期刊
CHEMOSPHERE
卷 150, 期 -, 页码 528-535出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.chemosphere.2015.10.087
关键词
Organophosphorus flame retardants; Phthalate esters; Indoor dust; Bioaccessibility; Risk assessment
资金
- National Natural Science Foundation of China [21307055]
- Jiangsu Provincial Natural Science Foundation of China [BK20130558]
Incidental ingestion of indoor dust is an important pathway for human exposure to organophosphorus flame retardants (OPFRs) and phthalate esters (PAEs). However, little is known about their bioaccessibility in indoor dust. In this study, indoor dust samples were collected from houses, offices, public microenvironments (PMEs), and university dorms, and physiologically based extraction test (PBET) was used to measure the bioaccessibility of OPFRs and PAEs in these dust samples. Total concentrations of OPFR5 in dust samples ranged from 0.01 to 63.2 mu g g(-1), with significantly lower concentrations in dorm dust (median = 0.30 mu g g(-1)) than those in houses (3.12), offices (5.94), and PMEs (11.6). Total PAEs ranged from 5.49 to 2161 mu g g(-1) with significantly lower concentrations in dorm dust (379 mu g g(-1)) than those in the other three types of dust (767, 515, and 731 mu g g(-1)). When subject to PBET, the bioaccessibility of OPFR5 ranged from 8.18% (triphenyl phosphate) to 54.5% (Tris(2-chloroisopropyl) phosphate) for OPFRs, and from 1.21% (di-2-ethylhexyl phthalate, DEHP) to 81.1% (dimethyl phthalate) for PAEs. Estimated exposure doses for adults and infants to OPFRs via dust ingestion were much lower than the reference doses (RfD), but intake dose of DEHP for infants was higher than the RfD of 20 mu g kg(-1) d(-1). However, the DEHP intake dose did not exceed the RfD after incorporating bioaccessibility into risk assessment. Our data indicated the importance of considering contaminant bioaccessibility during risk assessment of indoor dust. (C) 2015 Elsevier Ltd. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据