期刊
MOLECULAR & CELLULAR PROTEOMICS
卷 19, 期 8, 页码 1248-1262出版社
AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
DOI: 10.1074/mcp.RA119.001826
关键词
-
资金
- BBSRC David Phillips Fellowship [BB_BB/H022457/1]
- Marie Curie European Reintegration Grant [PERG06-GA-2009-256354]
- Vetenskapsradet
- VINNOVA
- Knut and Alice Wallenberg Foundation
- CEPLAS (Deutsche Forschungsgemeinschaft) [EXC 1028]
- German Research Council (DFG)
- Paul G. Allen Family Foundation
- National Science Foundation [IOS-0919021]
- National Institutes of Health [T32HD007183]
- BBSRC Professorial Research Fellowship
- Biotechnology and Biological Sciences Research Council (BBSRC)
- Engineering and Physical Sciences Research Council (EPSRC)
- Interuniversity Attraction Poles Programme from the Belgian Federal Science Policy Office [IAP VI/33, IUAP P7/29]
- Research Foundation Flanders (FWO)
- Biotechnology and Biological Science Research Council
- Agency for Innovation by Science and Technology (IWT)
- Next-Generation BioGreen 21 Program, Republic of Korea [PJ01342301]
- Swedish Research Council (VR)
- Swedish Governmental Agency for Innovation Systems (VINNOVA)
- Chinese Scholarship Council
- BBSRC [BB/H022457/1] Funding Source: UKRI
Peptides derived from non-functional precursors play important roles in various developmental processes, but also in (a)biotic stress signaling. Our (phospho)proteome-wide analyses of C-TERMINALLY ENCODED PEPTIDE 5 (CEP5)-mediated changes revealed an impact on abiotic stress-related processes. Drought has a dramatic impact on plant growth, development and reproduction, and the plant hormone auxin plays a role in drought responses. Our genetic, physiological, biochemical, and pharmacological results demonstrated that CEP5-mediated signaling is relevant for osmotic and drought stress tolerance in Arabidopsis, and that CEP5 specifically counteracts auxin effects. Specifically, we found that CEP5 signaling stabi-lizes AUX/IAA transcriptional repressors, suggesting the existence of a novel peptide-dependent control mechanism that tunes auxin signaling. These observations align with the recently described role of AUX/IAAs in stress tolerance and provide a novel role for CEP5 in osmotic and drought stress tolerance.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据