期刊
ACS CATALYSIS
卷 10, 期 9, 页码 4983-4989出版社
AMER CHEMICAL SOC
DOI: 10.1021/acscatal.0c01209
关键词
hydrogen atom transfer; radicals; cobalt; photoredox catalysis; hydrofunctionalization
资金
- Natural Science Foundation of China [21901011]
- Thousand Talent Plan Youth Program
- College of Chemistry and Molecular Engineering, Peking University
- BNLMS
A general protocol has been developed for the Markovnikov-selective intermolecular hydrofunctionalization based on visible-light-mediated Co/Ru dual catalysis. The key feature involves the photochemical oxidation of an organocobalt(III) intermediate derived from hydrogen atom transfer, which is supported by electrochemical analysis, quenching studies, and stoichiometric experiments. This redox process enables the efficient branch-selective alkylation of pharmaceutically important nucleophiles (phenols, sulfonamides, and various N-heterocycles) using a wide range of alkenes including moderately electron-deficient ones. Moreover, light-gated polar functionalization via organocobalt species was demonstrated.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据