4.8 Article

Copper is an essential regulator of the autophagic kinases ULK1/2 to drive lung adenocarcinoma

相关参考文献

注意:仅列出部分参考文献,下载原文获取全部文献信息。
Article Biochemistry & Molecular Biology

Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer

Kirsten L. Bryant et al.

NATURE MEDICINE (2019)

Article Biochemistry & Molecular Biology

Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers

Conan G. Kinsey et al.

NATURE MEDICINE (2019)

Article Multidisciplinary Sciences

MAP kinase and autophagy pathways cooperate to maintain RAS mutant cancer cell survival

Chih-Shia Lee et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)

Article Multidisciplinary Sciences

RB constrains lineage fidelity and multiple stages of tumour progression and metastasis

David M. Walter et al.

NATURE (2019)

Review Oncology

Targeting Autophagy in Cancer: Recent Advances and Future Directions

Ravi K. Amaravadi et al.

CANCER DISCOVERY (2019)

Review Biochemistry & Molecular Biology

A molecular perspective of mammalian autophagosome biogenesis

Thomas J. Mercer et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2018)

Article Biochemistry & Molecular Biology

Copper regulates rest-activity cycles through the locus coeruleus-norepinephrine system

Tong Xiao et al.

NATURE CHEMICAL BIOLOGY (2018)

Article Biochemistry & Molecular Biology

Copper regulates cyclic-AMP-dependent lipolysis

Lakshmi Krishnamoorthy et al.

Nature Chemical Biology (2016)

Article Biochemistry & Molecular Biology

Pharmacological Inhibition of ULK1 Kinase Blocks Mammalian Target of Rapamycin (mTOR)-dependent Autophagy

Katy J. Petherick et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2015)

Article Biochemistry & Molecular Biology

Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates

Daniel F. Egan et al.

MOLECULAR CELL (2015)

Article Gastroenterology & Hepatology

Hepatobiliary malignancies in Wilson disease

Jan Pfeiffenberger et al.

LIVER INTERNATIONAL (2015)

Review Oncology

The dynamic control of signal transduction networks in cancer cells

Walter Kolch et al.

NATURE REVIEWS CANCER (2015)

Article Multidisciplinary Sciences

Comprehensive molecular profiling of lung adenocarcinoma

Eric A. Collisson et al.

NATURE (2014)

Article Multidisciplinary Sciences

Copper is required for oncogenic BRAF signalling and tumorigenesis

Donita C. Brady et al.

NATURE (2014)

Letter Biochemical Research Methods

Improved vectors and genome-wide libraries for CRISPR screening

Neville E. Sanjana et al.

NATURE METHODS (2014)

Article Cell Biology

Dynamic association of the ULK1 complex with omegasomes during autophagy induction

Eleftherios Karanasios et al.

JOURNAL OF CELL SCIENCE (2013)

Article Cell Biology

ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase

Ryan C. Russell et al.

NATURE CELL BIOLOGY (2013)

Article Biochemistry & Molecular Biology

A Novel Role for Copper in Ras/Mitogen-Activated Protein Kinase Signaling

Michelle L. Turski et al.

MOLECULAR AND CELLULAR BIOLOGY (2012)

Article Multidisciplinary Sciences

A unifying model for mTORC1-mediated regulation of mRNA translation

Carson C. Thoreen et al.

NATURE (2012)

Editorial Material Biochemistry & Molecular Biology

Copper: An essential metal in biology

Richard A. Festa et al.

CURRENT BIOLOGY (2011)

Article Cell Biology

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Joungmok Kim et al.

NATURE CELL BIOLOGY (2011)

Article Cell Biology

A novel quantitative flow cytometry-based assay for autophagy

Kai Er Eng et al.

AUTOPHAGY (2010)

Article Biochemistry & Molecular Biology

mTOR Ser-2481 Autophosphorylation Monitors mTORC-specific Catalytic Activity and Clarifies Rapamycin Mechanism of Action

Ghada A. Soliman et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Biochemistry & Molecular Biology

Regulation of the Copper Chaperone CCS by XIAP-Mediated Ubiquitination

Graham F. Brady et al.

MOLECULAR AND CELLULAR BIOLOGY (2010)

Article Biochemistry & Molecular Biology

PLIC proteins or ubiquilins regulate autophagy-dependent cell survival during nutrient starvation

Elsa-Noah N'Diaye et al.

EMBO REPORTS (2009)

Article Biochemistry & Molecular Biology

ULK1•ATG13•FIP200 Complex Mediates mTOR Signaling and Is Essential for Autophagy

Ian G. Ganley et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Article Cell Biology

Nutrient-dependent mTORC1 Association with the ULK1-Atg13-FIP200 Complex Required for Autophagy

Nao Hosokawa et al.

MOLECULAR BIOLOGY OF THE CELL (2009)

Article Cell Biology

ULK-Atg13-FIP200 Complexes Mediate mTOR Signaling to the Autophagy Machinery

Chang Hwa Jung et al.

MOLECULAR BIOLOGY OF THE CELL (2009)

Article Cell Biology

Induction of autophagy during extracellular matrix detachment promotes cell survival

Christopher Fung et al.

MOLECULAR BIOLOGY OF THE CELL (2008)

Article Biochemistry & Molecular Biology

AMPK phosphorylation of raptor mediates a metabolic checkpoint

Dana M. Gwinn et al.

MOLECULAR CELL (2008)

Article Cell Biology

Regulation of TORC1 by Rag GTPases in nutrient response

Eunjung Kim et al.

NATURE CELL BIOLOGY (2008)

Article Biochemistry & Molecular Biology

SiRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy

Edmond Y. W. Chan et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Biochemistry & Molecular Biology

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

Serhiy Pankiv et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Review Oncology

Control of copper status for cancer therapy

VL Goodman et al.

CURRENT CANCER DRUG TARGETS (2005)

Article Biochemistry & Molecular Biology

Phosphorylation of mammalian target of rapamycin (mTOR) at ser-2448 is mediated by p70S6 kinase

GG Chiang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

TSC2 mediates cellular energy response to control cell growth and survival

K Inoki et al.

Article Cell Biology

Distinct requirements for Ras oncogenesis in human versus mouse cells

NM Hamad et al.

GENES & DEVELOPMENT (2002)

Article Biochemistry & Molecular Biology

Biochemical characterization of the human copper transporter Ctr1

J Lee et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Cell Biology

Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells

N Mizushima et al.

JOURNAL OF CELL BIOLOGY (2001)

Article Multidisciplinary Sciences

A ubiquitin-like system mediates protein lipidation

Y Ichimura et al.

NATURE (2000)