相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。Applications of fluorine-containing amino acids for drug design
Haibo Mei et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020)
Fluorine-containing drugs approved by the FDA in 2019
Haibo Mei et al.
CHINESE CHEMICAL LETTERS (2020)
The Fluorination of C-H Bonds: Developments and Perspectives
Robert Szpera et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)
The Pharmaceutical Industry in 2018. An Analysis of FDA Drug Approvals from the Perspective of Molecules
Beatriz G. de la Torre et al.
MOLECULES (2019)
Fluorine-Containing Drugs Approved by the FDA in 2018
Haibo Mei et al.
CHEMISTRY-A EUROPEAN JOURNAL (2019)
The Synthesis and Characterization of Highly Fluorinated Aromatic Polyimides
Christopher D. Simone et al.
JOURNAL OF FLUORINE CHEMISTRY (2019)
Convenient Asymmetric Synthesis of Fmoc-(S)-6,6,6-Trifluoro-Norleucine
Haibo Mei et al.
SYMMETRY-BASEL (2019)
New fluorous gelators for perfluorodecalin
Hiroki Miyajima et al.
JOURNAL OF FLUORINE CHEMISTRY (2019)
Asymmetric Synthesis of α-Chloro-α-halo Ketones by Decarboxylative Chlorination of α-Halo-β-ketocarboxylic Acids
Kazumasa Kitahara et al.
SYNTHESIS-STUTTGART (2019)
Large-Scale Asymmetric Synthesis of Fmoc-(S)-2-Amino-6,6,6-Trifluorohexanoic Acid
Zizhen Yin et al.
CHEMISTRYOPEN (2019)
A Comprehensive Review of Non-Covalent Radiofluorination Approaches Using Aluminum [18F]fluoride: Will [18F]AlF Replace 68Ga for Metal Chelate Labeling?
Cyril Fersing et al.
MOLECULES (2019)
Detrifluoroacetylative in Situ Generated Cyclic Fluorinated Enolates for the Preparation of Compounds Featuring a C-F Stereogenic Center
Jiang Liu et al.
ACS OMEGA (2019)
Modern Approaches for Asymmetric Construction of Carbon-Fluorine Quaternary Stereogenic Centers: Synthetic Challenges and Pharmaceutical Needs
Yi Zhu et al.
CHEMICAL REVIEWS (2018)
Synthesis of beta-Fluorovinyliodonium Salts by the Reaction of Alkynes with Hypervalent Iodine/HF Reagents
Tsugio Kitamura et al.
JOURNAL OF ORGANIC CHEMISTRY (2018)
A quantitative reactivity scale for electrophilic fluorinating reagents
Neshat Rozatian et al.
CHEMICAL SCIENCE (2018)
Difluorination of Functionalized Aromatic Olefins Using Hypervalent Iodine/HF Reagents
Tsugio Kitamura et al.
JOURNAL OF ORGANIC CHEMISTRY (2018)
Catalyst-Free Decarboxylative Fluorination of Tertiary -Keto Carboxylic Acids
Misaki Katada et al.
SYNLETT (2018)
Selective Synthesis of Fluorine-Containing Cyclic -Amino Acid Scaffolds
Lorand Kiss et al.
CHEMICAL RECORD (2018)
Recent progress on fluorination in aqueous media
Lian Yang et al.
GREEN CHEMISTRY (2017)
Phosphorus additives for improving high voltage stability and safety of lithium ion batteries
Natascha von Aspern et al.
JOURNAL OF FLUORINE CHEMISTRY (2017)
Hypervalent Iodine/HF Reagents for the Synthesis of 3-Fluoropyrrolidines
Tsugio Kitamura et al.
JOURNAL OF ORGANIC CHEMISTRY (2017)
Recent Advances and Perspectives of Transition Metal-Catalyzed Asymmetric Fluorination Reactions
Chaohuang Chen et al.
CHINESE JOURNAL OF CHEMISTRY (2017)
Development of Shelf-Stable Reagents for Fluoro-Functionalization Reactions
Norio Shibata
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN (2016)
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II-III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
Yu Zhou et al.
CHEMICAL REVIEWS (2016)
Hypervalent iodine(III) fluorinations of alkenes and diazo compounds: new opportunities in fluorination chemistry
Stefanie V. Kohlhepp et al.
CHEMICAL SOCIETY REVIEWS (2016)
Methyl NFSI: atom-economical alternative to NFSI shows higher fluorination reactivity under Lewis acid-catalysis and non-catalysis
Kazunobu Fukushi et al.
GREEN CHEMISTRY (2016)
Fluoride ion batteries: Theoretical performance, safety, toxicity, and a combinatorial screening of new electrodes
F. Gschwind et al.
JOURNAL OF FLUORINE CHEMISTRY (2016)
Diastereoselective Mannich Reactions Using Fluorinated Ketones: Synthesis of Stereogenic Carbon-Fluorine Units
Ya Li et al.
JOURNAL OF ORGANIC CHEMISTRY (2016)
Applications of 19F-NMR in Fragment-Based Drug Discovery
Raymond S. Norton et al.
MOLECULES (2016)
Fluorination methods in drug discovery
Damian E. Yerien et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2016)
Diastereodivergent Access to Syn and Anti 3,4-Substituted β-Fluoropyrrolidines: Enhancing or Reversing Substrate Preference
Kasper Fjelbye et al.
ORGANIC LETTERS (2016)
Advancements in Aminofluorination of Alkenes and Alkynes: Convenient Access to β-Fluoroamines
Pinhong Chen et al.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2015)
Reactions of organozinc reagents with potassium bromodifluoroacetate
Vitalij V. Levin et al.
JOURNAL OF FLUORINE CHEMISTRY (2015)
Hypervalent Iodine-Mediated Fluorination of Styrene Derivatives: Stoichiometric and Catalytic Transformation to 2,2-Difluoroethylarenes
Tsugio Kitamura et al.
JOURNAL OF ORGANIC CHEMISTRY (2015)
Scaling Behavior of Dendritic Nanoparticle Mobility in Semidilute Polymer Solutions
Daan W. de Kort et al.
MACROMOLECULES (2015)
Recent Advances in the Development and Application of Radiolabeled Kinase Inhibitors for PET Imaging
Vadim Bernard-Gauthier et al.
MOLECULES (2015)
Fluorine containing amino acids: synthesis and peptide coupling of amino acids containing the all-cis tetrafluorocyclohexyl motif
Mohammed Salah Ayoup et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2015)
gamma-(S)-Trifluoromethyl proline: evaluation as a structural substitute of proline for solid state F-19-NMR peptide studies
Vladimir Kubyshkin et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2015)
A Highly Regio- and Stereoselective Synthesis of α-Fluorinated Imides via Fluorination of Chiral Enamides
Yan-Shuang Xu et al.
ORGANIC LETTERS (2015)
A Convenient Synthesis of 2-Fluoro- and 2-Chloromalonic Esters Mediated by Hypervalent Iodine
Tsugio Kitamura et al.
SYNTHESIS-STUTTGART (2015)
Using 19F NMR to Probe Biological Interactions of Proteins and Peptides
E. Neil G. Marsh et al.
ACS CHEMICAL BIOLOGY (2014)
Asymmetric synthesis of α-amino acids via homologation of Ni(II) complexes of glycine Schiff bases. Part 3: Michael addition reactions and miscellaneous transformations
Jose Luis Acena et al.
AMINO ACIDS (2014)
Mild Silver-Mediated Geminal Difluorination of Styrenes Using an Air- and Moisture-Stable Fluoroiodane Reagent
Nadia O. Ilchenko et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2014)
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001-2011)
Jiang Wang et al.
CHEMICAL REVIEWS (2014)
Divergent Reaction Mechanisms in the Aminofluorination of Alkenes
Wangqing Kong et al.
CHIMIA (2014)
Successful fluorine-containing herbicide agrochemicals
Tomoya Fujiwara et al.
JOURNAL OF FLUORINE CHEMISTRY (2014)
Preparation of 1,1-difluoroalkanes from aldehydes via 1,1-bistriflates: Advantageous use of HF-Lewis base reagents
William R. Dolbier et al.
JOURNAL OF FLUORINE CHEMISTRY (2014)
Recent advances in the trifluoromethylation methodology and new CF3-containing drugs
Wei Zhu et al.
JOURNAL OF FLUORINE CHEMISTRY (2014)
Hypervalent Iodine-Promoted α-Fluorination of Acetophenone Derivatives with a Triethylamine•HF Complex
Tsugio Kitamura et al.
JOURNAL OF ORGANIC CHEMISTRY (2014)
A Practical Source of Chlorodifluoromethyl Radicals. Convergent Routes to gem-Difluoroalkenes and -dienes and (2,2-Difluoroethyl)-indoles, -azaindoles, and -naphthols
Pierre Salomon et al.
ORGANIC LETTERS (2014)
Boron Trifluoride Etherate Functioning as a Fluorine Source in an Iodosobenzene-Mediated Intramolecular Aminofluorination of Homoallylic Amines
Jian Cui et al.
ORGANIC LETTERS (2014)
Review of recent advances in nucleophilic C-F bond-forming reactions at sp3 centers
Jimmy Wu
TETRAHEDRON LETTERS (2014)
Late-stage [18F]fluorination: new solutions to old problems
Allen F. Brooks et al.
CHEMICAL SCIENCE (2014)
Organocatalytic Asymmetric Michael Addition/Carbon-Carbon Bond Cleavage of Trifluoromethyl α-Fluorinated gem-Diols to Nitroolefins
Ibrayim Saidalimu et al.
ADVANCED SYNTHESIS & CATALYSIS (2013)
Synthesis of Fluorinated Building Blocks by Transition-Metal-Mediated Hydrodefluorination Reactions
Moritz F. Kuehnel et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2013)
Introduction of Fluorine and Fluorine-Containing Functional Groups
Theresa Liang et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2013)
An efficient synthesis of optically active trifluoromethyl aldimines via asymmetric biomimetic transamination
Mao Liu et al.
CHEMICAL COMMUNICATIONS (2013)
19F NMR: a valuable tool for studying biological events
Han Chen et al.
CHEMICAL SOCIETY REVIEWS (2013)
Chiral N-Fluorodibenzenesulfonimide Analogues for Enantioselective Electrophilic Fluorination and Oxidative Fluorination
Chuan-Le Zhu et al.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2013)
Synthesis of fluorine-containing α-amino acids in enantiomerically pure form via homologation of Ni(II) complexes of glycine and alanine Schiff bases
Jose Luis Acena et al.
JOURNAL OF FLUORINE CHEMISTRY (2013)
Recent Trends in Bioorthogonal Click-Radiolabeling Reactions Using Fluorine-18
Marc Pretze et al.
MOLECULES (2013)
Biomimetic Asymmetric 1,3-Dioplar Cycloaddition: Amino Acid Precursors in Biosynthesis Serve as Latent Azomethine Ylides
Chang Guo et al.
ORGANIC LETTERS (2013)
Facile Synthesis of 2-Fluoro-1,3-dicarbonyl Compounds with Aqueous Hydrofluoric Acid Mediated by Iodosylarenes
Tsugio Kitamura et al.
SYNTHESIS-STUTTGART (2013)
Catalytic fluorination of 1,3-dicarbonyl compounds using iodoarene catalysts
Tsugio Kitamura et al.
TETRAHEDRON LETTERS (2013)
Accommodating fluorinated amino acids in a helical peptide environment
Elisabeth K. Nyakatura et al.
RSC ADVANCES (2013)
Recent advances in the synthesis of fluorinated aminophosphonates and aminophosphonic acids
Kostiantyn V. Turcheniuk et al.
RSC ADVANCES (2013)
Design, synthesis, and pharmacological evaluation of benzamide derivatives as glucokinase activators
Weiwei Mao et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2012)
Efficient asymmetric synthesis of trifluoromethylated β-aminophosphonates and their incorporation into dipeptides
Kostiantyn V. Turcheniuk et al.
CHEMICAL COMMUNICATIONS (2012)
Metal free fluoroamination of allylsilanes: A route to 3-fluoropyrrolidines
Lorraine E. Combettes et al.
JOURNAL OF FLUORINE CHEMISTRY (2012)
Multifunctional surface modification of an aramid fabric via direct fluorination
Euigyung Jeong et al.
JOURNAL OF FLUORINE CHEMISTRY (2012)
Discovery of Cyclic Sulfone Hydroxyethylamines as Potent and Selective β-Site APP-Cleaving Enzyme 1 (BACE1) Inhibitors: Structure-Based Design and in Vivo Reduction of Amyloid β-Peptides
Heinrich Rueeger et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Reaction of Iodonium Ylides of 1,3-Dicarbonyl Compounds with HF Reagents
Keisuke Gondo et al.
MOLECULES (2012)
An Efficient Asymmetric Biomimetic Transamination of α-Keto Esters to Chiral α-Amino Esters
Xiao Xiao et al.
ORGANIC LETTERS (2012)
Asymmetric synthesis of phosphonotrifluoroalanine and its derivatives using N-tert-butanesulfinyl imine derived from fluoral
Gerd-Volker Roeschenthaler et al.
TETRAHEDRON LETTERS (2012)
Palladium-Catalyzed Intramolecular Aminofluorination of Styrenes
Xu Tao et al.
CHINESE JOURNAL OF CHEMISTRY (2011)
Biomimetic Transamination - a Metal-Free Alternative to the Reductive Amination. Application for Generalized Preparation of Fluorine-Containing Amines and Amino Acids
Jianlin Han et al.
CURRENT ORGANIC SYNTHESIS (2011)
N-Fluoro-(3,5-di-tert-butyl-4-methoxy)benzenesulfonimide (NFBSI): A sterically demanding electrophilic fluorinating reagent for enantioselective fluorination
Hiroyuki Yasui et al.
JOURNAL OF FLUORINE CHEMISTRY (2011)
Organocatalytic Asymmetric Biomimetic Transamination: From α-Keto Esters to Optically Active α-Amino Acid Derivatives
Xiao Xiao et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2011)
A Practical and Convenient Fluorination of 1,3-Dicarbonyl Compounds Using Aqueous HF in the Presence of Iodosylbenzene
Tsugio Kitamura et al.
ORGANIC LETTERS (2011)
Recent Advances in Catalytic Enantioselective Fluorination Reactions
Sylvain Lectard et al.
ADVANCED SYNTHESIS & CATALYSIS (2010)
Using Fluorine Nuclear Magnetic Resonance To Probe the Interaction of Membrane-Active Peptides with the Lipid Bilayer
Benjamin C. Buer et al.
BIOCHEMISTRY (2010)
One-pot α-nucleophilic fluorination of acetophenones in a deep eutectic solvent
Zizhan Chen et al.
JOURNAL OF FLUORINE CHEMISTRY (2010)
Fluorine in health care Organofluorine containing blockbuster drugs
David O'Hagan
JOURNAL OF FLUORINE CHEMISTRY (2010)
Towards identifying preferred interaction partners of fluorinated amino acids within the hydrophobic environment of a dimeric coiled coil peptide
Toni Vagt et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2010)
Synthesis of aminomethylated 4-fluoropiperidines and 3-fluoropyrrolidines
Guido Verniest et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2010)
The unique role of halogen substituents in the design of modern agrochemicals
Peter Jeschke
PEST MANAGEMENT SCIENCE (2010)
Practical Methods for the Synthesis of Symmetrically α,α-Disubstituted α-Amino Acids
Vadim A. Soloshonok et al.
SYNTHESIS-STUTTGART (2010)
Effects of Fluorination on the Folding Kinetics of a Heterodimeric Coiled Coil
Mario Salwiczek et al.
CHEMBIOCHEM (2009)
General Method for the Synthesis of Phenyliodonium Ylides from Malonate Esters: Easy Access to 1,1-Cyclopropane Diesters
Sebastien R. Goudreau et al.
JOURNAL OF ORGANIC CHEMISTRY (2009)
Synthesis and structure-activity relationships of potent 4-fluoro-2-cyanopyrrolidine dipeptidyl peptidase IV inhibitors
Hiroshi Fukushima et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2008)
Chemistry with [18F]fluoride ion
Lisheng Cai et al.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2008)
A β-fluoroamine inhibitor of purine nucleoside phosphorylase
Jennifer M. Mason et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Electrophilic and nucleophilic side chain fluorination of para-substituted acetophenones
Erik Fuglseth et al.
TETRAHEDRON (2008)
New approaches to enantioselective fluorination: Cinchona alkaloids combinations and chiral ligands/metal complexes
Norio Shibata et al.
JOURNAL OF FLUORINE CHEMISTRY (2007)
Solvent-free fluorination of organic compounds using N-F reagents
Gaj Stavber et al.
TETRAHEDRON LETTERS (2007)
Operationally convenient asymmetric synthesis of (S)- and (R)-3-amino-4,4,4-trifluorobutanoic acid -: Part I:: Enantioselective biomimetic transamination of isopropyl 4,4,4-trifluoro-3-oxo-butanoate
Vadim A. Soloshonok et al.
JOURNAL OF FLUORINE CHEMISTRY (2006)
Operationally convenient asymmetric synthesis of (S)- and (R)-3-amino-4,4,4-trifluorobutanoic acid -: Part II.: Enantioselective biomimetic transamination of 4,4,4-trifluoro-3-oxo-N-[(R)-1-phenylethyl]butanamide
Vadim A. Soloshonok et al.
JOURNAL OF FLUORINE CHEMISTRY (2006)
Fluorine in medicinal chemistry: A review of anti-cancer agents
C Isanbor et al.
JOURNAL OF FLUORINE CHEMISTRY (2006)
Electrophilic fluorination of organosilanes
M Tredwell et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2006)
Construction of asymmetric fluorinated carbon centers
GKS Prakash et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2006)
A novel synthesis of fluorine-containing quaternary amino acid derivatives via palladium-catalyzed allylation reaction
T Konno et al.
JOURNAL OF FLUORINE CHEMISTRY (2005)
Discovery of potent and selective phenylalanine based dipeptidyl peptidase IV inhibitors
JY Xu et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2005)
Cocatalysis in phase-transfer catalyzed fluorination of alkyl halides and sulfonates
M Makosza et al.
JOURNAL OF FLUORINE CHEMISTRY (2005)
Fluoropyrrolidine amides as dipeptidyl peptidase IV inhibitors
CG Caldwell et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2004)
Evaluation of the molecular interactions of fluorinated amino acids with native polypepticles
C Jäckel et al.
CHEMBIOCHEM (2004)
Titanium-catalyzed stereoselective geminal heterodihalogenation of β-ketoesters
R Frantz et al.
ORGANIC LETTERS (2003)
Reactions of trifluoroamine oxide:: a new method for selective fluorination of 1,3-diketones and β-ketoesters
OD Gupta et al.
TETRAHEDRON LETTERS (2003)
Simple and efficient syntheses of Boc- and Fmoc-protected 4(R)- and 4(S)-fluoroproline solely from 4(R)-hydroxyproline
M Doi et al.
TETRAHEDRON (2002)
Synthesis of optically pure N-Boc-protected (2R,3R)- and (2R,3S)-3-fluoroprolines
L Demange et al.
TETRAHEDRON LETTERS (2001)
Design, synthesis, and evaluation of a novel class of enantioselective electrophilic fluorinating agents:: N-fluoro ammonium salts of cinchona alkaloids (F-CA-BF4)
D Cahard et al.
ORGANIC LETTERS (2000)
A fundamentally new approach to enantioselective fluorination based on cinchona alkaloid derivatives/selectfluor combination
N Shibata et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2000)
Rearrangement of phenylethenes on reaction with iodine-xenon difluoride
TB Patrick et al.
ORGANIC LETTERS (2000)
Fluorination of alkenes by iodoarene difluorides
M Sawaguchi et al.
JOURNAL OF FLUORINE CHEMISTRY (2000)
分享论文
