期刊
NUTRITION IN CLINICAL PRACTICE
卷 35, 期 3, 页码 386-405出版社
WILEY
DOI: 10.1002/ncp.10490
关键词
asthma; developmental disabilities; gastrointestinal microbiome; human milk; infant formula; microbiota; obesity; pediatrics; prebiotics
资金
- National Institute on Alcohol Abuse and Alcoholism [R00AA023266]
The early-life microbiome is gaining appreciation as a major influencer in human development and long-term health. Multiple factors are known to influence the initial colonization, development, and function of the neonatal gut microbiome. In addition, alterations in early-life gut microbial composition is associated with several chronic health conditions such as obesity, asthma, and allergies. In this review, we focus on both maternal and infant factors known to influence early-life gut colonization. Also reviewed is the important role of infant feeding, including evidence-based strategies for maternal and infant supplementation with the goal to protect and/or restore the infant gut microbiome.
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