期刊
CHEMISTRY-AN ASIAN JOURNAL
卷 11, 期 16, 页码 2240-2245出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/asia.201600797
关键词
biosensors; boronate affinity; glucose; molecular imprinting; self-assembly
资金
- National Natural Science Foundation of China [21377172, 21225731, 21477166, 21527813]
- NSF of Guangdong Province [S2013030013474]
A biocompatible probe for specific glucose recognition is based on photoinitiated boronate affinity-molecular imprinted polymers (BA-MIPs). The unique pre-self-assembly between glucose and boronic acids creates glucose-specific memory cavities in the BA-MIPs coating. As a result, the binding constant toward glucose was enhanced by three orders of magnitude. The BA-MIPs probe was applied to glucose determination in serum and urine and implanted into plant tissues for low-destructive and long-term in vivo continuous glucose monitoring.
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