相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Stability of the Antimalarial Drug Dihydroartemisinin under Physiologically Relevant Conditions: Implications for Clinical Treatment and Pharmacokinetic and In Vitro Assays
Silvia Parapini et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2015)
The survival times of malaria-infected mice are prolonged more by several new two-carbon-linked artemisinin-derived dimer carbamates than by the trioxane antimalarial drug artemether
Ryan C. Conyers et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2014)
Artemisinin resistance - modelling the potential human and economic costs
Yoel Lubell et al.
MALARIA JOURNAL (2014)
A molecular marker of artemisinin-resistant Plasmodium falciparum malaria
Frederic Ariey et al.
NATURE (2014)
Glucocorticosteroids in Nano-Sterically Stabilized Liposomes Are Efficacious for Elimination of the Acute Symptoms of Experimental Cerebral Malaria
Judith H. Waknine-Grinberg et al.
PLOS ONE (2013)
Anticancer Properties of Distinct Antimalarial Drug Classes
Rob Hooft van Huijsduijnen et al.
PLOS ONE (2013)
Comparative Ex Vivo Activity of Novel Endoperoxides in Multidrug-Resistant Plasmodium falciparum and P. vivax
Jutta Marfurt et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2012)
Interactions between Artemisinins and other Antimalarial Drugs in Relation to the Cofactor Model-A Unifying Proposal for Drug Action
Richard K. Haynes et al.
CHEMMEDCHEM (2012)
Emergence of artemisinin-resistant malaria on the western border of Thailand: a longitudinal study
Aung Pyae Phyo et al.
LANCET (2012)
The Activities of Current Antimalarial Drugs on the Life Cycle Stages of Plasmodium: A Comparative Study with Human and Rodent Parasites
Michael Delves et al.
PLOS MEDICINE (2012)
In vitro study of the anti-cancer effects of artemisone alone or in combination with other chemotherapeutic agents
Andrew M. Gravett et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2011)
Reactions of Antimalarial Peroxides with Each of Leucomethylene Blue and Dihydroflavins: Flavin Reductase and the Cofactor Model Exemplified
Richard K. Haynes et al.
CHEMMEDCHEM (2011)
Review of the clinical pharmacokinetics of artesunate and its active metabolite dihydroartemisinin following intravenous, intramuscular, oral or rectal administration
Carrie A. Morris et al.
MALARIA JOURNAL (2011)
Dihydroartemisinin improves the efficiency of chemotherapeutics in lung carcinomas in vivo and inhibits murine Lewis lung carcinoma cell line growth in vitro
Hui-Jun Zhou et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2010)
Facile Oxidation of Leucomethylene Blue and Dihydroflavins by Artemisinins: Relationship with Flavoenzyme Function and Antimalarial Mechanism of Action
Richard K. Haynes et al.
CHEMMEDCHEM (2010)
The pharmaceutical death-ride of dihydroartemisinin
Frans Herwig Jansen
MALARIA JOURNAL (2010)
Artemisone effective against murine cerebral malaria
Judith H. Waknine-Grinberg et al.
MALARIA JOURNAL (2010)
Artemisone and Artemiside Control Acute and Reactivated Toxoplasmosis in a Murine Model
Ildiko R. Dunay et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2009)
Evaluation of Artemisone Combinations in Aotus Monkeys Infected with Plasmodium falciparum
Nicanor Obaldia et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2009)
Fre Is the Major Flavin Reductase Supporting Bioluminescence from Vibrio harveyi Luciferase in Escherichia coli
Zachary T. Campbell et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
New medicines to improve control and contribute to the eradication of malaria
Timothy N. C. Wells et al.
NATURE REVIEWS DRUG DISCOVERY (2009)
Computational and experimental studies on the catalytic mechanism of biliverdin-IXβ reductase
Liam J. Smith et al.
BIOCHEMICAL JOURNAL (2008)
Artemisinins: their growing importance in medicine
Sanjeev Krishna et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2008)
Understanding artemisinin-induced brainstem neurotoxicity
Raymond F. Genovese et al.
ARCHIVES OF TOXICOLOGY (2008)
Artesunate and Dihydroartemisinin (DHA): Unusual Decomposition Products Formed under Mild Conditions and Comments on the Fitness of DHA as an Antimalarial Drug
Richard K. Haynes et al.
CHEMMEDCHEM (2007)
Role of Transferrin Receptor and the ABC Transporters ABCB6 and ABCB7 for Resistance and Differentiation of Tumor Cells towards Artesunate
Gerhard Kelter et al.
PLOS ONE (2007)
Antimalarial efficacy and drug interactions of the novel semi-synthetic endoperoxide artemisone in vitro and in vivo
L. Vivas et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2007)
Simulation study of methemoglobin reduction in erythrocytes - Differential contributions of two pathways to tolerance to oxidative stress
Ayako Kinoshita et al.
FEBS JOURNAL (2007)
Are currently deployed artemisinins neurotoxic?
Stephen Toovey
TOXICOLOGY LETTERS (2006)
Recent progress in the synthesis of artemisinin and its derivatives
BJ Kim et al.
ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL (2006)
Artesunate versus quinine for severe falciparum malaria
S Toovey
LANCET (2006)
Artemisone - A highly active antimalarial drug of the artemisinin class
RK Haynes et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2006)
From artemisinin to new artemisinin antimalarials: Biosynthesis, extraction, old and new derivatives, stereochemistry and medicinal chemistry requirements
Richard K. Haynes
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2006)
Artemisinins
CJ Woodrow et al.
POSTGRADUATE MEDICAL JOURNAL (2005)
Artemisinin derivatives: toxic for laboratory animals, safe for humans?
T Gordi et al.
TOXICOLOGY LETTERS (2004)
Response to: artemisinin derivatives: toxic for laboratory animals, safe for humans?
S Toovey et al.
TOXICOLOGY LETTERS (2004)
Highly antimalaria-active artemisinin derivatives: Biological activity does not correlate with chemical reactivity
RK Haynes et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2004)
Superior protection against malaria and melanoma metastases by a C-glycoside analogue of the natural killer T cell ligand alpha-galactosylceramide
J Schmieg et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Penetration of dihydroartemisinin into cerebrospinal fluid after administration of intravenous artesunate in severe falciparum malaria
TME Davis et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2003)
Glucuronidation of dihydroartemisinin in vivo and by human liver microsomes and expressed UDP-glucuronosyltransferases
KF Ilett et al.
DRUG METABOLISM AND DISPOSITION (2002)
Relative bioavailability of artesunate and dihydroartemisinin: Investigations in the isolated perfused rat liver and in healthy Caucasian volunteers
KT Batty et al.
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE (2002)
Neurotoxic mode of action of artemisinin
G Schmuck et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2002)
Artemisinin and derivatives: the future for malaria treatment?
RK Haynes
CURRENT OPINION IN INFECTIOUS DISEASES (2001)
Insight into the chemistry of flavin reduction and oxidation in Escherichia coli dihydroorotate dehydrogenase obtained by rapid reaction studies
BA Palfey et al.
BIOCHEMISTRY (2001)
Enzymes in pancreatic islets that use NADP(H) as a cofactor including evidence for plasma membrane aldehyde reductase
M Laclau et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2001)
Syntheses and antimalarial activities of 10-substituted deoxoartemisinins
JY Ma et al.
JOURNAL OF MEDICINAL CHEMISTRY (2000)
Behavioral and neural toxicity of the artemisinin antimalarial, arteether, but not artesunate and artelinate, in rats
RE Genovese et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2000)