/P009808/1]
  2. BBSRC [BB/P009808/1] Funding Source: UKRI

向作者/读者索取更多资源

Y-chromosomes contain a non-recombining region (NRY), and in many organisms it was shown that the NRY expanded over time. How and why the NRY expands remains unclear. Young sex chromosomes, where NRY expansion occurred recently or is on-going, offer an opportunity to study the causes of this process. Here, we used the plantSilene latifolia, where sex chromosomes evolved similar to 11 million years ago, to study the location of the boundary between the NRY and the recombining pseudoautosomal region (PAR). The previous work devoted to the NRY/PAR boundary inS. latifoliawas based on a handful of genes with locations approximately known from the genetic map. Here, we report the analysis of 86 pseudoautosomal and sex-linked genes adjacent to theS. latifoliaNRY/PAR boundary to establish the location of the boundary more precisely. We take advantage of the dense genetic map and polymorphism data from wild populations to identify 20 partially sex-linked genes located in the fuzzy boundary, that rarely recombines in male meiosis. Genes proximal to this fuzzy boundary show no evidence of recombination in males, while the genes distal to this partially-sex-linked region are actively recombining in males. Our results provide a more accurate location for the PAR boundary inS. latifolia, which will help to elucidate the causes of PAR boundary shifts leading to NRY expansion over time.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.6
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

暂无数据
暂无数据