期刊
SCIENCE
卷 367, 期 6483, 页码 1246-+出版社
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.aba1120
关键词
-
资金
- Royal Society [UF130004]
- EPSRC [EP/N005422/1]
- European Research Council under the Horizon 2020 Program [757381]
- AstraZeneca
- Emil Aaltonen Foundation
- EPSR
- Syngenta
- Royal Society [UF130004] Funding Source: Royal Society
- EPSRC [EP/N005422/1, 1943646, 1918558] Funding Source: UKRI
Chiral cations have been used extensively as organocatalysts, but their application to rendering transition metal-catalyzed processes enantioselective remains rare. This is despite the success of the analogous charge-inverted strategy in which cationic metal complexes are paired with chiral anions. We report here a strategy to render a common bipyridine ligand anionic and pair its iridium complexes with a chiral cation derived from quinine. We have applied these ion-paired complexes to long-range asymmetric induction in the desymmetrization of the geminal diaryl motif, located on a carbon or phosphorus center, by enantioselective C-H borylation. In principle, numerous common classes of ligand could likewise be amenable to this approach.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据