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DIABETES (2008)
Metabolic adaptations through the PGC-1α and SIRT1 pathways
Joseph T. Rodgers et al.
FEBS LETTERS (2008)
mTOR controls mitochondrial oxidative function through a YY1-PGC-1α transcriptional complex
John T. Cunningham et al.
NATURE (2007)
Abnormal glucose homeostasis in skeletal muscle-specific PGC-1α knockout mice reveals skeletal muscle-pancreatic β cell crosstalk
Christoph Handschin et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Hepatic lipin 1β expression is diminished in insulin-resistant obese subjects and is reactivated by marked weight loss
Michelle A. Croce et al.
DIABETES (2007)
Adipose mitochondrial biogenesis is suppressed in db/db and high-fat diet-fed mice and improved by rosiglitazone
James X. Rong et al.
DIABETES (2007)
Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1α transcription coactivator
Xinghai Li et al.
NATURE (2007)
Effects of PGC-1α at on TNF-α-induced MCP-1 and VCAM-1 expression and NF-κB activation in human aortic smooth muscle and endothelial cells
Hye-Jin Kim et al.
ANTIOXIDANTS & REDOX SIGNALING (2007)
Insulin resistance accelerates a dietary rat model of nonalcoholic steatohepatitis
Tsuguhito Ota et al.
GASTROENTEROLOGY (2007)
PGC-1α:: a key regulator of energy metabolism
Huiyun Liang et al.
ADVANCES IN PHYSIOLOGY EDUCATION (2006)
Resveratrol improves health and survival of mice on a high-calorie diet
Joseph A. Baur et al.
NATURE (2006)
Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators
Julie St-Pierre et al.
CELL (2006)
Transverse aortic constriction leads to accelerated heart failure in mice lacking PPAR-γ coactivator 1α
Zoltan Arany et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Evidence for a mitochondrial regulatory pathway defined by peroxisome proliferator-activated receptor-γ coactivator-1α, estrogen-related receptor-α, and mitofusin 2
Francesc X. Soriano et al.
DIABETES (2006)
GCN5 acetyltransferase complex controls glucose metabolism through transcriptional repression of PGC-1α
Caries Lerin et al.
CELL METABOLISM (2006)
Mitochondria are impaired in the adipocytes of type 2 diabetic mice
HJ Choo et al.
DIABETOLOGIA (2006)
p38 mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis
WH Cao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Neuronal nitric oxide synthase controls enzyme activity pattern of mitochondria and lipid metabolism
L Schild et al.
FASEB JOURNAL (2005)
Suppression of estrogen-related receptor α and medium-chain acyl-coenzyme A dehydrogenase in the acute-phase response
MS Kim et al.
JOURNAL OF LIPID RESEARCH (2005)
Atorvastatin prevents peroxisome proliferator-activated receptor γ coactivator-1 (PGC-1) downregulation in lipopolysaccharide-stimulated H9c2 cells
A Planavila et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2005)
PGC-1α regulates the mitochondrial antioxidant defense system in vascular endothelial cells
I Valle et al.
CARDIOVASCULAR RESEARCH (2005)
Metabolic control through the PGC-1 family of transcription coactivators
JD Lin et al.
CELL METABOLISM (2005)
PGC-1α deficiency causes multi-system energy metabolic derangements:: Muscle dysfunction, abnormal weight control and hepatic steatosis
TC Leone et al.
PLOS BIOLOGY (2005)
Transcriptional coactivator PGC-1α controls the energy state and contractile function of cardiac muscle
Z Arany et al.
CELL METABOLISM (2005)
Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1
JT Rodgers et al.
NATURE (2005)
PGC-1 promotes insulin resistance in liver through PPAR-α-dependent induction of TRB-3
SH Koo et al.
NATURE MEDICINE (2004)
p38 mitogen-activated protein kinase is the central regulator of cyclic AMP-dependent transcription of the brown fat uncoupling protein 1 gene
WH Cao et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1α:: modulation by p38 MAPK
M Fan et al.
GENES & DEVELOPMENT (2004)
Altered expression of nuclear hormone receptors and coactivators in mouse heart during the acute-phase response
K Feingold et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2004)
Real-time imaging of peroxisome proliferator-activated receptor-γ coactivator-1α promoter activity in skeletal muscles of living mice
T Akimoto et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2004)
Vanin-1-/- mice exhibit a glutathione-mediated tissue resistance to oxidative stress
C Berruyer et al.
MOLECULAR AND CELLULAR BIOLOGY (2004)
Histone demethylation mediated by the nuclear arnine oxidase homolog LSD1
YJ Shi et al.
CELL (2004)
The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector
RA Screaton et al.
CELL (2004)
Defects in adaptive energy metabolism with CNS-Linked hyperactivity in PGC-1α null mice
JD Lin et al.
CELL (2004)
Role of calcium and AMP kinase in the regulation of mitochondrial biogenesis and GLUT4 levels in muscle
EO Ojuka
PROCEEDINGS OF THE NUTRITION SOCIETY (2004)
An autoregulatory loop controls peroxisome proliferator-activated receptor γ coactivator 1α expression in muscle
C Handschin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism -: A novel regulatory mechanism altered in obesity
D Bach et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Regulation of PGG1 promoter activity by protein kinase B and the forkhead transcription factor FKHR
H Daitoku et al.
DIABETES (2003)
Peroxisome proliferator-activated receptor-γ coactivator 1α (PGC-1α):: Transcriptional coactivator and metabolic regulator
P Puigserver et al.
ENDOCRINE REVIEWS (2003)
Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1
K Baar et al.
FASEB JOURNAL (2002)
In situ detection of lipid peroxidation and oxidative DNA damage in non-alcoholic fatty liver diseases
S Seki et al.
JOURNAL OF HEPATOLOGY (2002)
The PGC-1-related protein PERC is a selective coactivator of estrogen receptor α
D Kressler et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Regulation of mitochondrial biogenesis in skeletal muscle by CaMK
H Wu et al.
SCIENCE (2002)
Peroxisome proliferator-activated receptor γ coactivator 1β (PGC-1β), a novel PGC-1-related transcription coactivator associated with host cell factor
JD Lin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Cytokine stimulation of energy expenditure through p38 MAP kinase activation of PPARγ coactivator-1
P Puigserver et al.
MOLECULAR CELL (2001)
Role of AMP-activated protein kinase in mechanism of metformin action
GC Zhou et al.
JOURNAL OF CLINICAL INVESTIGATION (2001)
CREB regulates hepatic gluconeogenesis through the coactivator PGC-1
S Herzig et al.
NATURE (2001)
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
JC Yoon et al.
NATURE (2001)
Regulation of the transcriptional coactivator PGC-1 via MAPK-sensitive interaction with a repressor
D Knutti et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Impact of endotoxin on UCP homolog mRNA abundance, thermoregulation, and mitochondrial proton leak kinetics
XX Yu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2000)
CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis
IA Leclercq et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)
A tissue-specific coactivator of steroid receptors, identified in a functional genetic screen
D Knutti et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
The coactivator PGC-1 cooperates with peroxisome proliferator-activated receptor alpha in transcriptional control of nuclear genes encoding mitochondrial fatty acid oxidation enzymes
RB Vega et al.
MOLECULAR AND CELLULAR BIOLOGY (2000)
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