期刊
CHEMICAL REVIEWS
卷 116, 期 4, 页码 2478-2601出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.chemrev.5b00484
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资金
- European Research Council under the project FOLDHALO [ERC-2012-StG_20111012, 307108]
- Academy of Finland [276537]
- Academy of Finland (AKA) [276537, 276537] Funding Source: Academy of Finland (AKA)
The halogen bond occurs when there is evidence of a net attractive interaction between an electrophilic region associated with a halogen atom in a molecular entity and a nucleophilic region in another, or the same, molecular entity. In this fairly extensive review, after a brief history of the interaction, we will provide the reader with a snapshot of where the research on the halogen bond is now, and, perhaps, where it is going. The specific advantages brought up by a design based on the use of the halogen bond will be demonstrated in quite different fields spanning from material sciences to biomolecular recognition and drug design.
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