期刊
RECORDS OF NATURAL PRODUCTS
卷 14, 期 4, 页码 307-311出版社
ACG PUBLICATIONS
DOI: 10.25135/rnp.162.19.11.1487
关键词
Aspergillus sp.; aspertriols A-B; isolation; identification
资金
- National Key R&D Program of China [2017YFD0600702-2]
- China Ocean Mineral Resources R&D Association (COMRA) Program [DY135-B2-01]
- China Postdoctoral Science Foundation [2018M630815]
- First-Class Discipline Construction Project of Henan University [2018YLZDCG03]
Chemical examination of a fraction of the EtOAc extract of a marine-derived fungus Aspergillus sp. YPGA8 resulted in the isolation of two new compounds, namely aspertriols A-B (1-2). Compounds 1-2 possess an identical 2,3,4-trihydroxybutoxy moiety, which is rarely found in natural products. Their structures were determined by extensive analyses of spectroscopic data (1D and 2D NMR, HRESIMS). The bioassay study revealed that compounds 1 and 2 were inactive toward alpha-glucosidase.
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