期刊
SLEEP AND BREATHING
卷 25, 期 1, 页码 263-270出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s11325-020-02110-4
关键词
PVT; Sleep-disordered breathing; Arousal duration; OSA; Electroencephalogram
资金
- Seinajoki Central Hospital
- Competitive State Research Financing of Expert Responsibility Area of Tampere University Hospital [VTR3221, VTR3228, EVO2089]
- Tampere Tuberculosis Foundation
This study examined whether changing the minimum EEG arousal duration could improve the association between sleep fragmentation and neurocognitive outcomes in patients with obstructive sleep apnoea. The findings suggest that a re-examination of EEG arousal scoring rules and duration could help allocate health resources more effectively to OSA patients in need.
Purpose Obstructive sleep apnoea (OSA) is a prevalent sleep disorder with significant health consequences. Sleep fragmentation is a feature of OSA and is often determined by the arousal index (ArI), a metric based on the electroencephalograph (EEG). The ArI has a weak correlation with neurocognitive outcomes in OSA patients. In this study, we examine whether changing from the current minimum EEG arousal duration of 3 s improves the association between sleep fragmentation and neurocognitive outcomes. Methods In a retrospective study, we selected OSA patients without any other comorbidities that are associated with neurocognitive impairment. The OSA patients were clustered into two groups based on their psychomotor vigilance task (PVT) performance to represent impaired and unimpaired neurocognition. Results While no differences were found in demographics or usual sleep study statistics, the impaired group had a greater number of EEG arousals greater than 5 s (P = 0.034), 7 s (P = 0.041), and 15 s (P = 0.036) in duration. There were no differences in the number of EEG arousals associated with sleep-disordered breathing events. These differences also corresponded with quality of life outcomes between the two groups. An ArI with a duration of 5 s or greater had the best combination of sensitivity (70.0%) and specificity (66.7%) compared with the usual 3 s duration (sensitivity and specificity of 70.0% and 53.3%, respectively). Conclusion A re-examination of the EEG arousal scoring rules, and their duration, may help with allocation of health resources to OSA patients most in need.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据