期刊
ORGANIC LETTERS
卷 22, 期 11, 页码 4097-4102出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.0c01159
关键词
-
资金
- National Natural Science Foundation of China [21901184, 21572160, 21702091]
- Doctoral Program Foundation of Tianjin Normal University [043135202-XB1703]
- Program for Innovative Research Team in University of Tianjin [TD13-5074]
- Science&Technology Development Fund of Tianjin Education Commission for Higher Education [:2018KJ159]
Here we report a protocol to synthesize diversiform fluorinated isocryptolepine analogues with potential biological activities in one step via directed C-2 and C-3 dual C-H functionalization of indoles. We also attempted to take into account fluorinated imidoyl chlorides as a novel kind of synthons in the directed C-H functionalization reactions. As a result, a variety of fluorinated isocryptolepine analogues were obtained in up to 96% yield. Moreover, we conducted control experiments to disclose the reaction mechanism.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据