期刊
CHEMISTRY-A EUROPEAN JOURNAL
卷 22, 期 14, 页码 4700-4703出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201505143
关键词
biomimetic synthesis; deer; EPR spectroscopy; ion channels; membrane proteins; structural biology
资金
- European Union [REA 334496]
- EPSRC [EP/M024660/1]
- Wellcome Trust [099149/Z/12/Z]
- Royal Society [RG140723]
- Biotechnology and Biological Sciences Research Council [BB/H017917/1] Funding Source: researchfish
- Engineering and Physical Sciences Research Council [EP/M024660/1] Funding Source: researchfish
- BBSRC [BB/H017917/1] Funding Source: UKRI
- EPSRC [EP/M024660/1] Funding Source: UKRI
Pulse electron paramagnetic resonance (EPR) is gaining increasing importance in structural biology. The PELDOR (pulsed electron-electron double resonance) method allows extracting distance information on the nanometer scale. Here, we demonstrate the efficient extraction of distances from multimeric systems such as membrane-embedded ion channels where data analysis is commonly hindered by multi-spin effects.
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