期刊
OPTICS LETTERS
卷 45, 期 11, 页码 2973-2976出版社
OPTICAL SOC AMER
DOI: 10.1364/OL.390920
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- [FS 13520230]
Advances in human brain imaging technologies are critical to understanding how the brain works and the diagnosis of brain disorders. Existing technologies have different drawbacks, and the human skull poses a great challenge for pure optical and ultrasound imaging technologies. Here we demonstrate the feasibility of using ultrasound-modulated optical tomography, a hybrid technology that combines both light and sound, to image through human skulls. Single-shot off-axis holography was used to measure the field of the ultrasonically tagged light. This Letter paves the way for imaging the brain noninvasively through the skull, with optical contrast and a higher spatial resolution than that of diffuse optical tomography. (C) 2020 Optical Society of America
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