期刊
TOXINS
卷 12, 期 4, 页码 -出版社
MDPI
DOI: 10.3390/toxins12040268
关键词
microcystins; toxicity and carcinogenicity; bacterial degradation; degrading mechanism
资金
- National Natural Science Foundation [81773393, 81502787]
- Central South University Innovation Driven Project [20170027010004]
Microcystins (MCs) classified as hepatotoxic and carcinogenic are the most commonly reported cyanobacterial toxins found in the environment. Microcystis sp. possessing a series of MC synthesis genes (mcyA-mcyJ) are well documented for their excessive abundance, numerous bloom occurrences and MC producing capacity. About 246 variants of MC which exert severe animal and human health hazards through the inhibition of protein phosphatases (PP1 and PP2A) have been characterized. To minimize and prevent MC health consequences, the World Health Organization proposed 1 mu g/L MC guidelines for safe drinking water quality. Further the utilization of bacteria that represent a promising biological treatment approach to degrade and remove MC from water bodies without harming the environment has gained global attention. Thus the present review described toxic effects and bacterial degradation of MCs.
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