相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Hepatic ferroptosis plays an important role as the trigger for initiating inflammation in nonalcoholic steatohepatitis
Shinya Tsurusaki et al.
CELL DEATH & DISEASE (2019)
The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis
Kirill Bersuker et al.
NATURE (2019)
Dynamics and functions of lipid droplets
James A. Olzmann et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)
The diagnosis and management of nonalcoholic fatty liver disease: Practice guidance from the American Association for the Study of Liver Diseases
Naga Chalasani et al.
HEPATOLOGY (2018)
Modeling the epidemic of nonalcoholic fatty liver disease demonstrates an exponential increase in burden of disease
Chris Estes et al.
HEPATOLOGY (2018)
Gasdermin D plays a key role as a pyroptosis executor of non-alcoholic steatohepatitis in humans and mice
Bing Xu et al.
JOURNAL OF HEPATOLOGY (2018)
Super-resolution microscopy localizes perilipin 5 at lipid droplet-mitochondria interaction sites and at lipid droplets juxtaposing to perilipin 2
Anne Gemmink et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2018)
Current and upcoming pharmacotherapy for non-alcoholic fatty liver disease
Yaron Rotman et al.
GUT (2017)
Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis
Valerian E. Kagan et al.
NATURE CHEMICAL BIOLOGY (2017)
Characterization of Ferroptosis in Murine Models of Hemochromatosis
Hao Wang et al.
HEPATOLOGY (2017)
Lipid Zonation and Phospholipid Remodeling in Nonalcoholic Fatty Liver Disease
Zoe Hall et al.
HEPATOLOGY (2017)
Liver inflammation and fibrosis
Yukinori Koyama et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
Fibrosis stage but not NASH predicts mortality and time to development of severe liver disease in biopsy-proven NAFLD
Hannes Hagstrom et al.
JOURNAL OF HEPATOLOGY (2017)
Lipid droplets and liver disease: from basic biology to clinical implications
Nina L. Gluchowski et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2017)
Ablation of ferroptosis regulator glutathione peroxidase 4 in forebrain neurons promotes cognitive impairment and neurodegeneration
William Sealy Hambright et al.
REDOX BIOLOGY (2017)
Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease
Brent R. Stockwell et al.
CELL (2017)
Nonalcoholic Fatty Liver Disease: Pathogenesis and Disease Spectrum
Timothy Hardy et al.
ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 11 (2016)
Pathogenesis of Nonalcoholic Steatohepatitis
Mariana Verdelho Machado et al.
GASTROENTEROLOGY (2016)
MCD diet-induced steatohepatitis is associated with alterations in asymmetric dimethylarginine (ADMA) and its transporters
Laura G. Di Pasqua et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2016)
Non-alcoholic steatohepatitis: emerging molecular targets and therapeutic strategies
Giovanni Musso et al.
NATURE REVIEWS DRUG DISCOVERY (2016)
Antioxidant Role for Lipid Droplets in a Stem Cell Niche of Drosophila
Andrew P. Bailey et al.
CELL (2015)
Glial Lipid Droplets and ROS Induced by Mitochondrial Defects Promote Neurodegeneration
Lucy Liu et al.
CELL (2015)
Necroptosis is a key pathogenic event in human and experimental murine models of non-alcoholic steatohepatitis
Marta B. Afonso et al.
CLINICAL SCIENCE (2015)
Enhanced expression of BMP6 inhibits hepatic fibrosis in non-alcoholic fatty liver disease
Stephanie Arndt et al.
GUT (2015)
Regulation of Ferroptotic Cancer Cell Death by GPX4
Wan Seok Yang et al.
CELL (2014)
Cell Death and Cell Death Responses in Liver Disease: Mechanisms and Clinical Relevance
Tom Luedde et al.
GASTROENTEROLOGY (2014)
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
Jose Pedro Friedmann Angeli et al.
NATURE CELL BIOLOGY (2014)
Iron homeostasis in the Metabolic Syndrome
Christian Datz et al.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION (2013)
Development of small-molecule inhibitors targeting adipose triglyceride lipase
Nicole Mayer et al.
NATURE CHEMICAL BIOLOGY (2013)
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
Scott J. Dixon et al.
CELL (2012)
Group IVA phospholipase A2 participates in the progression of hepatic fibrosis
Keiichi Ishihara et al.
FASEB JOURNAL (2012)
Hepcidin and the Iron-Infection Axis
Hal Drakesmith et al.
SCIENCE (2012)
RIP3 mediates the embryonic lethality of caspase-8-deficient mice
William J. Kaiser et al.
NATURE (2011)
Stress Signaling in the Methionine-Choline-Deficient Model of Murine Fatty Liver Disease
Russell K. Soon et al.
GASTROENTEROLOGY (2010)
Disruption of the 12/15-Lipoxygenase Gene (Alox15) Protects Hyperlipidemic Mice from Nonalcoholic Fatty Liver Disease
Marcos Martinez-Clemente et al.
HEPATOLOGY (2010)
Impact of pan-caspase inhibition in animal models of established steatosis and non-alcoholic steatohepatitis
Quentin M. Anstee et al.
JOURNAL OF HEPATOLOGY (2010)
The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome
Jung Sub Lim et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2010)
Autophagy regulates lipid metabolism
Rajat Singh et al.
NATURE (2009)
Hepatic steatosis in leptin-deficient mice is promoted by the PPARγ target gene Fsp27
Kimihiko Matsusue et al.
CELL METABOLISM (2008)
Role of HIF-1 and NF-κB transcription factors in the modulation of transferrin receptor by inflammatory and anti-inflammatory signals
Lorenza Tacchini et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
NADPH oxidase is not an essential mediator of oxidative stress or liver injury in murine MCD diet-induced steatohepatitis
Aileen dela Pena et al.
JOURNAL OF HEPATOLOGY (2007)
Effects of iron overload in a rat nutritional model of non-alcoholic fatty liver disease
Richard Kirsch et al.
LIVER INTERNATIONAL (2006)
Synthesis and structure-activity relationship for a novel class of potent and selective carbamoyl-triazole based inhibitors of hormone sensitive lipase
S Ebdrup et al.
JOURNAL OF MEDICINAL CHEMISTRY (2004)
The methionine-choline deficient dietary model of steatohepatitis does not exhibit insulin resistance
ME Rinella et al.
JOURNAL OF HEPATOLOGY (2004)
Effect of iron overload and dietary fat on indices of oxidative stress and hepatic fibrogenesis in rats
KE Brown et al.
LIVER INTERNATIONAL (2003)
Hepatocyte apoptosis and Fas expression are prominent features of human nonalcoholic steatohepatitis
AE Feldstein et al.
GASTROENTEROLOGY (2003)
Biological significance of phospholipid hydroperoxide glutathione peroxidase (PHGPx, GPx4) in mammalian cells
H Imai et al.
FREE RADICAL BIOLOGY AND MEDICINE (2003)
Nonalcoholic fatty liver disease: Predictors of nonalcoholic steatohepatitis and liver fibrosis in the severely obese
JB Dixon et al.
GASTROENTEROLOGY (2001)
CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis
IA Leclercq et al.
JOURNAL OF CLINICAL INVESTIGATION (2000)