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MOLECULAR AND CELLULAR BIOLOGY (2009)
Extracellular histones are major mediators of death in sepsis
Jun Xu et al.
NATURE MEDICINE (2009)
MicroRNA Fingerprints Identify miR-150 as a Plasma Prognostic Marker in Patients with Sepsis
Catalin Vasilescu et al.
PLOS ONE (2009)
Endotoxin tolerance: new mechanisms, molecules and clinical significance
Subhra K. Biswas et al.
TRENDS IN IMMUNOLOGY (2009)
Loss of extracellular superoxide dismutase leads to acute lung damage in the presence of ambient air - A potential mechanism underlying adult respiratory distress syndrome
Maria Carolina Gongora et al.
AMERICAN JOURNAL OF PATHOLOGY (2008)
Acetylation of mitogen-activated protein kinase phosphatase-1 inhibits Toll-like receptor signaling
Wangsen Cao et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2008)
Acetylation of MKP-1 and the Control of Inflammation
Hongbo Chi et al.
SCIENCE SIGNALING (2008)
Regulatory T cell populations in sepsis and trauma
Fabienne Venet et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2008)
Epigenetic regulation of dendritic cell-derived interleukin-12 facilitates immunosuppression after a severe innate immune response
Haitao Wen et al.
BLOOD (2008)
MiR-150 controls B cell differentiation by targeting the transcription factor c-myb
Changchun Xiao et al.
CELL (2007)
Suppression of lipopolysaccharide- and tumour necrosis factor-α-induced interleukin (IL)-8 expression by glucocorticoids involves changes in IL-8 promoter acetylation
L. G. Tsaprouni et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2007)
The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing
Francesca De Santa et al.
CELL (2007)
Epigenetic silencing of tumor necrosis factor α during endotoxin tolerance
Mohamed El Gazzar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3+ conventional T cells
Udo Baron et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2007)
Apoptosis-induced acetylation of histones is pathogenic in systemic lupus erythematosus
Jurgen W. Dieker et al.
ARTHRITIS AND RHEUMATISM (2007)
Histone deacetylase activities are required for innate immune cell control of Th1 but not Th2 effector cell function
Jennifer L. Brogdon et al.
BLOOD (2007)
Platelet TLR4 activates neutrophil extracellular traps to ensnare bacteria in septic blood
Stephen R. Clark et al.
NATURE MEDICINE (2007)
Apoptosis and caspases regulate death and inflammation in sepsis
Richard S. Hotchkiss et al.
NATURE REVIEWS IMMUNOLOGY (2006)
NF-κB-dependent induction of microRNA miR-146, an inhibitor targeted to signaling proteins of innate immune responses
Konstantin D. Taganov et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Severe sepsis exacerbates cell-mediated immunity in the lung due to an altered dendritic cell cytokine profile
Haitao Wen et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
Bench-to-bedside review: Endotoxin tolerance as a model of leukocyte reprogramming in sepsis
Jean-Marc Cavaillon et al.
CRITICAL CARE (2006)
The effect of age on the development and outcome of adult sepsis
GS Martin et al.
CRITICAL CARE MEDICINE (2006)
In vivo delivery of caspase-8 or Fas siRNA improves the survival of septic mice
DE Wesche-Soldato et al.
BLOOD (2005)
Endotoxin tolerance disrupts chromatin remodeling and NF-κB transactivation at the IL-1β promoter
C Chan et al.
JOURNAL OF IMMUNOLOGY (2005)
Histone deacetylase inhibitors: new drugs for the treatment of inflammatory diseases?
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DRUG DISCOVERY TODAY (2005)
B-lymphocytes, innate immunity, and autoimmunity
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CLINICAL IMMUNOLOGY (2005)
Longitudinal study of cytokine and immune transcription factor mRNA expression in septic shock
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CLINICAL IMMUNOLOGY (2005)
Neutrophil extracellular traps kill bacteria
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SCIENCE (2004)
Potentiation of tumor necrosis factor-induced NF-κB activation by deacetylase inhibitors is associated with a delayed cytoplasmic reappearance of IκBα
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MOLECULAR AND CELLULAR BIOLOGY (2003)
Elevated nucleosome levels in systemic inflammation and sepsis
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CRITICAL CARE MEDICINE (2003)
Marked elevation of human circulating CD4+CD25+ regulatory T cells in sepsis-induced immunoparalysis
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CRITICAL CARE MEDICINE (2003)
Ezh2 controls B cell development through histone H3 methylation and Igh rearrangement
IH Su et al.
NATURE IMMUNOLOGY (2003)
Synergistic activation of human immunodeficiency virus type 1 promoter activity by NF-κB and inhibitors of deacetylases:: Potential perspectives for the development of therapeutic strategies
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JOURNAL OF VIROLOGY (2002)
Dynamic changes in histone H3 Lys 9 methylation occurring at tightly regulated inducible inflammatory genes
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GENES & DEVELOPMENT (2002)
Coincidence of pro- and anti-inflammatory responses in the early phase of severe sepsis:: Longitudinal study of mononuclear histocompatibility leukocyte antigen-DR expression, procalcitonin, C-reactive protein, and changes in T-cell subsets in septic and postoperative patients
K Tschaikowsky et al.
CRITICAL CARE MEDICINE (2002)
The p65 (RelA) subunit of NF-κB interacts with the histone deacetylase (HDAC) corepressors HDAC1 and HDAC2 to negatively regulate gene expression
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MOLECULAR AND CELLULAR BIOLOGY (2001)
Histone deacetylase as a therapeutic target
OH Krämer et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2001)
Normal responses to injury prevent systemic inflammation and can be immunosuppressive
RS Munford et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2001)
Pro- versus anti-inflammatory cytokine profile in patients with severe sepsis: A marker for prognosis and future therapeutic options
CA Gogos et al.
JOURNAL OF INFECTIOUS DISEASES (2000)