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A Real Time PCR Platform for the Simultaneous Quantification of Total and Extrachromosomal HIV DNA Forms in Blood of HIV-1 Infected Patients
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PLOS ONE (2014)
CCR5 Gene Disruption via Lentiviral Vectors Expressing Cas9 and Single Guided RNA Renders Cells Resistant to HIV-1 Infection
Weiming Wang et al.
PLOS ONE (2014)
Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues
Courtney V. Fletcher et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Quantification of HIV-1 latency reversal in resting CD4+ T cells from patients on suppressive antiretroviral therapy
Anthony R. Cillo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection
Wenhui Hu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Proliferation of cells with HIV integrated into cancer genes contributes to persistent infection
Thor A. Wagner et al.
SCIENCE (2014)
Specific HIV integration sites are linked to clonal expansion and persistence of infected cells
F. Maldarelli et al.
SCIENCE (2014)
The transient HIV remission in the Mississippi baby: why is this good news?
Jintanat Ananworanich et al.
JOURNAL OF THE INTERNATIONAL AIDS SOCIETY (2014)
Histone Deacetylase Inhibitors Impair the Elimination of HIV-Infected Cells by Cytotoxic T-Lymphocytes
Richard Brad Jones et al.
PLOS PATHOGENS (2014)
HIV-1 DNA predicts disease progression and post-treatment virological control.
James P. Williams et al.
ELIFE (2014)
Disulfiram reactivates latent HIV-1 expression through depletion of the phosphatase and tensin homolog
Genevieve Doyon et al.
AIDS (2013)
Stochastic Fate Selection in HIV-Infected Patients
Ariel D. Weinberger et al.
CELL (2013)
Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure
Ya-Chi Ho et al.
CELL (2013)
Increase in 2-Long Terminal Repeat Circles and Decrease in D-dimer After Raltegravir Intensification in Patients With Treated HIV Infection: A Randomized, Placebo-Controlled Trial
Hiroyu Hatano et al.
JOURNAL OF INFECTIOUS DISEASES (2013)
Quantitation of HIV-1 DNA with a sensitive TaqMan assay that has broad subtype specificity
Renee M. van der Sluis et al.
JOURNAL OF VIROLOGICAL METHODS (2013)
Quantitation of HIV DNA integration: Effects of differential integration site distributions on Alu-PCR assays
Troy Brady et al.
JOURNAL OF VIROLOGICAL METHODS (2013)
An Increasing Proportion of Monotypic HIV-1 DNA Sequences during Antiretroviral Treatment Suggests Proliferation of HIV-Infected Cells
Thor A. Wagner et al.
JOURNAL OF VIROLOGY (2013)
A Novel PCR Assay for Quantification of HIV-1 RNA
Liang Shan et al.
JOURNAL OF VIROLOGY (2013)
Preferential HIV Infection of CCR6+ Th17 Cells Is Associated with Higher Levels of Virus Receptor Expression and Lack of CCR5 Ligands
Yelina Alvarez et al.
JOURNAL OF VIROLOGY (2013)
Absence of Detectable HIV-1 Viremia after Treatment Cessation in an Infant
Deborah Persaud et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Highly Precise Measurement of HIV DNA by Droplet Digital PCR
Matthew C. Strain et al.
PLOS ONE (2013)
Gag-Positive Reservoir Cells Are Susceptible to HIV-Specific Cytotoxic T Lymphocyte Mediated Clearance
Erin H. Graf et al.
PLOS ONE (2013)
The HIV-1 reservoir in eight patients on long-term suppressive antiretroviral therapy is stable with few genetic changes over time
Lina Josefsson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Quantitative analysis of the time-course of viral DNA forms during the HIV-1 life cycle
Soundasse Munir et al.
RETROVIROLOGY (2013)
Reactivation of latent HIV-1 in central memory CD4+ T cells through TLR-1/2 stimulation
Camille L. Novis et al.
RETROVIROLOGY (2013)
Anti-HIV designer T cells progressively eradicate a latently infected cell line by sequentially inducing HIV reactivation then killing the newly gp120-positive cells
Gautam K. Sahu et al.
VIROLOGY (2013)
Harnessing the CRISPR/Cas9 system to disrupt latent HIV-1 provirus
Hirotaka Ebina et al.
SCIENTIFIC REPORTS (2013)
Comparative Analysis of Measures of Viral Reservoirs in HIV-1 Eradication Studies
Susanne Eriksson et al.
PLOS PATHOGENS (2013)
Rapid Quantification of the Latent Reservoir for HIV-1 Using a Viral Outgrowth Assay
Gregory M. Laird et al.
PLOS PATHOGENS (2013)
Concurrent measures of total and integrated HIV DNA monitor reservoirs and ongoing replication in eradication trials
Angela M. Mexas et al.
AIDS (2012)
Redefining the Viral Reservoirs that Prevent HIV-1 Eradication
Evelyn Eisele et al.
IMMUNITY (2012)
Stimulation of HIV-1-Specific Cytolytic T Lymphocytes Facilitates Elimination of Latent Viral Reservoir after Virus Reactivation
Liang Shan et al.
IMMUNITY (2012)
No Effect of Raltegravir Intensification on Viral Replication Markers in the Blood of HIV-1-Infected Patients Receiving Antiretroviral Therapy
Rajesh T. Gandhi et al.
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES (2012)
Modest Nonadherence to Antiretroviral Therapy Promotes Residual HIV-1 Replication in the Absence of Virological Rebound in Plasma
Alexander O. Pasternak et al.
JOURNAL OF INFECTIOUS DISEASES (2012)
Low-level detection and quantitation of cellular HIV-1 DNA and 2-LTR circles using droplet digital PCR
Timothy J. Henrich et al.
JOURNAL OF VIROLOGICAL METHODS (2012)
Administration of vorinostat disrupts HIV-1 latency in patients on antiretroviral therapy
N. M. Archin et al.
NATURE (2012)
SAMHD1 restricts HIV-1 infection in resting CD4+ T cells
Hanna-Mari Baldauf et al.
NATURE MEDICINE (2012)
A Flexible Model of HIV-1 Latency Permitting Evaluation of Many Primary CD4 T-Cell Reservoirs
Kara G. Lassen et al.
PLOS ONE (2012)
High-Throughput Droplet Digital PCR System for Absolute Quantitation of DNA Copy Number
Benjamin J. Hindson et al.
ANALYTICAL CHEMISTRY (2011)
A Therapeutic Dendritic Cell-Based Vaccine for HIV-1 Infection
Felipe Garcia et al.
JOURNAL OF INFECTIOUS DISEASES (2011)
Altered dynamics and differential infection profiles of lymphoid and myeloid cell subsets during acute and chronic HIV-1 infection
Mireille Centlivre et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2011)
Disulfiram Reactivates Latent HIV-1 in a Bcl-2-Transduced Primary CD4+ T Cell Model without Inducing Global T Cell Activation
Sifei Xing et al.
JOURNAL OF VIROLOGY (2011)
Clonal Sequences Recovered from Plasma from Patients with Residual HIV-1 Viremia and on Intensified Antiretroviral Therapy Are Identical to Replicating Viral RNAs Recovered from Circulating Resting CD4+ T Cells
Jeffrey A. Anderson et al.
JOURNAL OF VIROLOGY (2011)
The role of unintegrated DNA in HIV infection
Richard D. Sloan et al.
RETROVIROLOGY (2011)
HIV Latency
Robert F. Siliciano et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2011)
Short-Course Raltegravir Intensification Does Not Reduce Persistent Low-Level Viremia in Patients with HIV-1 Suppression during Receipt of Combination Antiretroviral Therapy
D. McMahon et al.
CLINICAL INFECTIOUS DISEASES (2010)
Bryostatin-1 Synergizes with Histone Deacetylase Inhibitors to Reactivate HIV-1 from Latency
Moises Perez et al.
CURRENT HIV RESEARCH (2010)
AIDS Clinical Trials Group 5197: A Placebo-Controlled Trial of Immunization of HIV-1-Infected Persons with a Replication-Deficient Adenovirus Type 5 Vaccine Expressing the HIV-1 Core Protein
Robert T. Schooley et al.
JOURNAL OF INFECTIOUS DISEASES (2010)
Differences in HIV Burden and Immune Activation within the Gut of HIV-Positive Patients Receiving Suppressive Antiretroviral Therapy
Steven A. Yukl et al.
JOURNAL OF INFECTIOUS DISEASES (2010)
Novel application of Locked Nucleic Acid chemistry for a Taqman assay for measuring diverse human immunodeficiency virus type 1 subtypes
Peilin Li et al.
JOURNAL OF VIROLOGICAL METHODS (2010)
HIV-1 replication and immune dynamics are affected by raltegravir intensification of HAART-suppressed subjects
Maria J. Buzon et al.
NATURE MEDICINE (2010)
Profound Depletion of HIV-1 Transcription in Patients Initiating Antiretroviral Therapy during Acute Infection
Adrian Schmid et al.
PLOS ONE (2010)
Noninvasive in vivo imaging of CD4 cells in simian-human immunodeficiency virus (SHIV)-infected nonhuman primates
Michele Di Mascio et al.
BLOOD (2009)
Development and Assessment of a Multiplex Real-Time PCR Assay for Quantification of Human Immunodeficiency Virus Type 1 DNA
A. Beloukas et al.
JOURNAL OF CLINICAL MICROBIOLOGY (2009)
Quantitation of HIV-1 group M proviral DNA using TaqMan MGB real-time PCR
Makiko Kondo et al.
JOURNAL OF VIROLOGICAL METHODS (2009)
HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation
Nicolas Chomont et al.
NATURE MEDICINE (2009)
Detecting HIV-1 integration by repetitive-sampling (Alu)under-bar-gag PCR
Megan K. Liszewski et al.
METHODS (2009)
Long-Term Control of HIV by CCR5 Delta32/Delta32 Stem-Cell Transplantaion
Gero Huetter et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
Cellular Levels of HIV Unspliced RNA from Patients on Combination Antiretroviral Therapy with Undetectable Plasma Viremia Predict the Therapy Outcome
Alexander O. Pasternak et al.
PLOS ONE (2009)
Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy
J. B. Dinoso et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
TLR5 stimulation is sufficient to trigger reactivation of latent HIV-1 provirus in T lymphoid cells and activate virus gene expression in central memory CD4(+) T cells
Sandra Thibault et al.
VIROLOGY (2009)
Closed chromatin architecture is induced by an RNA duplex targeting the HIV-1 promoter region
Kazuo Suzuki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Persistence of HIV in gut-associated lymphoid tissue despite long-term antiretroviral therapy
Tae-Wook Chun et al.
JOURNAL OF INFECTIOUS DISEASES (2008)
Resting Regulatory CD4 T Cells: A Site of HIV Persistence in Patients on Long-Term Effective Antiretroviral Therapy
Tu-Anh Tran et al.
PLOS ONE (2008)
A more precise HIV integration assay designed to detect small differences finds lower levels of integrated DNA in HAART treated patients
Jianqing J. Yu et al.
VIROLOGY (2008)
Addition of deoxynucleosides enhances human immunodeficiency virus type 1 integration and 2LTR formation in resting CD4+ T cells
Gabriela Plesa et al.
JOURNAL OF VIROLOGY (2007)
HIV-1 integrates into resting CD4+ T cells even at low inoculums as demonstrated with an improved assay for HIV-1 integration
Luis M. Agosto et al.
VIROLOGY (2007)
Apoptotic killing of HIV-1-infected macrophages is subverted by the viral envelope glycoprotein
Simon Swingler et al.
PLOS PATHOGENS (2007)
Immediate activation fails to rescue efficient human immunodeficiency virus replication in quiescent CD4+ T cells
Dimitrios N. Vatakis et al.
JOURNAL OF VIROLOGY (2007)
Residual human immunodeficiency virus type 1 viremia in some patients on Antiretroviral therapy is dominated by a small number of invariant clones rarely found in circulating CD4+ T cells
JR Bailey et al.
JOURNAL OF VIROLOGY (2006)
Sustained control of viremia following therapeutic immunization in chronically HIV-1-infected individuals
Y Lévy et al.
AIDS (2006)
Human immunodeficiency virus type 1 can establish latent infection in resting CD4+ T cells in the absence of activating stimuli
WJ Swiggard et al.
JOURNAL OF VIROLOGY (2005)
Depletion of latent HIV-1 infection in vivo: a proof-of-concept study
G Lehrman et al.
LANCET (2005)
Quantitative DNA proviral detection in HIV-1 patients treated with antiretroviral therapy
F Vitone et al.
JOURNAL OF CLINICAL VIROLOGY (2005)
Human immunodeficiency virus type 1 (HIV-1) proviral DNA load in purified CD4+ cells by LightCycler® real-time PCR -: art. no. 15
B Kabamba-Mukadi et al.
BMC INFECTIOUS DISEASES (2005)
Long HIV type 1 reverse transcripts can accumulate stably within resting CD4+ T cells while short ones are degraded
WJ Swiggard et al.
AIDS RESEARCH AND HUMAN RETROVIRUSES (2004)
Prostratin antagonizes HIV latency by activating NF-κB
SA Williams et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Analysis of human immunodeficiency virus type 1 gene expression in latently infected resting CD4+ T lymphocytes in vivo
M Hermankova et al.
JOURNAL OF VIROLOGY (2003)
Long-term follow-up studies confirm the stability of the latent reservoir for HIV-1 in resting CD4+ T cells
JD Siliciano et al.
NATURE MEDICINE (2003)
A sensitive, quantitative assay for human immunodeficiency virus type 1 integration
U O'Doherty et al.
JOURNAL OF VIROLOGY (2002)
Quantitation of human immunodeficiency virus type 1 DNA forms with the second template switch in peripheral blood cells predicts disease progression independently of plasma RNA load
LG Kostrikis et al.
JOURNAL OF VIROLOGY (2002)
Intrinsic stability of episomal circles formed during human immunodeficiency virus type 1 replication
TC Pierson et al.
JOURNAL OF VIROLOGY (2002)
Quantification of human immunodeficiency virus type 1 proviral load by a TaqMan real-time PCR assay
N Désiré et al.
JOURNAL OF CLINICAL MICROBIOLOGY (2001)
Characterization of chemokine receptor utilization of viruses in the latent reservoir for human immunodeficiency virus type 1
T Pierson et al.
JOURNAL OF VIROLOGY (2000)
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