相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Histone methyltransferase SETDB1 promotes colorectal cancer proliferation through the STAT1-CCND1/CDK6 axis
Lu Yu et al.
CARCINOGENESIS (2020)
The lncRNA PVT1 regulates nasopharyngeal carcinoma cell proliferation via activating the KAT2A acetyltransferase and stabilizing HIF-1α
Ying Wang et al.
CELL DEATH AND DIFFERENTIATION (2020)
Human colorectal cancer derived-MSCs promote tumor cells escape from senescence via P53/P21 pathway
G. Li et al.
CLINICAL & TRANSLATIONAL ONCOLOGY (2020)
Elevating H3K27me3 level sensitizes colorectal cancer to oxaliplatin
Qi Wang et al.
JOURNAL OF MOLECULAR CELL BIOLOGY (2020)
SETDB1-mediated methylation of Akt promotes its K63-linked ubiquitination and activation leading to tumorigenesis
Guihua Wang et al.
NATURE CELL BIOLOGY (2019)
AKT methylation by SETDB1 promotes AKT kinase activity and oncogenic functions
Jianping Guo et al.
NATURE CELL BIOLOGY (2019)
Amplification of SMYD3 promotes tumorigenicity and intrahepatic metastasis of hepatocellular carcinoma via upregulation of CDK2 and MMP2
Yu Wang et al.
ONCOGENE (2019)
Emerging roles of H3K9me3, SETDB1 and SETDB2 in therapy-induced cellular reprogramming
Joachim Torrano et al.
CLINICAL EPIGENETICS (2019)
Intestinal PPARα Protects Against Colon Carcinogenesis via Regulation of Methyltransferases DNMT1 and PRMT6
Yuhong Luo et al.
GASTROENTEROLOGY (2019)
Histone methyltransferase SETDB1 contributes to melanoma tumorigenesis and serves as a new potential therapeutic target
Elias Orouji et al.
INTERNATIONAL JOURNAL OF CANCER (2019)
4-Nonylphenol-enhanced EZH2 and RNF2 expression, H3K27me3 and H2AK119ub1 marks resulting in silencing of p21CDKN1A in vitro
Krishna Ghosh et al.
EPIGENOMICS (2019)
Intergenerational epigenetic inheritance of cancer susceptibility in mammals
Bluma J Lesch et al.
eLife (2019)
Cockayne syndrome group B deficiency reduces H3K9me3 chromatin remodeler SETDB1 and exacerbates cellular aging
Jong-Hyuk Lee et al.
NUCLEIC ACIDS RESEARCH (2019)
EZH2, JMJD3, and UTX epigenetically regulate hepatic plasticity inducing retro-differentiation and proliferation of liver cells
Natalia Pediconi et al.
CELL DEATH & DISEASE (2019)
Drugs Targeting Epigenetic Modifications and Plausible Therapeutic Strategies Against Colorectal Cancer
Srinivas Patnaik et al.
FRONTIERS IN PHARMACOLOGY (2019)
Long noncoding RNA MAPKAPK5-AS1 promotes colorectal cancer proliferation by partly silencing p21 expression
Hao Ji et al.
CANCER SCIENCE (2019)
Long non-coding RNA MLK7-AS1 promotes proliferation in human colorectal cancer via downregulation of p21 expression
Rui Zhang et al.
MOLECULAR MEDICINE REPORTS (2019)
Clinical epigenetics: seizing opportunities for translation
Maria Berdasco et al.
NATURE REVIEWS GENETICS (2019)
SETDB1 induces epithelial-mesenchymal transition in breast carcinoma by directly binding with Snail promoter
Wenlin Yang et al.
ONCOLOGY REPORTS (2019)
SETDB1 regulates SMAD7 expression for breast cancer metastasis
Tae Young Ryu et al.
BMB REPORTS (2019)
Targeting Epigenetics in Cancer
Richard L. Bennett et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 58 (2018)
Anti-Proliferative Activity of HPOB against Multiple Myeloma Cells via p21 Transcriptional Activation
Linlin Liu et al.
MOLECULES (2018)
CREPT facilitates colorectal cancer growth through inducing Wnt/beta-catenin pathway by enhancing p300-mediated beta-catenin acetylation
Yanquan Zhang et al.
ONCOGENE (2018)
The ASH1-miR-375-YWHAZ Signaling Axis Regulates Tumor Properties in Hepatocellular Carcinoma
Juan-Feng Zhao et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2018)
Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
Freddie Bray et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2018)
TRIB2 functions as novel oncogene in colorectal cancer by blocking cellular senescence through AP4/p21 signaling
Zhenlin Hou et al.
MOLECULAR CANCER (2018)
Mechanisms for the Inhibition of Colon Cancer Cells by Sulforaphane through Epigenetic Modulation of MicroRNA-21 and Human Telomerase Reverse Transcriptase (hTERT) Down-regulation
Samantha L. Martin et al.
CURRENT CANCER DRUG TARGETS (2018)
Repositioning FDA-Approved Drugs in Combination with Epigenetic Drugs to Reprogram Colon Cancer Epigenome
Noel J. -M. Raynal et al.
MOLECULAR CANCER THERAPEUTICS (2017)
Targeting histone methylation for colorectal cancer
Tao Huang et al.
THERAPEUTIC ADVANCES IN GASTROENTEROLOGY (2017)
Emerging role of SETDB1 as a therapeutic target
Archana Venkataramana Karanth et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2017)
Histone Deacetylase Inhibitors as Anticancer Drugs
Tomas Eckschlager et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Long noncoding RNA CRNDE promotes colorectal cancer cell proliferation via epigenetically silencing DUSP5/CDKN1A expression
Jie Ding et al.
CELL DEATH & DISEASE (2017)
Histone Methyltransferase SETDB1 Promotes the Progression of Colorectal Cancer by Inhibiting the Expression of TP53
Keli Chen et al.
JOURNAL OF CANCER (2017)
Long noncoding RNA HOXA-AS2 represses P21 and KLF2 expression transcription by binding with EZH2, LSD1 in colorectal cancer
J. Ding et al.
ONCOGENESIS (2017)
UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival Analyses
Darshan S. Chandrashekar et al.
NEOPLASIA (2017)
Significance of histone methyltransferase SETDB1 expression in colon adenocarcinoma
Yi-Jung Ho et al.
APMIS (2017)
Up-Regulation of Histone Methyltransferase SETDB1 by Multiple Mechanisms in Hepatocellular Carcinoma Promotes Cancer Metastasis
Chun-Ming Wong et al.
HEPATOLOGY (2016)
Chemical and structural modifications of RNAi therapeutics
Sook Hee Ku et al.
ADVANCED DRUG DELIVERY REVIEWS (2016)
Exploiting the Epigenome to Control Cancer-Promoting Gene-Expression Programs
Gerard L. Brien et al.
CANCER CELL (2016)
Demystifying the mechanistic and functional aspects of p21 gene activation with double-stranded RNAs in human cancer cells
Huan-Lei Wu et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2016)
miR-6734 Up-Regulates p21 Gene Expression and Induces Cell Cycle Arrest and Apoptosis in Colon Cancer Cells
Moo Rim Kang et al.
PLOS ONE (2016)
H3K9me3-Dependent Heterochromatin: Barrier to Cell Fate Changes
Justin S. Becker et al.
TRENDS IN GENETICS (2016)
The interplay of histone modifications - writers that read
Tianyi Zhang et al.
EMBO REPORTS (2015)
Methylation of histone H3 lysine 9 occurs during translation
Carlos Rivera et al.
NUCLEIC ACIDS RESEARCH (2015)
Histone methyltransferase SETDB1 regulates liver cancer cell growth through methylation of p53
Qi Fei et al.
NATURE COMMUNICATIONS (2015)
The p53-induced lincRNA-p21 derails somatic cell reprogramming by sustaining H3K9me3 and CpG methylation at pluripotency gene promoters
Xichen Bao et al.
CELL RESEARCH (2015)
Predicting the human epigenome from DNA motifs
John W. Whitaker et al.
NATURE METHODS (2015)
H3K9 Histone Methyltransferase, KMT1E/SETDB1, Cooperates with the SMAD2/3 Pathway to Suppress Lung Cancer Metastasis
Pei-Chun Wu et al.
CANCER RESEARCH (2014)
UniHI 7: an enhanced database for retrieval and interactive analysis of human molecular interaction networks
Ravi Kiran Reddy Kalathur et al.
NUCLEIC ACIDS RESEARCH (2014)
Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis
M. Rodriguez-Paredes et al.
ONCOGENE (2014)
EZH2 Regulates Cofilin Activity and Colon Cancer Cell Migration by Targeting ITGA2 Gene
Angelo Ferraro et al.
PLOS ONE (2014)
MiR-7, Inhibited Indirectly by LincRNA HOTAIR, Directly Inhibits SETDB1 and Reverses the EMT of Breast Cancer Stem Cells by Downregulating the STAT3 Pathway
Hongyi Zhang et al.
STEM CELLS (2014)
Cancer-associated upregulation of histone H3 lysine 9 trimethylation promotes cell motility in vitro and drives tumor formation in vivo
Yuhki Yokoyama et al.
CANCER SCIENCE (2013)
Cancer Epigenetics: From Mechanism to Therapy
Mark A. Dawson et al.
CELL (2012)
Chromatin organization is a major influence on regional mutation rates in human cancer cells
Benjamin Schuster-Boeckler et al.
NATURE (2012)
EZH2-Dependent Suppression of a Cellular Senescence Phenotype in Melanoma Cells by Inhibition of p21/CDKN1A Expression
Tao Fan et al.
MOLECULAR CANCER RESEARCH (2011)
KMT1E Mediated H3K9 Methylation Is Required for the Maintenance of Embryonic Stem Cells by Repressing Trophectoderm Differentiation
Felix Lohmann et al.
STEM CELLS (2010)
The HP1α-CAF1-SetDB1-containing complex provides H3K9me1 for Suv39-mediated K9me3 in pericentric heterochromatin
Alejandra Loyola et al.
EMBO REPORTS (2009)
Chromatin modifications and their function
Tony Kouzarides
CELL (2007)
UniHI:: an entry gate to the human protein interactome
Gautam Chaurasia et al.
NUCLEIC ACIDS RESEARCH (2007)
The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells
Hongwei Li et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Mammalian cyclin-dependent kinases
M Malumbres et al.
TRENDS IN BIOCHEMICAL SCIENCES (2005)
SETDB1: a novel KAP-1-associated histone H3, lysine 9-specific methyltransferase that contributes to HP1-mediated silencing of euchromatic genes by KRAB zinc-finger proteins
DC Schultz et al.
GENES & DEVELOPMENT (2002)