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Ignacio Melero et al.
CANCER DISCOVERY (2014)
Targeting Fibroblast Activation Protein in Tumor Stroma with Chimeric Antigen Receptor T Cells Can Inhibit Tumor Growth and Augment Host Immunity without Severe Toxicity
Liang-Chuan S. Wang et al.
CANCER IMMUNOLOGY RESEARCH (2014)
The critical role of IL-15-PI3K-mTOR pathway in natural killer cell effector functions
Neethi Nandagopal et al.
FRONTIERS IN IMMUNOLOGY (2014)
Cancer-associated fibroblasts as another polarized cell type of the tumor microenvironment
Martin Augsten
FRONTIERS IN ONCOLOGY (2014)
Utilizing Cytokines to Function-Enable Human NK Cells for the Immunotherapy of Cancer
Rizwan Romee et al.
SCIENTIFICA (2014)
NK cell CD16 surface expression and function is regulated by a disintegrin and metalloprotease-17 (ADAM17)
Rizwan Romee et al.
BLOOD (2013)
An Inflammatory Mediator, Prostaglandin E2, in Colorectal Cancer
Dingzhi Wang et al.
CANCER JOURNAL (2013)
A Chimeric Receptor with NKG2D Specificity Enhances Natural Killer Cell Activation and Killing of Tumor Cells
Yu-Hsiang Chang et al.
CANCER RESEARCH (2013)
Recruitment of Grb2 and SHIP1 by the ITT-like motif of TIGIT suppresses granule polarization and cytotoxicity of NK cells
S. Liu et al.
CELL DEATH AND DIFFERENTIATION (2013)
Hypoxia downregulates the expression of activating receptors involved in NK-cell-mediated target cell killing without affecting ADCC
Mirna Balsamo et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2013)
Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function
Madhusudhanan Sukumar et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Membrane-Type 6 Matrix Metalloproteinase Regulates the Activation-Induced Downmodulation of CD16 in Human Primary NK Cells
Giovanna Peruzzi et al.
JOURNAL OF IMMUNOLOGY (2013)
Tumor-Derived Lactate Modifies Antitumor Immune Response: Effect on Myeloid-Derived Suppressor Cells and NK Cells
Zaheed Husain et al.
JOURNAL OF IMMUNOLOGY (2013)
Neuroblastoma-Derived TGF-β1 Modulates the Chemokine Receptor Repertoire of Human Resting NK Cells
Roberta Castriconi et al.
JOURNAL OF IMMUNOLOGY (2013)
KLRG1 Negatively Regulates Natural Killer Cell Functions through the Akt Pathway in Individuals with Chronic Hepatitis C Virus Infection
Jia M. Wang et al.
JOURNAL OF VIROLOGY (2013)
Tumor glycolysis as a target for cancer therapy: progress and prospects
Shanmugasundaram Ganapathy-Kanniappan et al.
MOLECULAR CANCER (2013)
Colorectal carcinoma-derived fibroblasts modulate natural killer cell phenotype and antitumor cytotoxicity
Tuanjie Li et al.
MEDICAL ONCOLOGY (2013)
CD73 promotes anthracycline resistance and poor prognosis in triple negative breast cancer
Sherene Loi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Blockade of A2A receptors potently suppresses the metastasis of CD73+ tumors
Paul A. Beavis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Generation of Soluble NKG2D Ligands: Proteolytic Cleavage, Exosome Secretion and Functional Implications
G. Chitadze et al.
SCANDINAVIAN JOURNAL OF IMMUNOLOGY (2013)
Lung tumor microenvironment induces specific gene expression signature in intratumoral NK cells
Melanie Gillard-Bocquet et al.
FRONTIERS IN IMMUNOLOGY (2013)
Immunity, inflammation and cancer: a leading role for adenosine
Luca Antonioli et al.
NATURE REVIEWS CANCER (2013)
Tim-3 marks human natural killer cell maturation and suppresses cell-mediated cytotoxicity
Lishomwa C. Ndhlovu et al.
BLOOD (2012)
NKG2D ligand tumor expression and association with clinical outcome in early breast cancer patients: an observational study
Esther M. de Kruijf et al.
BMC CANCER (2012)
Expression of IL-15 in NK cells results in rapid enrichment and selective cytotoxicity of gene-modified effectors that carry a tumor-specific antigen receptor
Christiane Sahm et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2012)
Paclitaxel Enhances Therapeutic Efficacy of the F8-IL2 Immunocytokine to EDA-Fibronectin-Positive Metastatic Human Melanoma Xenografts
Michele Moschetta et al.
CANCER RESEARCH (2012)
Decreased NKG2D expression on NK cells correlates with impaired NK cell function in patients with gastric cancer
Hiroaki Saito et al.
GASTRIC CANCER (2012)
Gr-1+CD11b+cells are responsible for tumor promoting effect of TGF-ß in breast cancer progression
Zhaoyang Li et al.
INTERNATIONAL JOURNAL OF CANCER (2012)
Autophagy and cancer - issues we need to digest
Emma Y. Liu et al.
JOURNAL OF CELL SCIENCE (2012)
NK cells engineered to express a GD2-specific antigen receptor display built-in ADCC-like activity against tumour cells of neuroectodermal origin
Ruth Esser et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2012)
Regulation of Immune Responses by Prostaglandin E-2
Pawel Kalinski
JOURNAL OF IMMUNOLOGY (2012)
Modulation of Host Natural Killer Cell Functions in Breast Cancer via Prostaglandin E2 Receptors EP2 and EP4
Dawn M. Holt et al.
JOURNAL OF IMMUNOTHERAPY (2012)
Transcript signature predicts tissue NK cell content and defines renal cell carcinoma subgroups independent of TNM staging
Judith Eckl et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2012)
Combination delivery of TGF-β inhibitor and IL-2 by nanoscale liposomal polymeric gels enhances tumour immunotherapy
Jason Park et al.
NATURE MATERIALS (2012)
Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell-cell adhesion and signaling mechanism that requires cis-trans receptor clustering
Katharina F. Stengel et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Inflammation restraining effects of prostaglandin E2 on natural killer-dendritic cell (NK-DC) interaction are imprinted during DC maturation
Catharina H. M. J. Van Elssen et al.
BLOOD (2011)
Profound Coordinated Alterations of Intratumoral NK Cell Phenotype and Function in Lung Carcinoma
Sophia Platonova et al.
CANCER RESEARCH (2011)
Immune microenvironments in solid tumors: new targets for therapy
Stephen L. Shiao et al.
GENES & DEVELOPMENT (2011)
Interleukin (IL)-2 and IL-15 have different effects on human natural killer lymphocytes
Anne-Helene Pillet et al.
HUMAN IMMUNOLOGY (2011)
Human breast cancer cells enhance self tolerance by promoting evasion from NK cell antitumor immunity
Emilie Mamessier et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
IL-12 Enhances the Antitumor Actions of Trastuzumab via NK Cell IFN-γ Production
Alena Cristina Jaime-Ramirez et al.
JOURNAL OF IMMUNOLOGY (2011)
Natural Killer Cells and Solid Tumors
Ana Stojanovic et al.
JOURNAL OF INNATE IMMUNITY (2011)
High expression of HLA-E in colorectal carcinoma is associated with a favorable prognosis
Maria Benevolo et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2011)
Cytokine regulation of natural killer cell effector functions
Norberto W. Zwirner et al.
BIOFACTORS (2010)
TGF-beta downregulates the activating receptor NKG2D on NK cells and CD8(+) T cells glioma patients
Courtney A. Crane et al.
NEURO-ONCOLOGY (2010)
Extracellular adenosine triphosphate and adenosine in cancer
J. Stagg et al.
ONCOGENE (2010)
Cancer associated fibroblasts in cancer pathogenesis
Omar E. Franco et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2010)
Polarization of Tumor-Associated Neutrophil Phenotype by TGF-β: N1 versus N2 TAN
Zvi G. Fridlender et al.
CANCER CELL (2009)
The COX-2/PGE(2) pathway: key roles in the hallmarks of cancer and adaptation to the tumour microenvironment
Alexander Greenhough et al.
CARCINOGENESIS (2009)
Cancer-Expanded Myeloid-Derived Suppressor Cells Induce Anergy of NK Cells through Membrane-Bound TGF-beta 1
Hequan Li et al.
JOURNAL OF IMMUNOLOGY (2009)
Autophagy in tumour suppression and promotion
Andreas Brech et al.
MOLECULAR ONCOLOGY (2009)
Melanoma-associated fibroblasts modulate NK cell phenotype and antitumor cytotoxicity
Mirna Balsamo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity
Noa Stanietsky et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Natural killer cells infiltrating human nonsmall-cell lung cancer are enriched in CD56BrightCD16- cells and display an impaired capability to kill tumor cells
Paolo Carrega et al.
CANCER (2008)
Natural Killer Cell Accumulation in Tumors Is Dependent on IFN-γ and CXCR3 Ligands
Marco Wendel et al.
CANCER RESEARCH (2008)
IL-15Rα chaperones IL-15 to stable dendritic cell membrane complexes that activate NK cells via trans presentation
Erwan Mortier et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
TGF-β utilizes SMAD3 to inhibit CD16-mediated IFN-γ production and antibody-dependent cellular cytotoxicity in human NK cells
Rossana Trotta et al.
JOURNAL OF IMMUNOLOGY (2008)
Interleukin 15-mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1
Nicholas D. Huntington et al.
NATURE IMMUNOLOGY (2007)
Immune surveillance of tumors
Jeremy B. Swann et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Cytotoxic markers and frequency predict functional capacity of natural killer cells infiltrating renal cell carcinoma
JS Schleypen et al.
CLINICAL CANCER RESEARCH (2006)
Galectin-1: A link between tumor hypoxia and tumor immune privilege
QT Le et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
The cell biology of the human natural killer cell CD94/NKG2A inhibitory receptor
F Borrego et al.
MOLECULAR IMMUNOLOGY (2005)
Pilot study of the mechanism of action of preoperative trastuzumab in patients with primary operable breast tumors overexpressing HER2
R Gennari et al.
CLINICAL CANCER RESEARCH (2004)
The inhibitory NK cell receptor CD94/NKG2A and the activating receptor CD94/NKG2C bind the top of HLA-E through mostly shared but partly distinct sets of HLA-E residues
H Wada et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2004)
Elevated TGF-β1 secretion and down-modulation of NKG2D underlies impaired NK cytotoxicity in cancer patients
JC Lee et al.
JOURNAL OF IMMUNOLOGY (2004)
Renal cell carcinoma-infiltrating natural killer cells express differential repertoires of activating and inhibitory receptors and are inhibited by specific HLA class I allotypes
JS Schleypen et al.
INTERNATIONAL JOURNAL OF CANCER (2003)
IL-21 in synergy with IL-15 or IL-18 enhances IFN-γ production in human NK and T cells
M Strengell et al.
JOURNAL OF IMMUNOLOGY (2003)
The biology of human natural killer-cell subsets
MA Cooper et al.
TRENDS IN IMMUNOLOGY (2001)
Unique subpopulations of CD56+ NK and NK-T peripheral blood lymphocytes identified by chemokine receptor expression repertoire
JJ Campbell et al.
JOURNAL OF IMMUNOLOGY (2001)
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