期刊
PLANT BIOLOGY
卷 22, 期 6, 页码 971-980出版社
WILEY
DOI: 10.1111/plb.13114
关键词
Chromosome defects; microtubule; microtubule nucleation; microtubule-associated proteins; spindle microtubule defects; UV-B radiation
资金
- 2018 Graduate Science and Technology Innovation of Shanxi Normal University [01053012]
- 2019 Innovation Project of Postgraduate Education of Shanxi Province [2019BY090]
Microtubules (MT) are critical cytoskeletal filaments that have several functions in cell morphogenesis, cell division, vesicle transport and cytoplasmic separation in the spatiotemporal regulation of eukaryotic cells. Formation of MT requires the co-interaction of MT nucleation and alpha-beta-tubulins, as well as MT-associated proteins (MAP). Many key MAP contributing to MT nucleation and elongation are essential for MT nucleation and regulation of MT dynamics, and are conserved in the plant kingdom. Therefore, the deletion or decrease of gamma-tubulin ring complex (gamma TuRC) components and related MAP, such as the augmin complex, NEDD1, MZT1, EB1, MAP65, etc., inArabidopsis thalianaresults in MT organizational defects in the spindle and phragmoplast MT, as well as in chromosome defects. In addition, similar defects in MT organization and chromosome structure have been observed in plants under abiotic stress conditions, such as under high UV-B radiation. The MT can sense the signal from UV-B radiation, resulting in abnormal MT arrangement. Further studies are required to determine whether the abnormal chromosomes induced by UV-B radiation can be attributed to the involvement of abnormal MT arrays in chromosome migration after DNA damage.
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