4.5 Review

Genomic heterogeneity in bladder cancer: challenges and possible solutions to improve outcomes

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Oncology

Mutational landscape of non-muscle-invasive bladder cancer

Carolyn D. Hurst et al.

Summary: Non-muscle-invasive bladder cancer (NMIBC) includes different stages and pathological types of tumors, which are associated with diverse clinical outcomes. Accumulated molecular information on NMIBC provides insights into improved disease management in the future.

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS (2022)

Article Oncology

Molecular tumor heterogeneity in muscle invasive bladder cancer: Biomarkers, subtypes, and implications for therapy

Jose Batista da Costa et al.

Summary: This review discusses the inter- and intratumor heterogeneity in muscle invasive bladder cancer (MIBC) and explores the clinical implications of this heterogeneity for biomarker-driven strategies and the development of new therapies. Molecular subtyping and genomic alterations may help explain variations in treatment response among patients.

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS (2022)

Article Urology & Nephrology

A Consensus Molecular Classification of Muscle-invasive Bladder Cancer

Aurelie Kamoun et al.

EUROPEAN UROLOGY (2020)

Article Urology & Nephrology

Intratumoral Heterogeneity of Bladder Cancer by Molecular Subtypes and Histologic Variants

Joshua I. Warrick et al.

EUROPEAN UROLOGY (2019)

Article Oncology

Molecular Characterization of Neuroendocrine-like Bladder Cancer

Jose Batista da Costa et al.

CLINICAL CANCER RESEARCH (2019)

Article Medicine, General & Internal

Erdafitinib in Locally Advanced or Metastatic Urothelial Carcinoma

Y. Loriot et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

Article Oncology

Role of rebiopsy in metastatic breast cancer at progression

Manish Sharma et al.

CURRENT PROBLEMS IN CANCER (2019)

Review Cell Biology

Variants and new entities of bladder cancer

Antonio Lopez-Beltran et al.

HISTOPATHOLOGY (2019)

Review Urology & Nephrology

Immunotherapy in metastatic urothelial carcinoma: focus on immune checkpoint inhibition

Arlene Siefker-Radtke et al.

NATURE REVIEWS UROLOGY (2018)

Article Oncology

Pathogenic and targetable genetic alterations in 70 urachal adenocarcinomas

Henning Reis et al.

INTERNATIONAL JOURNAL OF CANCER (2018)

Review Oncology

Precision medicine and bladder cancer heterogeneity

Guofeng Ma et al.

BULLETIN DU CANCER (2018)

Review Urology & Nephrology

Biology of nonmuscle-invasive bladder cancer: pathology, genomic implications, and immunology

Lars Dyrskjot et al.

CURRENT OPINION IN UROLOGY (2018)

Article Multidisciplinary Sciences

TGFβ attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells

Sanjeev Mariathasan et al.

NATURE (2018)

Article Biochemistry & Molecular Biology

A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade

Livnat Jerby-Arnon et al.

Article Multidisciplinary Sciences

Lineage tracking reveals dynamic relationships of T cells in colorectal cancer

Lei Zhang et al.

NATURE (2018)

Article Oncology

Therapy resistance mediated by cancer stem cells

Teresa Bernadette Steinbichler et al.

SEMINARS IN CANCER BIOLOGY (2018)

Review Medicine, General & Internal

Liquid Biopsy in Clinical Management of Breast, Lung, and Colorectal Cancer

Ivana Bratic Hench et al.

FRONTIERS IN MEDICINE (2018)

Article Urology & Nephrology

EAU Guidelines on Non-Muscle-invasive Urothelial Carcinoma of the Bladder: Update 2016

Marko Babjuk et al.

EUROPEAN UROLOGY (2017)

Review Genetics & Heredity

Mechanisms and clinical implications of tumor heterogeneity and convergence on recurrent phenotypes

Jasmine A. McQuerry et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2017)

Article Medicine, General & Internal

Tracking the Evolution of Non-Small-Cell Lung Cancer

M. Jamal-Hanjani et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Article Medicine, Research & Experimental

Principles of Reconstructing the Subclonal Architecture of Cancers

Stefan C. Dentro et al.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2017)

Article Genetics & Heredity

Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden

Zachary R. Chalmers et al.

GENOME MEDICINE (2017)

Article Oncology

Genomic Activation of PPARG Reveals a Candidate Therapeutic Axis in Bladder Cancer

Jonathan T. Goldstein et al.

CANCER RESEARCH (2017)

Article Biochemistry & Molecular Biology

Tumor and Microenvironment Evolution during Immunotherapy with Nivolumab

Nadeem Riaz et al.

Article Oncology

Circulating Tumor DNA Reveals Clinically Actionable Somatic Genome of Metastatic Bladder Cancer

Gillian Vandekerkhove et al.

CLINICAL CANCER RESEARCH (2017)

Article Biochemistry & Molecular Biology

Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer

A. Gordon Robertson et al.

Review Medical Laboratory Technology

Using circulating cell-free DNA to monitor personalized cancer therapy

Michael Oellerich et al.

CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES (2017)

Review Biochemistry & Molecular Biology

Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future

Nicholas McGranahan et al.

Article Urology & Nephrology

Gene Expression Profile of the Clinically Aggressive Micropapillary Variant of Bladder Cancer

Charles Chuanhai Guo et al.

EUROPEAN UROLOGY (2016)

Article Biochemistry & Molecular Biology

APOBEC-induced mutations in human cancers are strongly enriched on the lagging DNA strand during replication

Vladimir B. Seplyarskiy et al.

GENOME RESEARCH (2016)

Review Medicine, General & Internal

Bladder cancer

Ashish M. Kamat et al.

LANCET (2016)

Article Oncology

Spatial and temporal clonal evolution during development of metastatic urothelial carcinoma

Mathilde B. H. Thomsen et al.

MOLECULAR ONCOLOGY (2016)

Article Genetics & Heredity

Frequent somatic CDH1 loss-of-function mutations in plasmacytoid variant bladder cancer

Hikmat A. Al-Ahmadie et al.

NATURE GENETICS (2016)

Article Genetics & Heredity

Clonal evolution of chemotherapy-resistant urothelial carcinoma

Bishoy M. Faltas et al.

NATURE GENETICS (2016)

Article Biochemistry & Molecular Biology

Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer

Himisha Beltran et al.

NATURE MEDICINE (2016)

Review Biochemistry & Molecular Biology

The APOBEC Protein Family: United by Structure, Divergent in Function

Jason D. Salter et al.

TRENDS IN BIOCHEMICAL SCIENCES (2016)

Article Multidisciplinary Sciences

Differential clonal evolution in oesophageal cancers in response to neo-adjuvant chemotherapy

John M. Findlay et al.

NATURE COMMUNICATIONS (2016)

Meeting Abstract Oncology

Assessment of genomic alterations in bladder adenocarcinoma and urachal adenocarcinoma

E. Jordan et al.

EUROPEAN JOURNAL OF CANCER (2015)

Article Multidisciplinary Sciences

Comprehensive genomic profiles of small cell lung cancer

Julie George et al.

NATURE (2015)

Article Multidisciplinary Sciences

A spatial model predicts that dispersal and cell turnover limit intratumour heterogeneity

Bartlomiej Waclaw et al.

NATURE (2015)

Review Oncology

APOBEC Enzymes: Mutagenic Fuel for Cancer Evolution and Heterogeneity

Charles Swanton et al.

CANCER DISCOVERY (2015)

Article Pathology

Distinguishing Nested Variants of Urothelial Carcinoma From Benign Mimickers by TERT Promoter Mutation

Minghao Zhong et al.

AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2014)

Meeting Abstract Oncology

Branched evolution and intratumor heterogeneity of urothelial carcinoma of the bladder.

Eugene K. Cha et al.

JOURNAL OF CLINICAL ONCOLOGY (2014)

Article Multidisciplinary Sciences

Comprehensive molecular characterization of urothelial bladder carcinoma

John N. Weinstein et al.

NATURE (2014)

Review Microbiology

AID and APOBECs span the gap between innate and adaptive immunity

Arnaud Moris et al.

FRONTIERS IN MICROBIOLOGY (2014)

Article Biotechnology & Applied Microbiology

Unraveling the clonal hierarchy of somatic genomic aberrations

Davide Prandi et al.

GENOME BIOLOGY (2014)

Article Medical Laboratory Technology

High-Risk Human Papillomavirus DNA Detected in Primary Squamous Cell Carcinoma of Urinary Bladder

Jennifer Rose Chapman-Fredricks et al.

ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE (2013)

Article Genetics & Heredity

Evidence for APOBEC3B mutagenesis in multiple human cancers

Michael B. Burns et al.

NATURE GENETICS (2013)

Article Genetics & Heredity

An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers

Steven A. Roberts et al.

NATURE GENETICS (2013)

Article Oncology

A Molecular Taxonomy for Urothelial Carcinoma

Gottfrid Sjodahl et al.

CLINICAL CANCER RESEARCH (2012)

Review Medicine, Research & Experimental

Role of intratumoural heterogeneity in cancer drug resistance: molecular and clinical perspectives

Nicholas A. Saunders et al.

EMBO MOLECULAR MEDICINE (2012)

Review Multidisciplinary Sciences

Clonal evolution in cancer

Mel Greaves et al.

NATURE (2012)

Article Medicine, General & Internal

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

Marco Gerlinger et al.

NEW ENGLAND JOURNAL OF MEDICINE (2012)

Review Cell Biology

Functions and regulation of the APOBEC family of proteins

Harold C. Smith et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2012)

Review Oncology

Circumventing Cancer Drug Resistance in the Era of Personalized Medicine

Levi A. Garraway et al.

CANCER DISCOVERY (2012)

Article Oncology

The plasmacytoid carcinoma of the bladder-rare variant of aggressive urothelial carcinoma

Bastian Keck et al.

INTERNATIONAL JOURNAL OF CANCER (2011)

Article Multidisciplinary Sciences

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

Shinichi Yachida et al.

NATURE (2010)

Article Pathology

Urachal Carcinoma A Clinicopathologic Analysis of 24 Cases With Outcome Correlation

Anuradha Gopalan et al.

AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2009)

Article Multidisciplinary Sciences

APOBEC3 inhibits mouse mammary tumour virus replication in vivo

Chioma M. Okeoma et al.

NATURE (2007)

Article Oncology

A molecular signature in superficial bladder carcinoma predicts clinical outcome

L Dyrskjot et al.

CLINICAL CANCER RESEARCH (2005)

Article Medicine, General & Internal

Neoadjuvant chemotherapy plus cystectomy compared with cystectomy alone for locally advanced bladder cancer

HB Grossman et al.

NEW ENGLAND JOURNAL OF MEDICINE (2003)