期刊
TRENDS IN CELL BIOLOGY
卷 30, 期 7, 页码 501-503出版社
CELL PRESS
DOI: 10.1016/j.tcb.2020.04.001
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资金
- National Key R&D Program of China [2016YFA0502204, 2017YFA0504304]
- National Natural Science Foundation of China [81772960]
- Fundamental Research Funds for the Central Universities [2018SCUH0018]
- Sichuan Science and Technology Program [2019JDTD0013]
- 1.3.5 Project for Disciplines of Excellence, West China Hospital, Sichuan University [ZYJC18030]
The elaborate control of biogenesis and turnover is essential for circular RNAs (circRNAs) to exert their functions properly in eukaryotic cells, whereas how circRNAs are degraded remains unclear. A recent study by Fischer et al. reveals a novel structure-mediated circRNA decay that selectively degrades highly structured RNAs by UPF1 and G3BP1.
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