期刊
NATURAL PRODUCT RESEARCH
卷 35, 期 23, 页码 5389-5391出版社
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2020.1768091
关键词
Galuteolin; melanin biosynthesis; skin whitening; tyrosinase; thymus quinquecostatus
资金
- Ministry of Trade, Industry & Energy (MOTIE), Korea Institute for Advancement of Technology (KIAT) through the Encouragement Program for The Industries of Economic Cooperation Region [P0002204]
- Korea Evaluation Institute of Industrial Technology (KEIT) [P0002204] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
This study identified galuteolin in Thymus quinquecostatus flowers as a functional ingredient that effectively inhibits melanin biosynthesis and partially suppresses tyrosinase activity in skin cells, suggesting its potential use as a cosmetic ingredient for skin whitening.
To enhance the skin whitening effect, tyrosinase activity and melanin biosynthesis needs to be suppressed in the skin. To achieve this goal, we examined the extract of Thymus quinquecostatus flowers, and identified a functional ingredient, galuteolin. Galuteolin effectively inhibited melanin biosynthesis in B16/F10 cells, partially suppressing tyrosinase activity. Therefore, this study suggests that galuteolin can be used as a cosmetic ingredient for skin whitening.
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