期刊
NEUROSURGERY CLINICS OF NORTH AMERICA
卷 31, 期 2, 页码 167-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.nec.2019.12.001
关键词
Stereotactic spine radiosurgery; Hypofractionated stereotactic body radiation therapy; Treatment planning; Reirradiation of spine metastases; Spine radiosurgery dose constraints; Spine SBRT
When treating solid tumor spine metastases, stereotactic high-dose-per-fraction radiation, given in a single fraction or in a hypofractionated approach, has proved to be a highly effective and safe therapeutic option for any tumor histology, in the setting of de novo therapy, as salvage treatment of local progression after previous radiation, and in the postoperative setting. There are variations in practice based on the clinical presentation, goals of therapy, as well as institutional preferences. As a biologically potent therapy, a thoughtful and careful attention to detail with patient selection, treatment planning, and delivery is crucial for treatment success.
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