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Alicia R. Martin et al.
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Lena-Marie Grunwald et al.
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Bilal Cakir et al.
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Generation of complex human organoid models including vascular networks by incorporation of mesodermal progenitor cells
Philipp Woersdoerfer et al.
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Michael Lombardo et al.
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Simon T. Schafer et al.
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Mathieu Quesnel-Vallieres et al.
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Eyal Karzbrun et al.
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Fabiele Baldino Russo et al.
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Sandra M. Sanchez-Sanchez et al.
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Joseph Park et al.
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Yuan-Ta Lin et al.
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Anna Sahakyan et al.
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Convergent Pathways in Idiopathic Autism Revealed by Time Course Transcriptomic Analysis of Patient-Derived Neurons
Brooke A. DeRosa et al.
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Ralda Nehme et al.
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Bruno Di Stefano et al.
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The fragile X mutation impairs homeostatic plasticity in human neurons by blocking synaptic retinoic acid signaling
Zhenjie Zhang et al.
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AMERICAN JOURNAL OF HUMAN GENETICS (2018)
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Frank Soldner et al.
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Lost in Translation: Traversing the Complex Path from Genomics to Therapeutics in Autism Spectrum Disorder
Nenad Sestan et al.
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Spatiotemporal transcriptomic divergence across human and macaque brain development
Ying Zhu et al.
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Anahita Amiri et al.
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Xiaozhuo Liu et al.
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M. C. Marchetto et al.
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Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects
Christian R. Marshall et al.
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The human-induced pluripotent stem cell initiative-data resources for cellular genetics
Ian Streeter et al.
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Helena Kilpinen et al.
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Giorgia Quadrato et al.
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Florian T. Merkle et al.
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Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders
Daniel J. Weiner et al.
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Nan Yang et al.
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Whole genome sequencing in psychiatric disorders: the WGSPD consortium
Stephan J. Sanders et al.
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Jacob A. S. Vorstman et al.
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Michael Morrison et al.
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Ping Wang et al.
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hPSCreg-the human pluripotent stem cell registry
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Complexities of X chromosome inactivation status in female human induced pluripotent stem cells-a brief review and scientific update for autism research
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Andreas Leha et al.
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Analysis of protein-coding genetic variation in 60,706 humans
Monkol Lek et al.
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Parent-of-origin-specific signatures of de novo mutations
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Pleiotropic Mechanisms Indicated for Sex Differences in Autism
Ileena Mitra et al.
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Jessica Mariani et al.
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An integrated map of structural variation in 2,504 human genomes
Peter H. Sudmant et al.
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Stephan J. Sanders et al.
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22q11.2 deletion syndrome
Donna M. McDonald-McGinn et al.
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Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons
K. Griesi-Oliveira et al.
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Markus Kaufmann et al.
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Ivan Iossifov et al.
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Biological insights from 108 schizophrenia-associated genetic loci
Stephan Ripke et al.
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iPSC-Derived Forebrain Neurons from FXS Individuals Show Defects in Initial Neurite Outgrowth
Matthew E. Doers et al.
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Florian T. Merkle et al.
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Yingsha Zhang et al.
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Epigenetic Characterization of the FMR1 Gene and Aberrant Neurodevelopment in Human Induced Pluripotent Stem Cell Models of Fragile X Syndrome
Steven D. Sheridan et al.
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Gabsang Lee et al.
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John T. Dimos et al.
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Kazutoshi Takahashi et al.
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