相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Characterization and genotype-phenotype correlation of patients with Fanconi anemia in a multi-ethnic population
Orna Steinberg-Shemer et al.
HAEMATOLOGICA (2020)
FANCD2-FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair
Pablo Alcon et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2020)
Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex
Eunyoung Jeong et al.
NUCLEIC ACIDS RESEARCH (2020)
Regulation of R-loops and genome instability in Fanconi anemia
Yusuke Okamoto et al.
JOURNAL OF BIOCHEMISTRY (2019)
R-Loops as Cellular Regulators and Genomic Threats
Madzia P. Crossley et al.
MOLECULAR CELL (2019)
TRAIP is a master regulator of DNA interstrand crosslink repair
R. Alex Wu et al.
NATURE (2019)
Impeding the single-strand annealing pathway of DNA double-strand break repair by withaferin A-mediated FANCA degradation
Wenjun Liu et al.
DNA REPAIR (2019)
FANCD2 Binding to H4K20me2 via a Methyl-Binding Domain Is Essential for Efficient DNA Cross-Link Repair
Karissa L. Paquin et al.
MOLECULAR AND CELLULAR BIOLOGY (2019)
Elevated FANCA expression determines a worse prognosis in chronic lymphocytic leukemia and interferes with p53 function
Sara Bravo-Navas et al.
FASEB JOURNAL (2019)
The FANCM-BLM-TOP3A-RMI complex suppresses alternative lengthening of telomeres (ALT)
Robert Lu et al.
NATURE COMMUNICATIONS (2019)
DNA requirement in FANCD2 deubiquitination by USP1-UAF1-RAD51AP1 in the Fanconi anemia DNA damage response
Fengshan Liang et al.
NATURE COMMUNICATIONS (2019)
Phosphorylation of FANCD2 Inhibits the FANCD2/FANCI Complex and Suppresses the Fanconi Anemia Pathway in the Absence of DNA Damage
David Lopez-Martinez et al.
CELL REPORTS (2019)
SLX4IP acts with SLX4 and XPF-ERCC1 to promote interstrand crosslink repair
Huimin Zhang et al.
NUCLEIC ACIDS RESEARCH (2019)
Structure of the Fanconi anaemia monoubiquitin ligase complex
Shabih Shakeel et al.
NATURE (2019)
High expression of UBE2T predicts poor prognosis and survival in multiple myeloma
Weilong Zhang et al.
CANCER GENE THERAPY (2019)
FANCD2 protects genome stability by recruiting RNA processing enzymes to resolve R-loops during mild replication stress
Yusuke Okamoto et al.
FEBS JOURNAL (2019)
Binding of FANCI-FANCD2 Complex to RNA and R-Loops Stimulates Robust FANCD2 Monoubiquitination
Zhuobin Liang et al.
CELL REPORTS (2019)
PTEN deficiency sensitizes endometrioid endometrial cancer to compound PARP-PI3K inhibition but not PARP inhibition as monotherapy
X. Bian et al.
ONCOGENE (2018)
Two distinct conformational states define the interaction of human RAD51-ATP with single-stranded DNA
Ineke Brouwer et al.
EMBO JOURNAL (2018)
Replication Fork Reversal during DNA Interstrand Crosslink Repair Requires CMG Unloading
Ravindra Amunugama et al.
CELL REPORTS (2018)
FANCA Promotes DNA Double-Strand Break Repair by Catalyzing Single-Strand Annealing and Strand Exchange
Anaid Benitez et al.
MOLECULAR CELL (2018)
Structural basis for regulation of human acetyl-CoA carboxylase
Moritz Hunkeler et al.
NATURE (2018)
Rev7 dimerization is important for assembly and function of the Rev1/Polζ translesion synthesis complex
Alessandro A. Rizzo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Stitching up broken DNA ends by FANCA
Anna Palovcak et al.
MOLECULAR & CELLULAR ONCOLOGY (2018)
Specificity for deubiquitination of monoubiquitinated FANCD2 is driven by the N-terminus of USP1
Connor Arkinson et al.
LIFE SCIENCE ALLIANCE (2018)
DNA Repair Capacity in Multiple Pathways Predicts Chemoresistance in Glioblastoma Multiforme
Zachary D. Nagel et al.
CANCER RESEARCH (2017)
Cryo-EM structures of human RAD51 recombinase filaments during catalysis of DNA-strand exchange
Jingfei Xu et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
Cryo-EM structures of human RAD51 recombinase filaments during catalysis of DNA-strand exchange
Jingfei Xu et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2017)
Dynamic feature of mitotic arrest deficient 2-like protein 2 (MAD2L2) and structural basis for its interaction with chromosome alignment-maintaining phosphoprotein (CAMP)
Kodai Hara et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Biallelic mutations in the ubiquitin ligase RFWD3 cause Fanconi anemia
Kerstin Knies et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
Mind the Metal: A Fragment Library-Derived Zinc Impurity Binds the E2 Ubiquitin-Conjugating Enzyme Ube2T and Induces Structural Rearrangements
Francesca E. Morreale et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
Allosteric Targeting of the Fanconi Anemia Ubiquitin-Conjugating Enzyme Ube2T by Fragment Screening
Francesca E. Morreale et al.
JOURNAL OF MEDICINAL CHEMISTRY (2017)
Mechanism of Ubiquitination and Deubiquitination in the Fanconi Anemia Pathway
Sylvie van Twest et al.
MOLECULAR CELL (2017)
Maintenance of genome stability by Fanconi anemia proteins
Anna Palovcak et al.
CELL AND BIOSCIENCE (2017)
The FA Core Complex Contains a Homo-dimeric Catalytic Module for the Symmetric Mono-ubiquitination of FANCI-FANCD2
Paolo Swuec et al.
CELL REPORTS (2017)
Transcription-Replication Conflict Orientation Modulates R-Loop Levels and Activates Distinct DNA Damage Responses
Stephan Hamperl et al.
CELL (2017)
Defining a Cancer Dependency Map
Aviad Tsherniak et al.
CELL (2017)
Endogenous DNA Damage as a Source of Genomic Instability in Cancer
Anthony Tubbs et al.
CELL (2017)
Identification of the first small-molecule inhibitor of the REV7 DNA repair protein interaction
Marcelo L. Actis et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2016)
The USP1-UAF1 complex interacts with RAD51AP1 to promote homologous recombination repair
Scott Cukras et al.
CELL CYCLE (2016)
Recent Developments Using Small Molecules to Target RAD51: How to Best Modulate RAD51 for Anticancer Therapy?
Brian Budke et al.
CHEMMEDCHEM (2016)
Involvement of translesion synthesis DNA polymerases in DNA interstrand crosslink repair
Upasana Roy et al.
DNA REPAIR (2016)
Biallelic inactivation of REV7 is associated with Fanconi anemia
Dominique Bluteau et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
p97 Promotes a Conserved Mechanism of Helicase Unloading during DNA Cross-Link Repair
George Fullbright et al.
MOLECULAR AND CELLULAR BIOLOGY (2016)
Structure of BRCA1-BRCT/Abraxas Complex Reveals Phosphorylation-Dependent BRCT Dimerization at DNA Damage Sites
Qian Wu et al.
MOLECULAR CELL (2016)
The Fanconi anaemia pathway: newyplayers and new functions
Raphael Ceccaldi et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2016)
53BP1 fosters fidelity of homology-directed DNA repair
Fena Ochs et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
Repair Pathway Choices and Consequences at the Double-Strand Break
Raphael Ceccaldi et al.
TRENDS IN CELL BIOLOGY (2016)
Regulation of Single-Strand Annealing and its Role in Genome Maintenance
Ragini Bhargava et al.
TRENDS IN GENETICS (2016)
The functional status of DNA repair pathways determines the sensitization effect to cisplatin in non-small cell lung cancer cells
Ping Chen et al.
CELLULAR ONCOLOGY (2016)
53BP1 fosters fidelity of homology-directed DNA repair
Fena Ochs et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
Ranking novel cancer driving synthetic lethal gene pairs using TCGA data
Hao Ye et al.
ONCOTARGET (2016)
A High-Throughput Screening Strategy to Identify Protein-Protein Interaction Inhibitors That Block the Fanconi Anemia DNA Repair Pathway
Andrew F. Voter et al.
JOURNAL OF BIOMOLECULAR SCREENING (2016)
Peptide Library Approach to Uncover Phosphomimetic Inhibitors of the BRCA1 C-Terminal Domain
E. Railey White et al.
ACS CHEMICAL BIOLOGY (2015)
Fanconi anemia: a model disease for studies on human genetics and advanced therapeutics
Massimo Bogliolo et al.
CURRENT OPINION IN GENETICS & DEVELOPMENT (2015)
Regulation of the Rev1-pol ζ complex during bypass of a DNA interstrand cross-link
Magda Budzowska et al.
EMBO JOURNAL (2015)
The Cerebro-oculo-facio-skeletal Syndrome Point Mutation F231L in the ERCC1 DNA Repair Protein Causes Dissociation of the ERCC1-XPF Complex
Maryam Faridounnia et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
The Fanconi Anemia Pathway Maintains Genome Stability by Coordinating Replication and Transcription
Rebekka A. Schwab et al.
MOLECULAR CELL (2015)
Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair
Raphael Ceccaldi et al.
NATURE (2015)
DNA interstrand cross-link repair requires replication-fork convergence
Jieqiong Zhang et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
Naturally occurring FANCF-Hes1 complex inhibitors from Wrightia religiosa
Midori A. Arai et al.
MEDCHEMCOMM (2015)
DNA interstrand cross-link repair requires replication-fork convergence
Jieqiong Zhang et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
The Fanconi Anemia Pathway Protects Genome Integrity from R-loops
Mara L. Garcia-Rubio et al.
PLOS GENETICS (2015)
Biallelic Mutations in BRCA1 Cause a New Fanconi Anemia Subtype
Sarah L. Sawyer et al.
CANCER DISCOVERY (2015)
Update of the human and mouse Fanconi anemia genes
Hongbin Dong et al.
HUMAN GENOMICS (2015)
The Fanconi anemia ID2 complex: Dueling saxes at the crossroads
Rebecca A. Boisvert et al.
CELL CYCLE (2014)
A double-edged sword: R loops as threats to genome integrity and powerful regulators of gene expression
Konstantina Skourti-Stathaki et al.
GENES & DEVELOPMENT (2014)
Mouse SLX4 Is a Tumor Suppressor that Stimulates the Activity of the Nuclease XPF-ERCC1 in DNA Crosslink Repair
Michael R. G. Hodskinson et al.
MOLECULAR CELL (2014)
BRCA2 inhibition enhances cisplatin-mediated alterations in tumor cell proliferation, metabolism, and metastasis
Mateusz Rytelewski et al.
MOLECULAR ONCOLOGY (2014)
Damage-dependent regulation of MUS81-EME1 by Fanconi anemia complementation group A protein
Anaid Benitez et al.
NUCLEIC ACIDS RESEARCH (2014)
The Fanconi anemia pathway has a dual function in Dickkopf-1 transcriptional repression
Caroline C. Huard et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Structure of the Human FANCL RING-Ube2T Complex Reveals Determinants of Cognate E3-E2 Selection
Charlotte Hodson et al.
STRUCTURE (2014)
Cancer-specific defects in DNA repair pathways as targets for personalized therapeutic approaches
Felix Dietlein et al.
TRENDS IN GENETICS (2014)
FANCD2 and CtIP Cooperate to Repair DNA Interstrand Crosslinks
Olga Murina et al.
CELL REPORTS (2014)
Modularized Functions of the Fanconi Anemia Core Complex
Yaling Huang et al.
CELL REPORTS (2014)
Mutations in ERCC4, Encoding the DNA-Repair Endonuclease XPF, Cause Fanconi Anemia
Massimo Bogliolo et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2013)
Structural Basis for the BRCA1 BRCT Interaction with the Proteins ATRIP and BAAT1
Xuying Liu et al.
BIOCHEMISTRY (2013)
Regulation of multiple DNA repair pathways by the Fanconi anemia protein SLX4
Yonghwan Kim et al.
BLOOD (2013)
Learning from a paradox: recent insights into Fanconi anaemia through studying mouse models
Sietske T. Bakker et al.
DISEASE MODELS & MECHANISMS (2013)
An Optimized RAD51 Inhibitor That Disrupts Homologous Recombination without Requiring Michael Acceptor Reactivity
Brian Budke et al.
JOURNAL OF MEDICINAL CHEMISTRY (2013)
Fanconi anaemia and the repair of Watson and Crick DNA crosslinks
Molly C. Kottemann et al.
NATURE (2013)
Structural insights into the functions of the FANCM-FAAP24 complex in DNA repair
Hui Yang et al.
NUCLEIC ACIDS RESEARCH (2013)
Architecture and DNA Recognition Elements of the Fanconi Anemia FANCM-FAAP24 Complex
Rachel Coulthard et al.
STRUCTURE (2013)
Assessment of FANCD2 nuclear foci formation in paraffin-embedded tumors: a potential patient-enrichment strategy for treatment with DNA interstrand crosslinking agents
Wenrui Duan et al.
TRANSLATIONAL RESEARCH (2013)
Advances in Understanding the Complex Mechanisms of DNA Interstrand Cross-Link Repair
Cheryl Clauson et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)
SLX4 Assembles a Telomere Maintenance Toolkit by Bridging Multiple Endonucleases with Telomeres
Bingbing Wan et al.
CELL REPORTS (2013)
PTEN Deletion in Prostate Cancer Cells Does Not Associate with Loss of RAD51 Function: Implications for Radiotherapy and Chemotherapy
Michael Fraser et al.
CLINICAL CANCER RESEARCH (2012)
Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway
Hyungjin Kim et al.
GENES & DEVELOPMENT (2012)
Fanconi Anemia Complementation Group A (FANCA) Protein Has Intrinsic Affinity for Nucleic Acids with Preference for Single-stranded Forms
Fenghua Yuan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Structural Basis of Recruitment of DNA Polymerase ζ by Interaction between REV1 and REV7 Proteins
Sotaro Kikuchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
A Human Ubiquitin Conjugating Enzyme (E2)-HECT E3 Ligase Structure-function Screen
Yi Sheng et al.
MOLECULAR & CELLULAR PROTEOMICS (2012)
Fanconi anemia proteins FANCD2 and FANCI exhibit different DNA damage responses during S-phase
Archana Sareen et al.
NUCLEIC ACIDS RESEARCH (2012)
Defining the molecular interface that connects the Fanconi anemia protein FANCM to the Bloom syndrome dissolvasome
Kelly A. Hoadley et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
The Structure of the XPF-ssDNA Complex Underscores the Distinct Roles of the XPF and ERCC1 Helix-Hairpin-Helix Domains in ss/ds DNA Recognition
Devashish Das et al.
STRUCTURE (2012)
The structure of the FANCM-MHF complex reveals physical features for functional assembly
Yuyong Tao et al.
NATURE COMMUNICATIONS (2012)
Structural insights into the assembly of human translesion polymerase complexes
Wei Xie et al.
PROTEIN & CELL (2012)
Identification of Specific Inhibitors of Human RAD51 Recombinase Using High-Throughput Screening
Fei Huang et al.
ACS CHEMICAL BIOLOGY (2011)
Double-Strand Break End Resection and Repair Pathway Choice
Lorraine S. Symington et al.
ANNUAL REVIEW OF GENETICS, VOL 45 (2011)
Impact of BRCA1 BRCT Domain Missense Substitutions on Phosphopeptide Recognition
Nicolas Coquelle et al.
BIOCHEMISTRY (2011)
Myelodysplasia and leukemia of Fanconi anemia are associated with a specific pattern of genomic abnormalities that includes cryptic RUNX1/AML1 lesions
Samuel Quentin et al.
BLOOD (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
Orchestrating the nucleases involved in DNA interstrand cross-link (ICL) repair
Blanka Sengerova et al.
CELL CYCLE (2011)
Human SNM1A and XPF-ERCC1 collaborate to initiate DNA interstrand cross-link repair
Anderson T. Wang et al.
GENES & DEVELOPMENT (2011)
R-loop-mediated genomic instability is caused by impairment of replication fork progression
Wenjian Gan et al.
GENES & DEVELOPMENT (2011)
Molecular Basis of BACH1/FANCJ Recognition by TopBP1 in DNA Replication Checkpoint Control
Charles Chung Yun Leung et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Structural Analysis of Human FANCL, the E3 Ligase in the Fanconi Anemia Pathway
Charlotte Hodson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
DNA damage induced by endogenous aldehydes: Current state of knowledge
Georgia-Persephoni Voulgaridou et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2011)
Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice
Frederic Langevin et al.
NATURE (2011)
Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway
Ivan V. Rosado et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2011)
Nonhomologous end joining drives poly(ADP-ribose) polymerase (PARP) inhibitor lethality in homologous recombination-deficient cells
Anand G. Patel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway
Kimiyo N. Yamamoto et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Structure of the FANCI-FANCD2 Complex: Insights into the Fanconi Anemia DNA Repair Pathway
Woo Joo et al.
SCIENCE (2011)
DNA interstrand crosslink repair and cancer
Andrew J. Deans et al.
NATURE REVIEWS CANCER (2011)
Identification of KIAA1018/FAN1, a DNA Repair Nuclease Recruited to DNA Damage by Monoubiquitinated FANCD2
Craig MacKay et al.
CELL (2010)
Human KIAA1018/FAN1 localizes to stalled replication forks via its ubiquitin-binding domain
Robert D. Shereda et al.
CELL CYCLE (2010)
The role of FAN1 nuclease in the Fanconi anemia pathway
Maria Castella et al.
CELL CYCLE (2010)
Crystal Structure of Human REV7 in Complex with a Human REV3 Fragment and Structural Implication of the Interaction between DNA Polymerase ζ and REV1
Kodai Hara et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
A Genetic Screen Identifies FAN1, a Fanconi Anemia-Associated Nuclease Necessary for DNA Interstrand Crosslink Repair
Agata Smogorzewska et al.
MOLECULAR CELL (2010)
Preventing Nonhomologous End Joining Suppresses DNA Repair Defects of Fanconi Anemia
Adele Adamo et al.
MOLECULAR CELL (2010)
Genomic instability - an evolving hallmark of cancer
Simona Negrini et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2010)
KIAA1018/FAN1 nuclease protects cells against genomic instability induced by interstrand cross-linking agents
Kazunori Yoshikiyo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Ku70 Corrupts DNA Repair in the Absence of the Fanconi Anemia Pathway
Paul Pace et al.
SCIENCE (2010)
FAN1 Acts with FANCI-FANCD2 to Promote DNA Interstrand Cross-Link Repair
Ting Liu et al.
SCIENCE (2010)
Comparison of the Structures and Peptide Binding Specificities of the BRCT Domains of MDC1 and BRCA1
Stephen J. Campbell et al.
STRUCTURE (2010)
Synthetic lethal targeting of PTEN mutant cells with PARP inhibitors
Ana M. Mendes-Pereira et al.
EMBO MOLECULAR MEDICINE (2009)
Structural basis for recruitment of BRCA2 by PALB2
Antony W. Oliver et al.
EMBO REPORTS (2009)
The Fanconi Anemia Core Complex Acts as a Transcriptional Co-regulator in Hairy Enhancer of Split 1 Signaling
Cedric S. Tremblay et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
FANCI Protein Binds to DNA and Interacts with FANCD2 to Recognize Branched Structures
Fenghua Yuan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
FANCI Binds Branched DNA and Is Monoubiquitinated by UBE2T-FANCL
Simonne Longerich et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
XPF-ERCC1 Participates in the Fanconi Anemia Pathway of Cross-Link Repair
Nikhil Bhagwat et al.
MOLECULAR AND CELLULAR BIOLOGY (2009)
Monoketone analogs of curcumin, a new class of Fanconi anemia pathway inhibitors
Igor Landais et al.
MOLECULAR CANCER (2009)
Mouse models of Fanconi anemia
Kalindi Parmar et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2009)
Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from BRCA Mutation Carriers.
Peter C. Fong et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
The Fanconi Anemia Pathway Promotes Replication-Dependent DNA Interstrand Cross-Link Repair
Puck Knipscheer et al.
SCIENCE (2009)
Interstrand DNA cross-links induced by α,β-unsaturated aldehydes derived from lipid peroxidation and environmental sources
Michael P. Stone et al.
ACCOUNTS OF CHEMICAL RESEARCH (2008)
Structural evidence for direct interactions between the BRCT domains of human BRCA1 and a phospho-peptide from human ACC1
Yang Shen et al.
BIOCHEMISTRY (2008)
HES1 is a novel interactor of the Fanconi anemia core complex
Cedric S. Tremblay et al.
BLOOD (2008)
FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway
Masamichi Ishiai et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2008)
Coordinate regulation of Fanconi anemia gene expression occurs through the Rb/E2F pathway
E. E. Hoskins et al.
ONCOGENE (2008)
The HhH domain of the human DNA repair protein XPF forms stable homodimers
Devashish Das et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2008)
DNA repair pathways as targets for cancer therapy
Thomas Helleday et al.
NATURE REVIEWS CANCER (2008)
Cells deficient in the FANC/BRCA pathway are hypersensitive to plasma levels of formaldehyde
John R. Ridpath et al.
CANCER RESEARCH (2007)
The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks
Katsuhiro Hanada et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)
Proteasome function is required for DNA damage response and Fanconi anemia pathway activation
Celine Jacquemont et al.
CANCER RESEARCH (2007)
FANCI is a second monoubiquitinated member of the Fanconi anemia pathway
Ashley E. Sims et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)
Hsp90 regulates the Fanconi anemia DNA damage response pathway
Tsukasa Oda et al.
BLOOD (2007)
Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated
Richard D. Kennedy et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Direct cellular responses to platinum-induced DNA damage
Yongwon Jung et al.
CHEMICAL REVIEWS (2007)
The Fanconi anemia (FA) pathway confers glioma resistance to DNA alkylating agents
Clark C. Chen et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2007)
Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair
Agata Smogorzewska et al.
CELL (2007)
Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM
Alberto Ciccia et al.
MOLECULAR CELL (2007)
Structural determinants of human FANCF protein that function in the assembly of a DNA damage signaling complex
Przemyslaw Kowal et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
The structure-specific endonuclease Mus81-Eme1 promotes conversion of interstrand DNA crosslinks into double-strands breaks
Katsuhiro Hanada et al.
EMBO JOURNAL (2006)
Chemosensitization to cisplatin by inhibitors of the Fanconi anemia/BRCA pathway
D Chirnomas et al.
MOLECULAR CANCER THERAPEUTICS (2006)
BRCA1: cell cycle checkpoint, genetic instability, DNA damage response and cancer evolution
CX Deng
NUCLEIC ACIDS RESEARCH (2006)
The Fanconi Anemia/BRCA pathway: new faces in the crowd
RD Kennedy et al.
GENES & DEVELOPMENT (2005)
The structure of the human ERCC1/XPF interaction domains reveals a complementary role for the two proteins in nucleotide excision repair
K Tripsianes et al.
STRUCTURE (2005)
In vivo therapeutic responses contingent on Fanconi anemia/BRCA2 status of the tumor
MS van der Heijden et al.
CLINICAL CANCER RESEARCH (2005)
Structural basis for cell cycle checkpoint control by the BRCA1-CtIP complex
AK Varma et al.
BIOCHEMISTRY (2005)
Crystal structure and DNA binding functions of ERCC1, a subunit of the DNA structure-specific endonuclease XPF-ERCC1
OV Tsodikov et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
The FA/BRCA pathway is involved in melphalan-induced DNA interstrand cross-link repair and accounts for melphalan resistance in multiple myeloma cells
Q Chen et al.
BLOOD (2005)
Direct DNA binding activity of the Fanconi anemia D2 protein
WH Park et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Fanconi anemia complementation group D2 (FANCD2) functions independently of BRCA2- and RAD51-associated homologous recombination in response to DNA damage
A Ohashi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Human fanconi anemia monoubiquitination pathway promotes homologous DNA repair
K Nakanishi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Solution structure, backbone dynamics, and association behavior of the C-terminal BRCT domain from the breast cancer-associated protein BRCA1
OJ Gaiser et al.
BIOCHEMISTRY (2004)
Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1
RS Williams et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2004)
Molecular mechanisms of mammalian DNA repair and the DNA damage checkpoints
A Sancar et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2004)
Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer
JA Clapperton et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2004)
Structure of the BRCT repeats of BRCA1 bound to a BACH1 phosphopeptide: Implications for signaling
EN Shiozaki et al.
MOLECULAR CELL (2004)
Interstrand crosslink-induced radials form between non-homologous chromosomes, but are absent in sex chromosomes
AEH Newell et al.
DNA REPAIR (2004)
Disruption of the Fanconi anemia-BRCA pathway in cisplatin-sensitive ovarian tumors
T Taniguchi et al.
NATURE MEDICINE (2003)
Structural consequences of a cancer-causing BRCA1-BRCT missense mutation
RS Williams et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Insights into DNA recombination from the structure of a RAD51-BRCA2 complex
L Pellegrini et al.
NATURE (2002)
Structure of a BRCA1-BARD1 heterodimeric RING-RING complex
PS Brzovic et al.
NATURE STRUCTURAL BIOLOGY (2001)
Crystal structure of the BRCT repeat region from the breast cancer-associated protein BRCA1
RS Williams et al.
NATURE STRUCTURAL BIOLOGY (2001)
分享论文
