期刊
PROGRESS IN RETINAL AND EYE RESEARCH
卷 79, 期 -, 页码 -出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.preteyeres.2020.100865
关键词
Central serous chorioretinopathy (CSC); Choroid; Retinal pigment epithelium (RPE); Corticosteroids; Choroidal endothelial cells (CECs); Complement factor H (CFH); Pachychoroid; Hyperpermeability; Mineralocorticoids; Eplerenone
资金
- NIHR Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust
- UCL Institute of Ophthalmology
- NIHR
- GCRF UKRI [MR/P207881/1]
Central serous chorioretinopathy (CSC) is a common form of vision loss, typically seen in working-age men. The pathophysiology behind CSC still eludes us, however significant advances have been made in understanding this disease over the last decade using information from genetic and cell-based studies and imaging modalities. This review aims to give an overview of the current pathophysiology hypotheses surrounding CSC in addition to future directions in cellular work from human induced pluripotent stem cell derived choroidal endothelial cells from CSC patients. Furthermore, this review will provide the reader with an update on the clinical aspects of CSC including risk factors, diagnostic challenges and findings from multimodal imaging.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据