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Resistance and gain-of-resistance phenotypes in cancers harboring wild-type p53
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BRCA1/2 mutations and expression: Response to platinum chemotherapy in patients with advanced stage epithelial ovarian cancer
Rebecca Byler Dann et al.
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Replacement of cisplatin with nedaplatin in a definitive 5-fluorouracil/cisplatin-based chemoradiotherapy in Japanese patients with esophageal squamous cell carcinoma
Akiko Kuwahara et al.
International Journal of Medical Sciences (2012)
The CXXC motifs in the metal binding domains are required for ATP7B to mediate resistance to cisplatin
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MOLECULAR CANCER THERAPEUTICS (2012)
Role of multidrug resistance protein 2 (MRP2) in chemoresistance and clinical outcome in oesophageal squamous cell carcinoma
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BRITISH JOURNAL OF CANCER (2011)
Role of Endonucleases XPF and XPG in Nucleotide Excision Repair of Platinated DNA and Cisplatin/Oxaliplatin Cytotoxicity
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Secondary Somatic Mutations Restoring BRCA1/2 Predict Chemotherapy Resistance in Hereditary Ovarian Carcinomas
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JOURNAL OF CLINICAL ONCOLOGY (2011)
Copper Transporter 2 Regulates Endocytosis and Controls Tumor Growth and Sensitivity to Cisplatin In Vivo
Brian G. Blair et al.
MOLECULAR PHARMACOLOGY (2011)
The Mutational Landscape of Head and Neck Squamous Cell Carcinoma
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SCIENCE (2011)
Targeting the prodeath and prosurvival functions of autophagy as novel therapeutic strategies in cancer
Kevin N. Dalby et al.
AUTOPHAGY (2010)
Increased levels and defective glycosylation of MRPs in ovarian carcinoma cells resistant to oxaliplatin
Giovanni Luca Beretta et al.
BIOCHEMICAL PHARMACOLOGY (2010)
Differential transport of platinum compounds by the human organic cation transporter hOCT2 (hSLC22A2)
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Silencing MRP4 by small interfering RNA reverses acquired DDP resistance of gastric cancer cell
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CANCER LETTERS (2010)
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CRITICAL REVIEWS IN TOXICOLOGY (2010)
The status of platinum anticancer drugs in the clinic and in clinical trials
Nial J. Wheate et al.
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Downregulation of XPF-ERCC1 enhances cisplatin efficacy in cancer cells
Sanjeevani Arora et al.
DNA REPAIR (2010)
An Adsorptive Transfer Technique Coupled with Brdicka Reaction to Reveal the Importance of Metallothionein in Chemotherapy with Platinum Based Cytostatics
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INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2010)
Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary
Ashour Ahmed Ahmed et al.
JOURNAL OF PATHOLOGY (2010)
Copper Transporters and the Cellular Pharmacology of the Platinum-Containing Cancer Drugs
Stephen B. Howell et al.
MOLECULAR PHARMACOLOGY (2010)
Hypoxia-Inducible Factor 1α Determines Gastric Cancer Chemosensitivity via Modulation of p53 and NF-κB
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PLOS ONE (2010)
Cisplatin Interaction with Amino Acids Cysteine and Methionine from Gas Phase to Solutions with Constant pH
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INTERDISCIPLINARY SCIENCES-COMPUTATIONAL LIFE SCIENCES (2010)
Hypoxia-inducible factor-1 alpha, in association with inflammation, angiogenesis and MYC, is a critical prognostic factor in patients with HCC after surgery
Chen-Xin Dai et al.
BMC CANCER (2009)
Modes of p53 Regulation
Jan-Philipp Kruse et al.
CELL (2009)
Copper Transporter 2 Regulates the Cellular Accumulation and Cytotoxicity of Cisplatin and Carboplatin
Brian G. Blair et al.
CLINICAL CANCER RESEARCH (2009)
Human copper transporters: mechanism, role in human diseases and therapeutic potential
Arnab Gupta et al.
FUTURE MEDICINAL CHEMISTRY (2009)
Increased levels of copper efflux transporter ATP7B are associated with poor outcome in colorectal cancer patients receiving oxaliplatin-based chemotherapy
Eva Martinez-Balibrea et al.
INTERNATIONAL JOURNAL OF CANCER (2009)
Crystal Structures of Cisplatin Bound to a Human Copper Chaperone
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JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
The ERCC1/XPF endonuclease is required for completion of homologous recombination at DNA replication forks stalled by inter-strand cross-links
Ali Z. Al-Minawi et al.
NUCLEIC ACIDS RESEARCH (2009)
Prognostic significance of hypoxia-inducible factor-1α, TWIST1 and Snail expression in resectable non-small cell lung cancer
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THORAX (2009)
The role of cellular accumulation in determining sensitivity to platinum-based chemotherapy
Matthew D. Hall et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY (2008)
Altered localisation of the copper efflux transporters ATP7A and ATP7B associated with cisplatin resistance in human ovarian carcinoma cells
Ganna V. Kalayda et al.
BMC CANCER (2008)
Oxidative stress is inherent in prostate cancer cells and is required for aggressive phenotype
Binod Kumar et al.
CANCER RESEARCH (2008)
Transcriptional control of human p53-regulated genes
Todd Riley et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2008)
Transport of cisplatin by the copper efflux transporter ATP7B
Roohangiz Safaei et al.
MOLECULAR PHARMACOLOGY (2008)
HYPOXIA AND METABOLISM SERIES - TIMELINE The impact of O2 availability on human cancer
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NATURE REVIEWS CANCER (2008)
Enhanced repair of DNA interstrand crosslinking in ovarian cancer cells from patients following treatment with platinum-based chemotherapy
P. Wynne et al.
BRITISH JOURNAL OF CANCER (2007)
Human copper transporter 2 is localized in late endosomes and lysosomes and facilitates cellular copper uptake
Peter V. E. Van den Berghe et al.
BIOCHEMICAL JOURNAL (2007)
Expression of hypoxia-inducible factor 1α, hypoxia-inducible factor 2α, and von Hippel-Lindau protein in epitheLiaL ovarian neoplasms and allelic loss of von Hippel-Lindau gene:: nuclear expression of hypoxia-inducible factor 1α is an independent prognostic factor in ovarian carcinoma
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HUMAN PATHOLOGY (2007)
Differential contribution of organic cation transporters, OCT2 and MATE1, in platinum agent-induced nephrotoxicity
Sachiko Yokoo et al.
BIOCHEMICAL PHARMACOLOGY (2007)
The role of ubiquitination in the direct mitochondrial death program of p53
Natasha D. Marchenko et al.
CELL CYCLE (2007)
Tumor microenvironment: The role of the tumor stroma in cancer
Hanchen Li et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2007)
Direct cellular responses to platinum-induced DNA damage
Yongwon Jung et al.
CHEMICAL REVIEWS (2007)
Mitochondria and reactive oxygen species in renal cancer
Eric Hervouet et al.
BIOCHIMIE (2007)
ABCC2 (MRP2, cMOAT) can be localized in the nuclear membrane of ovarian carcinomas and correlates with resistance to cisplatin and clinical outcome
Pawel Surowiak et al.
CLINICAL CANCER RESEARCH (2006)
The internalization and degradation of human copper transporter 1 following cisplatin exposure
Alison K. Holzer et al.
CANCER RESEARCH (2006)
Cisplatin and oxaliplatin, but not carboplatin and nedaplatin, are substrates for human organic cation transporters (SLC22A1-3 and multidrug and toxin extrusion family)
Atsushi Yonezawa et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
Contribution of the major copper influx transporter CTR1 to the cellular accumulation of cisplatin, carboplatin, and oxaliplatin
Alison K. Holzer et al.
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Molecular mechanisms of mammalian global genome nucleotide excision repair
LCJ Gillet et al.
CHEMICAL REVIEWS (2006)
Platinum anticancer drug damage enforces a particular rotational setting of DNA in nucleosomes
AJ Danford et al.
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Augmentation of cisplatin sensitivity in cisplatin-resistant human bladder cancer cells by modulating glutathione concentrations and glutathione-related enzyme activities
SS Byun et al.
BJU INTERNATIONAL (2005)
Recognition and processing of cisplatin- and oxaliplatin-DNA adducts
SG Chaney et al.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2005)
In vivo activation of the p53 pathway by small-molecule antagonists of MDM2
LT Vassilev et al.
SCIENCE (2004)
Modulation of the cellular pharmacology of cisplatin and its analogs by the copper exporters ATP7A and ATP7B
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MOLECULAR PHARMACOLOGY (2004)
Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors
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NATURE MEDICINE (2004)
DNA strand breaks and apoptosis induced by oxaliplatin in cancer cells
S Faivre et al.
BIOCHEMICAL PHARMACOLOGY (2003)
Current status of the molecular mechanisms of anticancer drug-induced apoptosis - The contribution of molecular-level analysis to cancer chemotherapy
R Kim et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2002)
Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals
S Ishida et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Recognition of cisplatin adducts by cellular proteins
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Oxaliplatin-induced damage of cellular DNA
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A family of drug transporters: The multidrug resistance-associated proteins
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JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2000)