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Enantioselective syntheses of indanes: from organocatalysis to C-H functionalization

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CHEMICAL SOCIETY REVIEWS
卷 45, 期 5, 页码 1368-1386

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c5cs00622h

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The indanyl core is ubiquitous in a large variety of drugs and natural products. Importantly, the ever-increasing demand for chiral catalysts bearing this scaffold calls for state of the art methods allowing for a step-economical enantioselective access to this structural motif. We herein summarize the asymmetric syntheses of indanes with a particular focus on asymmetric catalysis, covering the literature of the last decade until July 2015.

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