期刊
VOX SANGUINIS
卷 115, 期 8, 页码 703-711出版社
WILEY
DOI: 10.1111/vox.12917
关键词
apheresis; blood collector; buffy coat; distributions; platelets; whole blood-derived platelet
类别
Background This multi-national study evaluated changes in platelet (PLT) unit distributions at 12 national or regional blood collectors over a 10-year period. Methods Data on the total number of PLT distributions, the collection method, that is apheresis vs whole blood-derived (WBD), the PLT unit characteristics and post-collection modifications were obtained from 12 national or regional blood collectors from 2008 through 2017. Individual WBD PLT units were converted to apheresis equivalent units (i.e. a dose of PLTs) by dividing by 4, the typical pool size; WBD units that were pooled before distribution were counted as a single dose. Results Overall at these 12 blood collectors, the total number of PLTs distributed in 2008 was 1 373 200, which rose by 10 center dot 2% to 1 513 803 in 2017. The Japanese Red Cross, which distributes only apheresis PLTs, had a 13 center dot 4% increase in the number of distributions between the years 2008 and 2017, while the other 11 blood collectors combined demonstrated a 6 center dot 8% increase in distributions between these two years. Between the years 2008 and 2017, the changes in the proportion of apheresis, platelet-rich plasma and buffy coat PLT distributions were -29 center dot 9%, -70 center dot 7% and 80 center dot 0%, respectively. Conclusion The number of PLT distributions increased during the 10-year study period despite prophylactic PLT transfusion thresholds having remained fairly consistent over the last decade. Perhaps this increase is in part driven by increased administration of platelets to patients with massive haemorrhage or an increase in stem cell transplantation. The use of buffy coat PLTs is increasing at these collectors.
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