期刊
ORGANIC LETTERS
卷 22, 期 9, 页码 3717-3721出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.0c01213
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资金
- Advantage West Midlands (AWM)
- European Regional Development Fund (ERDF)
A systematic range of o-hydroxyphenyl ketones were reduced under asymmetric transfer hydrogenation conditions using the C3-tethered catalyst 2. Two directing effects, i.e., an o-hydroxyphenyl coupled to a bulky aromatic on the opposite side of the ketone substrate, combine in a matched manner to deliver reduction products with very high enantiomeric excess.
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