期刊
ORGANIC LETTERS
卷 22, 期 11, 页码 4327-4332出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.0c01363
关键词
-
资金
- National Natural Science Foundation of China [21625206, 21632009, 21421002]
- Strategic Priority Research Program of the Chinese Academy of Sciences [XDB20000000]
A cobalt-catalyzed asymmetric cross-coupling of alpha-bromo-alpha-fluorotoluene derivatives with a variety of aryl zincates derived from lithium aryl n-butyl pinacol boronates and ZnBr2 under mild reaction conditions was described. In addition to mild reaction conditions, another advantage includes the compatibility of various common functional groups such as fluoride, chloride, bromide, cyano, or ester groups. Furthermore, this protocol was successfully applied to the enantioselective synthesis of three fluorinated derivatives of biologically active compounds or drug molecules.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据