期刊
NATURE COMMUNICATIONS
卷 11, 期 1, 页码 -出版社
NATURE PORTFOLIO
DOI: 10.1038/s41467-020-16670-2
关键词
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资金
- NMRC Seed Funding Program [TR19NMR119SD]
- NMRC COVID-19 Research Fund [COVID19RF-001, COVID19RF-002]
- NHG-NCID COVID-19 Centre Grant [COVID19CG0002]
- DSO National Laboratories
- NMRC Clinician Scientist Award [MOH-000276]
- NMRC CS-IRG [CIRG18Nov-0034]
- NMRC Research Training Fellowship [NMRC/Fellowship/0056/2018]
Understanding the particle size distribution in the air and patterns of environmental contamination of SARS-CoV-2 is essential for infection prevention policies. Here we screen surface and air samples from hospital rooms of COVID-19 patients for SARS-CoV-2 RNA. Environmental sampling is conducted in three airborne infection isolation rooms (AIIRs) in the ICU and 27 AIIRs in the general ward. 245 surface samples are collected. 56.7% of rooms have at least one environmental surface contaminated. High touch surface contamination is shown in ten (66.7%) out of 15 patients in the first week of illness, and three (20%) beyond the first week of illness (p = 0.01, chi(2) test). Air sampling is performed in three of the 27 AIIRs in the general ward, and detects SARS-CoV-2 PCR-positive particles of sizes >4 mu m and 1-4 mu m in two rooms, despite these rooms having 12 air changes per hour. This warrants further study of the airborne transmission potential of SARS-CoV-2.
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